501 research outputs found

    Solitary flexural–gravity waves in three dimensions

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    The focus of this work is on three-dimensional nonlinear flexural–gravity waves, propagating at the interface between a fluid and an ice sheet. The ice sheet is modelled using the special Cosserat theory of hyperelastic shells satisfying Kirchhoff's hypothesis, presented in (Plotnikov & Toland. 2011 Phil. Trans. R. Soc. A 369, 2942–2956 (doi:10.1098/rsta.2011.0104)). The fluid is assumed inviscid and incompressible, and the flow irrotational. A numerical method based on boundary integral equation techniques is used to compute solitary waves and forced waves to Euler's equations. This article is part of the theme issue ‘Modelling of sea-ice phenomena’

    Finite depth effects on solitary waves in a floating ice sheet

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    A theoretical and numerical study of two-dimensional nonlinear flexural-gravity waves propagating at the surface of an ideal fluid of finite depth, covered by a thin ice sheet, is presented. The ice-sheet model is based on the special Cosserat theory of hyperelastic shells satisfying Kirchhoff׳s hypothesis, which yields a conservative and nonlinear expression for the bending force. From a Hamiltonian reformulation of the governing equations, two weakly nonlinear wave models are derived: a 5th-order Korteweg–de Vries equation in the long-wave regime and a cubic nonlinear Schrödinger equation in the modulational regime. Solitary wave solutions of these models and their stability are analysed. In particular, there is a critical depth below which the nonlinear Schrödinger equation is of focusing type and thus admits stable soliton solutions. These weakly nonlinear results are validated by comparison with direct numerical simulations of the full governing equations. It is observed numerically that small- to large-amplitude solitary waves of depression are stable. Overturning waves of depression are also found for low wave speeds and sufficiently large depth. However, solitary waves of elevation seem to be unstable in all cases

    Superform formulation for vector-tensor multiplets in conformal supergravity

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    The recent papers arXiv:1110.0971 and arXiv:1201.5431 have provided a superfield description for vector-tensor multiplets and their Chern-Simons couplings in 4D N = 2 conformal supergravity. Here we develop a superform formulation for these theories. Furthermore an alternative means of gauging the central charge is given, making use of a deformed vector multiplet, which may be thought of as a variant vector-tensor multiplet. Its Chern-Simons couplings to additional vector multiplets are also constructed. This multiplet together with its Chern-Simons couplings are new results not considered by de Wit et al. in hep-th/9710212.Comment: 28 pages. V2: Typos corrected and references updated; V3: References updated and typo correcte

    Rehabilitacja kardiologiczna u pacjentów po zawale serca

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    Cardiac rehabilitation is a holistic action aimed at preventing heart diseases, treatment and improving the quality of life and functionality of patients, limiting the progression of the diseases and reducing mortality resulting from cardiovascular diseases. Physiotherapy plays an important role in cardiac rehabilitation, but also proper pharmacological therapy, psychotherapy, dietary therapy, education on cardiovascular system and modification of the current lifestyle by the patient.Rehabilitacja kardiologiczna jest całościowym działaniem mającym na celu prewencję chorób serca, leczenie oraz poprawę jakości życia i funkcjonowania pacjentów, ograniczenie postępów choroby oraz zmniejszenie śmiertelności wynikającej z chorób układu krążenia. W rehabilitacji kardiologicznej ważną rolę odgrywają ćwiczenia fizyczne, ale również właściwa terapia farmakologiczna, psychoterapia, leczenie dietetyczne, edukacja na temat układu krążenia oraz modyfikacja przez pacjenta dotychczasowego stylu życia

    Wess-Zumino sigma models with non-Kahlerian geometry

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    Supersymmetry of the Wess-Zumino (N=1, D=4) multiplet allows field equations that determine a larger class of geometries than the familiar Kahler manifolds, in which covariantly holomorphic vectors rather than a scalar superpotential determine the forces. Indeed, relaxing the requirement that the field equations be derivable from an action leads to complex flat geometry. The Batalin-Vilkovisky formalism is used to show that if one requires that the field equations be derivable from an action, we once again recover the restriction to Kahler geometry, with forces derived from a scalar superpotential.Comment: 13 pages, Late

    A PDZ-Binding Motif is Essential but Not Sufficient to Localize the C Terminus of CFTR to the Apical Membrane

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    Localization of ion channels and transporters to the correct membrane of polarized epithelia is important for vectorial ion movement. Prior studies have shown that the cytoplasmic carboxyl terminus of the cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the apical localization of this protein. Here we show that the C-terminal tail alone, or when fused to the green fluorescent protein (GFP), can localize to the apical plasma membrane, despite the absence of transmembrane domains. Co-expression of the C terminus with full-length CFTR results in redistribution of CFTR from apical to basolateral membranes, indicating that both proteins interact with the same target at the apical membrane. Amino acid substitution and deletion analysis confirms the importance of a PDZ-binding motif D-T-R-L\u3e for apical localization. However, two other C-terminal regions, encompassing amino acids 1370-1394 and 1404-1425 of human CFTR, are also required for localizing to the apical plasma membrane. Based on these results, we propose a model of polarized distribution of CFTR, which includes a mechanism of selective retention of this protein in the apical plasma membrane and stresses the requirement for other C-terminal sequences in addition to a PDZ-binding motif
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