23,643 research outputs found

    Study reveals effect of aluminum on saturation moment of Fe-Ni alloys

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    Study of saturation magnetization, important in the investigation of the electronic structure of alloys, reveals the effect of aluminum on the saturation moments of iron-nickel alloys. The saturation magnetizations were extrapolated to the absolute zero of temperature for calculating average atomic moments

    Innovation and Foreign Investment Behavior of the U.S. Pharmaceutical Industry

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    This paper deals with the links between the development of new drugs, and particularly of innovative new drugs, and the international activities of U.S. drug companies. While U.S. drug companies have developed new production processes - the most notable being the fermentation process for making penicillin - we concentrate in this paper on new products. Since production costs comprise less than 40 percent of the selling price of drugs and since the person choosing the drug rarely pays for it, growth in company sales and profits comes more from introducing new products than from cutting costs and prices of old products. The main novelty of our study is our examination of "innovative" as contrasted with "imitative" new drugs. Previous studies have generally focused on the total number of new drugs produced each year, but since our interest is in the causes and consequences of innovation, we have concentrated on the products we have rated as innovative. Section I explains our criteria for this distinction and presents our enumeration of the innovative new drugs for each of the 22 companies in our sample. In Section II we discuss trends in the rate of drug innovation and the factors influencing those trends. Section III describes our sample of drug companies and characterizes them with respect to their size, research investment, and innovativeness. Section IV examines the relation of innovativeness to the foreign activities of individual firms. In Section V we analyze, for a sample of 7 new drugs introduced by two companies, the rate at which use of the drugs was diffused among various countries arid the impact of the presence of manufacturing plants on the rate of diffusion.

    Financing Africa: Through the crisis and beyond.

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    [Dataset available: http://hdl.handle.net/10411/17679]

    The New Zealand Strong Motion Earthquake Recorder Network

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    The network of strong-motion earthquake recorders, maintained throughout New Zealand by the Engineering Seismology Section of the Department of Scientific and Industrial Research, is described. The instruments are either deployed as ground instruments to measure potential earthquake attack on structures, or in structures, e.g. buildings, dams and industrial installations, to record structural response. Details are given of installation of instruments , maintenance, laboratory work, record retrieval and digitisation, costs and staffing for the network. Future developments mooted include an improved digitising system, the introduction of an improved version of the existing mechanical-optical instrument in 1979, and, in the long term, the introduction of an entirely new digital recorder, having an electrical output from its accelerometers, which will make possible the transmission of data by telephone or radio link

    Measuring non-extensitivity parameters in a turbulent Couette-Taylor flow

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    We investigate probability density functions of velocity differences at different distances r measured in a Couette-Taylor flow for a range of Reynolds numbers Re. There is good agreement with the predictions of a theoretical model based on non-extensive statistical mechanics (where the entropies are non-additive for independent subsystems). We extract the scale-dependent non-extensitivity parameter q(r, Re) from the laboratory data.Comment: 8 pages, 5 figure

    Identification of SH Δv=1\Delta v=1 ro-vibrational lines in R And

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    We report the identification of SH Δv=1\Delta v=1 ro-vibrational lines in the published high-resolution infrared spectrum of the S-type star, R And. This is the first astronomical detection of this molecule. The lines show inverse P-Cygni profiles, indicating infall motion of the molecular layer due to stellar pulsation. A simple spherical shell model with a constant infall velocity is adopted to determine the condition of the layer. It is found that a single excitation temperature of 2200 K reproduces the observed line intensities satisfactory. SH is located in a layer from 1.0 to ~1.1 stellar radii, which is moving inward with a velocity of 9 km s-1. These results are consistent with the previous measurements of CO Δv=3\Delta v=3 transitions. The estimated molecular abundance SH/H is 1x10^-7, consistent with a thermal equilibrium calculation.Comment: 10 pages, 2 figures. Accepted for publication in ApJ Letter

    11. Premunition in Plasmodium falciparum infection: insights from the epidemiology of multiple infections

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    Epidemiological studies of multiple clone infections by Plasmodium falciparum in highly endemic areas have demonstrated age dependence in both the multiplicity of infection and the relationships between this multiplicity and the risk of acute illness. We hypothesize that, in infants, host defence against blood-stage infections with P falciparum relies mainly on fever and cytokine activities, and the infections are of short duration. In older children, a high multiplicity of infection is characteristic of low-level chronic parasitaemia. This appears to confer cross-protection against newly inoculated parasites, via partially genotype-specific responses which are short-term, lasting little longer than the infections themselves. This has important implications for our understanding of immunity against P. falciparum, its ecological niche, and the epidemiological impact of interventions against i

    1. General introduction

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