The cuticle

The nematode cuticle is an extremely flexible and resilient exoskeleton that permits locomotion via attachment to muscle, confers environmental protection and allows growth by molting. It is synthesised five times, once in the embryo and subsequently at the end of each larval stage prior to molting. It is a highly structured extra-cellular matrix (ECM), composed predominantly of cross-linked collagens, additional insoluble proteins termed cuticlins, associated glycoproteins and lipids. The cuticle collagens are encoded by a large gene family that are subject to strict patterns of temporal regulation. Cuticle collagen biosynthesis involves numerous co- and post-translational modification, processing, secretion and cross-linking steps that in turn are catalysed by specific enzymes and chaperones. Mutations in individual collagen genes and their biosynthetic pathway components can result in a range of defects from abnormal morphology (dumpy and blister) to embryonic and larval death, confirming an essential role for this structure and highlighting its potential as an ECM experimental model system

Effect of stellar wind induced magnetic fields on planetary obstacles of non-magnetized hot Jupiters

We investigate the interaction between the magnetized stellar wind plasma and the partially ionized hydrodynamic hydrogen outflow from the escaping upper atmosphere of non- or weakly magnetized hot Jupiters. We use the well-studied hot Jupiter HD 209458b as an example for similar exoplanets, assuming a negligible intrinsic magnetic moment. For this planet, the stellar wind plasma interaction forms an obstacle in the planet's upper atmosphere, in which the position of the magnetopause is determined by the condition of pressure balance between the stellar wind and the expanded atmosphere, heated by the stellar extreme ultraviolet (EUV) radiation. We show that the neutral atmospheric atoms penetrate into the region dominated by the stellar wind, where they are ionized by photo-ionization and charge exchange, and then mixed with the stellar wind flow. Using a 3D magnetohydrodynamic (MHD) model, we show that an induced magnetic field forms in front of the planetary obstacle, which appears to be much stronger compared to those produced by the solar wind interaction with Venus and Mars. Depending on the stellar wind parameters, because of the induced magnetic field, the planetary obstacle can move up to ~0.5-1 planetary radii closer to the planet. Finally, we discuss how estimations of the intrinsic magnetic moment of hot Jupiters can be inferred by coupling hydrodynamic upper planetary atmosphere and MHD stellar wind interaction models together with UV observations. In particular, we find that HD 209458b should likely have an intrinsic magnetic moment of 10-20% that of Jupiter.Comment: 8 pages, 6 figures, 2 tables, accepted to MNRA

Mid-J CO Shock Tracing Observations of Infrared Dark Clouds I

Infrared dark clouds (IRDCs) are dense, molecular structures in the interstellar medium that can harbour sites of high-mass star formation. IRDCs contain supersonic turbulence, which is expected to generate shocks that locally heat pockets of gas within the clouds. We present observations of the CO J = 8-7, 9-8, and 10-9 transitions, taken with the Herschel Space Observatory, towards four dense, starless clumps within IRDCs (C1 in G028.37+00.07, F1 and F2 in G034.43+0007, and G2 in G034.77-0.55). We detect the CO J = 8-7 and 9-8 transitions towards three of the clumps (C1, F1, and F2) at intensity levels greater than expected from photodissociation region (PDR) models. The average ratio of the 8-7 to 9-8 lines is also found to be between 1.6 and 2.6 in the three clumps with detections, significantly smaller than expected from PDR models. These low line ratios and large line intensities strongly suggest that the C1, F1, and F2 clumps contain a hot gas component not accounted for by standard PDR models. Such a hot gas component could be generated by turbulence dissipating in low velocity shocks.Comment: 14 pages, 8 figures, 5 tables, accepted by A&A, minor updates to match the final published versio

Emergence of fractal behavior in condensation-driven aggregation

We investigate a model in which an ensemble of chemically identical Brownian particles are continuously growing by condensation and at the same time undergo irreversible aggregation whenever two particles come into contact upon collision. We solved the model exactly by using scaling theory for the case whereby a particle, say of size $x$, grows by an amount $\alpha x$ over the time it takes to collide with another particle of any size. It is shown that the particle size spectra of such system exhibit transition to dynamic scaling $c(x,t)\sim t^{-\beta}\phi(x/t^z)$ accompanied by the emergence of fractal of dimension $d_f={{1}\over{1+2\alpha}}$. One of the remarkable feature of this model is that it is governed by a non-trivial conservation law, namely, the $d_f^{th}$ moment of $c(x,t)$ is time invariant regardless of the choice of the initial conditions. The reason why it remains conserved is explained by using a simple dimensional analysis. We show that the scaling exponents $\beta$ and $z$ are locked with the fractal dimension $d_f$ via a generalized scaling relation $\beta=(1+d_f)z$.Comment: 8 pages, 6 figures, to appear in Phys. Rev.

Eigenvalue distributions for some correlated complex sample covariance matrices

The distributions of the smallest and largest eigenvalues for the matrix product $Z^\dagger Z$, where $Z$ is an $n \times m$ complex Gaussian matrix with correlations both along rows and down columns, are expressed as $m \times m$ determinants. In the case of correlation along rows, these expressions are computationally more efficient than those involving sums over partitions and Schur polynomials reported recently for the same distributions.Comment: 11 page

Conceptual design of a nonscaling fixed field alternating gradient accelerator for protons and carbon ions for charged particle therapy

Published by the American Physical Society under the terms of the Creative Commons Attribution 3.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI.The conceptual design for a nonscaling fixed field alternating gradient accelerator suitable for charged particle therapy (the use of protons and other light ions to treat some forms of cancer) is described.EPSR