15,844 research outputs found
Amorphous ice: Stepwise formation of very-high-density amorphous ice from low-density amorphous ice at 125 K
On compressing low-density amorphous ice (LDA) at 125 K up to 1.6 GPa, two distinct density steps accompanied by heat evolution are observable in pressure-density curves. Samples recovered to 77 K and 1 bar after the first and second steps show the x-ray diffraction pattern of high-density amorphous ice (HDA) and very HDA (VHDA), respectively. The compression of the once formed HDA takes place linearly in density up to 0.95 GPa, where nonlinear densification and HDA -> VHDA conversion is initiated. This implies a stepwise formation process LDA -> HDA -> VHDA at 125 K, which is to the best of our knowledge the first observation of a stepwise amorphous-amorphous-amorphous transformation sequence. We infer that the relation of HDA and VHDA is very similar to the relation between LDA and HDA except for a higher activation barrier between the former. We discuss the two options of thermodynamic versus kinetic origin of the phenomenon
New D1-D5-P geometries from string amplitudes
We derive the long range supergravity fields sourced by a D1-D5-P bound state
from disk amplitudes for massless closed string emission. We suggest that since
the parameter controlling the string perturbation expansion for this
calculation decreases with distance from the bound state, the resulting
asymptotic fields are valid even in the regime of parameters in which there is
a classical black hole solution with the same charges. The supergravity fields
differ from the black hole solution by multipole moments and are more general
than those contained within known classes of solutions in the literature,
whilst still preserving four supersymmetries. Our results support the
conjecture that the black hole solution should be interpreted as a
coarse-grained description rather than an exact description of the
gravitational field sourced by D1-D5-P bound states in this regime of
parameters.Comment: 48 pages, 2 figures, v2: typos correcte
Geometry of open strings ending on backreacting D3-branes
We investigate open string theory on backreacting D3-branes using a spacetime
approach. We study in detail the half-BPS supergravity solutions describing
open strings ending on D3-branes, in the near horizon of the D3-branes. We
recover quantitatively several non-trivial features of open string physics
including the appearance of D3-brane spikes, the polarization of fundamental
strings into D5-branes, and the Hanany-Witten effect. Finally we detail the
computation of the gravitational potential between two open strings, and
contrast it with the holographic computation of Wilson lines. We argue that the
D-brane backreaction has a large influence on the low-energy gravity, which may
lead to experimental tests for string theory brane-world scenarios.Comment: 64 pages, 20 figure
Intersecting black branes in strong gravitational waves
We consider intersecting black branes with strong gravitational waves
propagating along their worldvolume in the context of supergravity theories.
Both near-horizon and space-filling gravitational wave modes are included in
our ansatz. The equations of motion (originally, partial differential
equations) are shown to reduce to ordinary differential equations, which
include a Toda-like system. For special arrangements of intersecting black
branes, the Toda-like system becomes integrable, permitting a more thorough
analysis of the gravitational equations of motion.Comment: 17 pages; v2: cosmetic improvements, published versio
Early respiratory viral infections in infants with cystic fibrosis
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.Background
Viral infections contribute to morbidity in cystic fibrosis (CF), but the impact of respiratory viruses on the development of airway disease is poorly understood.
Methods
Infants with CF identified by newborn screening were enrolled prior to 4 months of age to participate in a prospective observational study at 4 centers. Clinical data were collected at clinic visits and weekly phone calls. Multiplex PCR assays were performed on nasopharyngeal swabs to detect respiratory viruses during routine visits and when symptomatic. Participants underwent bronchoscopy with bronchoalveolar lavage (BAL) and a subset underwent pulmonary function testing. We present findings through 8.5 months of life.
Results
Seventy infants were enrolled, mean age 3.1 ± 0.8 months. Rhinovirus was the most prevalent virus (66%), followed by parainfluenza (19%), and coronavirus (16%). Participants had a median of 1.5 viral positive swabs (range 0–10). Past viral infection was associated with elevated neutrophil concentrations and bacterial isolates in BAL fluid, including recovery of classic CF bacterial pathogens. When antibiotics were prescribed for respiratory-related indications, viruses were identified in 52% of those instances.
