Saias masculinas: um projeto interdisciplinar por meio da arte, design, artesanato e moda

This article aims to report and discuss an interdisciplinary activity carriedout during the first academic period in an undergraduate course in Fashion Design between the disciplines of Fashion History and Clothing, Fundamentals and History of Design, Modeling and Fashion Design. This practice mobilized knowledge of art,crafts and fashion in the development of men's skirts presented in the form of a fashion show. As a result, it is discussed how the integration of knowledge is relevant for designers in training so that they understand design in a critical, reflective andintegrative way, translating artistic, craft and technological knowledge into theproducts designed.Este artículo tiene como objetivo informar y discutir una actividad interdisciplinar desarrollada durante el primer período académico en un curso de pregrado en Diseño de Moda entre las disciplinas de Historia de la Moda y Confección, Fundamentos e Historia del Diseño, Modelado y Diseño de Moda. Esta práctica movilizó el conocimiento del arte, la artesanía y la moda en la elaboración de faldasmasculinas presentadas en forma de desfile de moda. Como resultado, se discute cómo la integración de conocimientos es relevante para los diseñadores en formación para que comprendan el diseño de forma crítica, reflexiva e integradora, traduciendo los conocimientos artísticos, artesanales y tecnológicos en los productosdiseñados.Esse artigo têm como objetivo relatar e discutir uma atividade interdisciplinar realizada ao longo do primeiro período letivo num curso de graduação em Design de Moda entre as disciplinas de História da Moda e da Indumentária, Fundamentos e História do Design, Modelagem e Desenho de Moda. Esta prática mobilizou conhecimentos da arte, do artesanato e da moda no desenvolvimento de saias masculinas apresentadas na forma de um desfile. Como resultado, discute-se como a integração de conhecimentos é relevante para os designers em formação para que compreendam o design de forma crítica, reflexiva e integrativa traduzindo nos produtos concebidos, os conhecimentos artísticos, artesanais e tecnológicos

Manual del SoftwareIfs Construction kit para generar imágenes que representan fractales mediante sistemas de funciones iteradas

Los últimos avances en matemáticas en el campo de geometría fractal han permitido el surgimiento de una gran variedad de aplicaciones informáticas útiles para la representación de conjuntos fractales. Este trabajo pretende presentar a IFSConstruction Kit como una opción para construir fractales con base en los sistemas de funciones iteradas

Single nucleotide polymorphisms of the genes IL-2, IL-2RB, and JAK3 in patients with cutaneous leishmaniasis caused by Leishmania (V.) guyanensis in Manaus, Amazonas, Brazil

Leishmaniasis is a disease caused by intracellular protozoan parasites of the genus Leishmania. In endemic areas, only a portion of exposed subjects develops cutaneous leishmaniasis (CL), suggesting that the genetic inheritance of the host plays a vital role in both resistance and susceptibility to the disease. Interleukin-2 (IL-2) is a cytokine that plays a central role in the regulation of the immune response in infection through the axis IL-2/IL-2R (receptor) complex, triggering a series of intracellular events, among which the signaling of Janus kinase/signal transducers and activators of transcription (JAK-STAT). The present study aimed at verifying the possible relationship between single nucleotide polymorphism (s) (SNP s) in the genes IL-2, IL-2RB, and JAK3 in subjects with CL caused by Leishmania guyanensis in the city of Manaus, state of Amazonas, Brazil. 820 patients with CL and 850 healthy subjects (control group) coming from the same endemic areas as the patients were examined. The SNPs -2425G/A (rs4833248) and -330 T/G (rs2069762), located in the IL-2 gene promoter region, seem to influence the expression of the gene and the SNP +10558G/A (rs1003694) and +13295T/C (rs3212760) located in the 3rd intron of the IL-2RB gene and the 13th intron of the JAK3 gene, respectively, were studied by PCR-RFLP. Genotypes and alleles frequencies were obtained by direct counting. For the comparison between the two groups, the χ2 test with OR (odds ratio) and the 95% confidence interval (CI) were used. Similar genotypes and alleles frequencies for the different SNPs were observed in both patients with CL and healthy controls. Comparison of genotypic and allelic frequency between patients with CL and healthy subjects did not show any difference. These polymorphisms do not predict susceptibility to, or protection against the development of CL caused by L. guyanensis in the Amazonas. © 2019 de Araújo Santos et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Vulnerability of Brazilian municipalities to hantavirus infections based on multi‑criteria decision analysis

Background: Hantavirus infection is an emerging zoonosis transmitted by wild rodents. In Brazil, high case-fatality rates among humans infected with hantavirus are of serious concern to public health authorities. Appropriate preventive measures partly depend on reliable knowledge about the geographical distribution of this disease. Methods: Incidence of hantavirus infections in Brazil (1993–2013) was analyzed. Epidemiological, socioeconomic, and demographic indicators were also used to classify cities’ vulnerability to disease by means of multi-criteria decision analysis (MCDA). Results: From 1993 to 2013, 1752 cases of hantavirus were registered in 16 Brazilian states. The highest incidence of hantavirus was observed in the states of Mato Grosso (0.57/100,000) and Santa Catarina (0.13/100,000). Based on MCDA analysis, municipalities in the southern, southeastern, and midwestern regions of Brazil can be classified as highly vulnerable. Most municipalities in northern and northeastern Brazil were classified as having low vulnerability to hantavirus cardiopulmonary syndrome. Conclusions: Although most human infections by hantavirus registered in Brazil occurred in the southern region of the country, a greater vulnerability to hantavirus was found in the Brazilian Midwest. This result reflects the need to strengthen surveillance where the disease has thus far gone unreported