6,148 research outputs found

    Application of confidential intervals for verification of reservoir model at interpretation of well test data

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    The information on arguments of an oil reservoir to a well test from the point of view of the Bayesian inference are express through even allocation of odds in room of arguments. In article application of confidential spacing for a quantitative appraisal of the information receive from the analysis of results of well test which one are us for upgrading of allocations of odds are offered. Use of confidential spacing for an appraisal of a correctness of a choice of a laboratory formation are show

    Comprehensive analysis of draft genomes of two closely related pseudomonas syringae phylogroup 2b strains infecting mono- and dicotyledon host plants

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    Comparison of the prophage region in Pseudomonas syringae strain SM (A) with the corresponding regions in strains 1845 (B) and 2507 (C) using MAUVE software (Darling et al. 2010). (PNG 2118 kb

    Predicting the solvation of organic compounds in aqueous environments: from alkanes and alcohols to pharmaceuticals

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    The development of accurate models to predict the solvation, solubility, and partitioning of nonpolar and amphiphilic compounds in aqueous environments remains an important challenge. We develop state-of-the-art group-interaction models that deliver an accurate description of the thermodynamic properties of alkanes and alcohols in aqueous solution. The group-contribution formulation of the statistical associating fluid theory based on potentials with a variable Mie form (SAFT-γ Mie) is shown to provide accurate predictions of the phase equilibria, including liquid–liquid equilibria, solubility, free energies of solvation, and other infinite-dilution properties. The transferability of the model is further exemplified with predictions of octanol–water partitioning and solubility for a range of organic and pharmaceutically relevant compounds. Our SAFT-γ Mie platform is reliable for the prediction of challenging properties such as mutual solubilities of water and organic compounds which can span over 10 orders of magnitude, while remaining generic in its applicability to a wide range of compounds and thermodynamic conditions. Our work sheds light on contradictory findings related to alkane–water solubility data and the suitability of models that do not account explicitly for polarity

    The intellectual information system for management of geological and technical arrangements during oil field exploitation

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    The intellectual information system for management of geological and technical arrangements during oil fields exploitation is developed. Service-oriented architecture of its software is a distinctive feature of the system. The results of the cluster analysis of real field data received by means of this system are shown

    Low-energy quenching of positronium by helium

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    Very low-energy scattering of orthopositronium by helium has been investigated for simultaneous study of elastic cross section and pick-off quenching rate using a model exchange potential. The present calculational scheme, while agrees with the measured cross section of Skalsey et al, reproduces successfully the parameter ^ 1Z_{\makebox{eff}}, the effective number of electrons per atom in a singlet state relative to the positron. Together with the fact that this model potential also leads to an agreement with measured medium energy cross sections of this system, this study seems to resolve the long-standing discrepancy at low energies among different theoretical calculations and experimental measurements.Comment: 4 latex pages, 3 postscript figure

    MHD Modeling of the Molecular Filament Evolution

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    В работе выполняется численное магнитогазодинамическое (МГД) моделирование гравитационного коллапса цилиндрического молекулярного облака с помощью кода FLASH. В расчетах с магнитным полем и без магнитного поля на концах облака формируются ядра с концентрациями n ≈ 1.3 · 106 см−3 и 3.7 · 106 см−3 соответственно. Ядра передвигаются к центру со скоростью v ≈ 5.5 км·с−1, их размеры вдоль радиуса и оси волокна составляют соответственно 0.16 и 0.05 пк для случая с магнитным полем, 0.06 и 0.05 пк для случая без магнитного поля. Скорости ядер в обоих случаях совпадают, так как магнитное поле является продольным и не влияет на сжатие вдоль цилиндра. Получаемые скорости ядер согласуются с наблюдаемыми значениями в волокнах.We perform numerical magnetohydrodynamic (MHD) simulations of gravitational collapse of cylindrical molecular cloud with the help of the code FLASH. In simulations with magnetic field and without it, cores are formed at the edges of cloud with densities n ≈ 1.3·106 cm−3 and 3.7·106 cm−3 respectively. Cores are moving toward cloud center with velocity v ≈ 5.5 km·s−1, in simulations with magnetic filed cores sizes along radius and filament axis are 0.16 and 0.05 pc respectively, while in simulations without magnetic field core sizes are 0.06, 0.05 pc. Cores velocities are coincide in both cases, because of magnetic field that is parallel and has no effect on collapse alongside of cylinder. Core velocities are correlated with observational data in filaments.Работа С. А. Хайбрахманова выполнена при поддержке Министерства науки и высшего образования Российской Федерации, тема FEUZ-2023-0019. Авторы благодарят рецензента за полезные комментарии