Conclusions
Early viral infections were associated with greater neutrophilic inflammation and bacterial pathogens. Early viral infections appear to contribute to initiation of lower airway inflammation in infants with CF. Antibiotics were commonly prescribed in the setting of a viral infection. Future investigations examining longitudinal relationships between viral infections, airway microbiome, and antibiotic use will allow us to elucidate the interplay between these factors in young children with CF
The influence of D-branes' backreaction upon gravitational interactions between open strings
We argue that gravitational interactions between open strings ending on
D3-branes are largely shaped by the D3-branes' backreaction. To this end we
consider classical open strings coupled to general relativity in Poincare AdS5
backgrounds. We compute the linear gravitational backreaction of a static
string extending up to the Poincare horizon, and deduce the potential energy
between two such strings. If spacetime is non-compact, we find that the
gravitational potential energy between parallel open strings is independent of
the strings' inertial masses and goes like 1/r at large distance r. If the
space transverse to the D3-branes is suitably compactified, a collective mode
of the graviton propagates usual four-dimensional gravity. In that case the
backreaction of the D3-branes induces a correction to the Newtonian potential
energy that violates the equivalence principle. The observed enhancement of the
gravitational attraction is specific to string theory; there is no similar
effect for point-particles.Comment: 28 pages, 7 figures. Typos corrected, minor addition
Intertwining Relations for the Deformed D1D5 CFT
The Higgs branch of the D1D5 system flows in the infrared to a
two-dimensional N=(4,4) SCFT. This system is believed to have an "orbifold
point" in its moduli space where the SCFT is a free sigma model with target
space the symmetric product of copies of four-tori; however, at the orbifold
point gravity is strongly coupled and to reach the supergravity point one needs
to turn on the four exactly marginal deformations corresponding to the blow-up
modes of the orbifold SCFT. Recently, technology has been developed for
studying these deformations and perturbing the D1D5 CFT off its orbifold point.
We present a new method for computing the general effect of a single
application of the deformation operators. The method takes the form of
intertwining relations that map operators in the untwisted sector before
application of the deformation operator to operators in the 2-twisted sector
after the application of the deformation operator. This method is
computationally more direct, and may be of theoretical interest. This line of
inquiry should ultimately have relevance for black hole physics.Comment: latex, 23 pages, 3 figure
Writing CFT correlation functions as AdS scattering amplitudes
We explore the Mellin representation of conformal correlation functions
recently proposed by Mack. Examples in the AdS/CFT context reinforce the
analogy between Mellin amplitudes and scattering amplitudes. We conjecture a
simple formula relating the bulk scattering amplitudes to the asymptotic
behavior of Mellin amplitudes and show that previous results on the flat space
limit of AdS follow from our new formula. We find that the Mellin amplitudes
are particularly useful in the case of conformal gauge theories in the planar
limit. In this case, the four point Mellin amplitudes are meromorphic functions
whose poles and their residues are entirely determined by two and three point
functions of single-trace operators. This makes the Mellin amplitudes the ideal
objects to attempt the conformal bootstrap program in higher dimensions.Comment: 23 pages + appendice
D1D5 microstate geometries from string amplitudes
We reproduce the asymptotic expansion of the D1D5 microstate geometries by
computing the emission amplitudes of closed string states from disks with mixed
D1D5 boundary conditions. Thus we provide a direct link between the
supergravity and D-brane descriptions of the D1D5 microstates at non-zero
string coupling. Microscopically, the profile functions characterizing the
microstate solutions are encoded in the choice of a condensate for the twisted
open string states connecting D1 and D5 branes.Comment: 21 pages; added reference
Holographic Approach to Regge Trajectory and Rotating D5 brane
We study the Regge trajectories of holographic mesons and baryons by
considering rotating strings and D5 brane, which is introduced as the baryon
vertex. Our model is based on the type IIB superstring theory with the
background of asymptotic . This background is dual to a
confining supersymmetric Yang-Mills theory (SYM) with gauge condensate,
, which determines the tension of the linear potential between the quark
and anti-quark. Then the slope of the meson trajectory () is given
by this condensate as at large spin . This
relation is compatible with the other theoretical results and experiments. For
the baryon, we show the importance of spinning baryon vertex to obtain a Regge
slope compatible with the one of and series. In both cases, mesons
and baryons, the trajectories are shifted to large mass side with the same
slope for increasing current quark mass.Comment: 28 pages, 7 figure
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