Possible relations between arterial hypertension and cervical spine fibromyalgias (literature review)

The literature review analyses and systematises currently available information on fibromyalgia etiology and pathogenesis, hypertension classification and causes, and considers possible relationships between cervical fibromyalgia and hypertension. Statistical data on mortality in Ukraine related to cardiovascular diseases, including hypertension, are highlighted. A concise classification of arterial hypertension according to the International Classification of Diseases-10 (ICD-10) and the International Classification of Diseases-11 (ICD-11) is provided, and its pathogenesis (emission hypertension, resistance hypertension and hypervolemia) is outlined. Physiological relations between cervical spine and cardiovascular system are considered. The main diagnostic criteria for fibromyalgia classification and its development stages are described. Prevalence of fibromyalgia is identified and its forms are classified in accordance with ICD-11. The available data on the likely causes of fibromyalgia pain and any established mechanisms of fibromyalgia pathogenesis, including, but not limited to peripheral and central sensitisation, neurogenic inflammatory processes occurring in the disease-associated peripheral tissues, spinal cord and brain, as well as potential involvement of genetic, endocrine, psychopathological factors and sleep disorders in fibromyalgia development are discussed. The current formal criteria for fibromyalgia classification (revised in 2016), together with assessment of the main pharmacological and non-pharmacological fibromyalgia treatment methods and approaches based upon available published clinical trials outcomes are described. The main directions of fibromyalgia research are identified, and further prospective studies covering different relationship aspects between hypertension and cervical fibromyalgia are evaluated. Among the available literature sources, the only study of patients with comorbid fibromyalgia (fibromyalgia was diagnosed using 1990 American College of Rheumatology criteria and evaluated by Revised fibromyalgia impact questionnaire (FIQR)) and hypertension (blood pressure levels were assessed using the WHO protocol) has been reported. However, this group has only studied the dynamics of changes in cortisol, melatonin and serotonin blood levels, which accompany these pathologies, and these authors have found that fibromyalgia tender points’ quantity and FIQR scores are much higher in hypertensive patients with fibromyalgia in comparison with the rest, which has led them to the conclusion that hypertension prevalence in patients with fibromyalgia could be related to fibromyalgia severity. Thus, this thorough literature review demonstrates that clinical studies examining possible relationships between hypertension and cervical spine fibromyalgia are at lack and require further considerations

METHODOLOGICAL APPROACHES TO EVALUATING BEER AND NON-ALCOHOLIC PRODUCTS SHELF LIFE

The article discusses the relevance of developing methodological approaches to the beer and soft drinks accelerated aging method in the market. The controlled indicators selection principles, mainly affecting the quality of the finished product, and the basic equation describing the dependence of changes in indicators on the main temperature factor are given. Studies of the influence of various physical factors (temperatures in the range of 50–60 °C, UV-radiation), both individually and jointly, on the physicochemical and organoleptic characteristics of packaged water for various experimental versions did not show statistically significant changes in the normalized parameters of the basic salt and microelement composition investigated water during storage. The optimal mode of accelerated «aging» of packaged water at an elevated temperature (up to 60 °C) and UV-radiation was established. In the case of soft drinks, thermostating was used when changing the temperature regimes (heat 50 ± 2 °C / cold 6 ± 2 °C) at an exposure time of 30 days, which made it possible to observe a decrease in taste and aroma compared with the control, as well as a decrease in sweetness and the appearance of a slight plastic taste for non-carbonated drink. The influence a temperature regime change on brewing products, which cannot be estimated using the existing method due to the high turbidity, is shown.The article discusses the relevance of developing methodological approaches to the beer and soft drinks accelerated aging method in the market. The controlled indicators selection principles, mainly affecting the quality of the finished product, and the basic equation describing the dependence of changes in indicators on the main temperature factor are given. Studies of the influence of various physical factors (temperatures in the range of 50–60 °C, UV-radiation), both individually and jointly, on the physicochemical and organoleptic characteristics of packaged water for various experimental versions did not show statistically significant changes in the normalized parameters of the basic salt and microelement composition investigated water during storage. The optimal mode of accelerated «aging» of packaged water at an elevated temperature (up to 60 °C) and UV-radiation was established. In the case of soft drinks, thermostating was used when changing the temperature regimes (heat 50 ± 2 °C / cold 6 ± 2 °C) at an exposure time of 30 days, which made it possible to observe a decrease in taste and aroma compared with the control, as well as a decrease in sweetness and the appearance of a slight plastic taste for non-carbonated drink. The influence a temperature regime change on brewing products, which cannot be estimated using the existing method due to the high turbidity, is shown

Formation of metallic magnetic clusters in a Kondo-lattice metal: Evidence from an optical study

Magnetic materials are usually divided into two classes: those with localised magnetic moments, and those with itinerant charge carriers. We present a comprehensive experimental (spectroscopic ellipsomerty) and theoretical study to demonstrate that these two types of magnetism do not only coexist but complement each other in the Kondo-lattice metal, Tb2PdSi3. In this material the itinerant charge carriers interact with large localised magnetic moments of Tb(4f) states, forming complex magnetic lattices at low temperatures, which we associate with self-organisation of magnetic clusters. The formation of magnetic clusters results in low-energy optical spectral weight shifts, which correspond to opening of the pseudogap in the conduction band of the itinerant charge carriers and development of the low- and high-spin intersite electronic transitions. This phenomenon, driven by self-trapping of electrons by magnetic fluctuations, could be common in correlated metals, including besides Kondo-lattice metals, Fe-based and cuprate superconductors.Comment: 30 pages, 6 Figure

Preparation of crystalline Mg(OH)2 nanopowder from serpentinite mineral

In this paper we describe a route to produce crystalline Mg(OH)2 nanopowders from serpentinite ore distributed in the Halilovskiy array (Russia, Orenburg region). An efficient extraction route consisting of treatment on serpentinite in 40% HNO3 at 80 C followed by NH4OH titration for Mg(OH)2 precipitation was demonstrate

A method for production of phytomineralsorbent, physical and chemical properties of it, effect on the living systems and the quality of the livestock industry products

Numerous experimental studies have shown that the sorption-active substances can clarify the reservoir, soils, drinking municipal water from unwanted impurities with a sufficient degree of effectiveness; eliminate the potentially toxic for health chemicals of different chemical nature from human body. This is ensuring their using in the animal production practice, veterinary medicine and medicine. The main purpose and focus of this study are associated with the solution of problems of the maintaining physiological and biochemical status of live-stock animals. It provides their productivity and biological value of obtained product

Enzymatic treatment to increase extract yield from chlorella algae

Algae has shown to contain bioactive compounds which is of interest for researchers in different fields. Feasible extraction methods are essential for researchers to perform their experiments on those bioactive compounds and for industry for mass production. The use of enzymes to pre-treat algae before extraction lead to much better yield and higher quality extract [1].The authors state that there is no conflict of interest. This work was supported by the RFBR under Grants 17-03-00641 and 18-29-12129 mк, respectively, the Ministry of Education of the Russian Federation within the framework of the basic part of the state task, Project № 4.9514.2017/8.9 and the Program 211 of the Government of the Russian Federation № 02.A03.21.0006