    High rate, fast timing Glass RPC for the high {\eta} CMS muon detectors

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    The HL-LHC phase is designed to increase by an order of magnitude the amount of data to be collected by the LHC experiments. To achieve this goal in a reasonable time scale the instantaneous luminosity would also increase by an order of magnitude up to 6.1034cm2s16.10^{34} cm^{-2} s^{-1} . The region of the forward muon spectrometer (η>1.6|{\eta}| > 1.6) is not equipped with RPC stations. The increase of the expected particles rate up to 2kHz/cm22 kHz/cm^{2} (including a safety factor 3) motivates the installation of RPC chambers to guarantee redundancy with the CSC chambers already present. The actual RPC technology of CMS cannot sustain the expected background level. The new technology that will be chosen should have a high rate capability and provides a good spatial and timing resolution. A new generation of Glass-RPC (GRPC) using low-resistivity (LR) glass is proposed to equip at least the two most far away of the four high η{\eta} muon stations of CMS. First the design of small size prototypes and studies of their performance in high-rate particles flux is presented. Then the proposed designs for large size chambers and their fast-timing electronic readout are examined and preliminary results are provided.Comment: 14 pages, 11 figures, Conference proceeding for the 2016 Resistive Plate Chambers and Related Detector

    Identification of alterations in the nucleotide sequence of the chromatin remodeling gene PBRM1 in clear cell renal cell carcinoma patients

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    Kidney cancer is a heterogeneous group of malignant tumors, the vast majority of which are renal cell carcinomas (RCC) of various morphological types, of which the most common is the clear cell renal cell carcinoma (ccRCC). Particular attention in the carcinogenesis of the ccRCC is given to a number of tumor suppressor genes located on the short arm of the third chromosome. One of these genes, which are inactivated in the case of ccRCC is the PBRM1 gene encoding the PBAF SWI/SNF subunit of the chromatin remodeling complex, BAF180. The PBRM1 gene is located on the short arm of the third chromosome in the 3p21 region near the von Hippel-Lindau gene (VHL), the mutation in which is the main event in the occurrence of ccRCC. The aim of our investigation is identification of changes in the nucleotide sequence of the PBRM1 tumor suppressor gene in patients with ccRCC. 210 pairs of DNA samples isolated from ccRCC tissue were studied. Analysis of changes in the nucleotide sequence of DNA was carried out by HRM analysis and direct sequencing. In the PBRM1 gene, two somatic mutations were found (c.233G>A (p.D45N) in exon 2, c.1675-1676delTC in exon 15) which were not described previously, and one known polymorphic variant rs17264436 (in exon 23). The frequency of detected mutations was 0.95 % of cases. Analysis of the allelic association for the polymorphic locus rs17264436 showed a statistically significant increase in the risk of developing advanced kidney cancer in carriers of allele rs17264436*A, which can be used in the development of prognostic marker panels. Perhaps the low frequency of mutations in the samples we studied is due to the fact that the inactivation of the PBRM1 gene takes place in other ways, and may also be due to the ethno-specificity of the studied group of patients

    Web-based monitoring tools for Resistive Plate Chambers in the CMS experiment at CERN

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    The Resistive Plate Chambers (RPC) are used in the CMS experiment at the trigger level and also in the standard offline muon reconstruction. In order to guarantee the quality of the data collected and to monitor online the detector performance, a set of tools has been developed in CMS which is heavily used in the RPC system. The Web-based monitoring (WBM) is a set of java servlets that allows users to check the performance of the hardware during data taking, providing distributions and history plots of all the parameters. The functionalities of the RPC WBM monitoring tools are presented along with studies of the detector performance as a function of growing luminosity and environmental conditions that are tracked over time

    Radiation background with the CMS RPCs at the LHC

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    The Resistive Plate Chambers (RPCs) are employed in the CMS Experiment at the LHC as dedicated trigger system both in the barrel and in the endcap. This article presents results of the radiation background measurements performed with the 2011 and 2012 proton-proton collision data collected by CMS. Emphasis is given to the measurements of the background distribution inside the RPCs. The expected background rates during the future running of the LHC are estimated both from extrapolated measurements and from simulation
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