745 research outputs found

    Privacy Mining from IoT-based Smart Homes

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    Recently, a wide range of smart devices are deployed in a variety of environments to improve the quality of human life. One of the important IoT-based applications is smart homes for healthcare, especially for elders. IoT-based smart homes enable elders' health to be properly monitored and taken care of. However, elders' privacy might be disclosed from smart homes due to non-fully protected network communication or other reasons. To demonstrate how serious this issue is, we introduce in this paper a Privacy Mining Approach (PMA) to mine privacy from smart homes by conducting a series of deductions and analyses on sensor datasets generated by smart homes. The experimental results demonstrate that PMA is able to deduce a global sensor topology for a smart home and disclose elders' privacy in terms of their house layouts.Comment: This paper, which has 11 pages and 7 figures, has been accepted BWCCA 2018 on 13th August 201

    Rectification of Sabah Stilt House Using Shear Wall Subjected to Earthquake

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    A moderate earthquake with 6.0-magnitude hit Sabah in 2015 especially in Ranau, Sabah has been labelled as one of the most powerful earthquakes ever in Malaysia. Numerous buildings in Sabah have become defective with the severity level of damages as absolute (non-repairable) in the RC beam-column joints and soft-storey structures. Seismic design and construction requirements were not considered in most buildings in Sabah. Hence, this research is to investigate how to mitigate the effect of earthquake on the low-rise building using a more practical and economical method. A stilt house model is developed using ABAQUS software to determine the behaviour of the stilt, low-rise building subjected to earthquake by constructing shear wall at the short columns support. There are 4 models constructed namely, frame model without shear wall (W1), with shear wall of 100mm (W2), 300mm (W3) and 500mm (W4). The results of seismic response are evaluated and compared. Different length of shear wall affects the displacement and stress of the frame model. As shear wall length increases, the displacement, stress at columns and stress at walls decreases. Thus, adding a shear wall can be used to retrofit stilt houses and a credible way to mitigate damage due to earthquake load for new houses along hill slope

    Rectification of Sabah Stilt House Using Shear Wall Subjected to Earthquake

    Get PDF
    A moderate earthquake with 6.0-magnitude hit Sabah in 2015 especially in Ranau, Sabah has been labelled as one of the most powerful earthquakes ever in Malaysia. Numerous buildings in Sabah have become defective with the severity level of damages as absolute (non-repairable) in the RC beam-column joints and soft-storey structures. Seismic design and construction requirements were not considered in most buildings in Sabah. Hence, this research is to investigate how to mitigate the effect of earthquake on the low-rise building using a more practical and economical method. A stilt house model is developed using ABAQUS software to determine the behaviour of the stilt, low-rise building subjected to earthquake by constructing shear wall at the short columns support. There are 4 models constructed namely, frame model without shear wall (W1), with shear wall of 100mm (W2), 300mm (W3) and 500mm (W4). The results of seismic response are evaluated and compared. Different length of shear wall affects the displacement and stress of the frame model. As shear wall length increases, the displacement, stress at columns and stress at walls decreases. Thus, adding a shear wall can be used to retrofit stilt houses and a credible way to mitigate damage due to earthquake load for new houses along hill slope

    The effect of dandelion hydro-alcoholic extract and its active constituent on radiosensitivity of glioblastoma cancer cells: an in vitro study

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    OBJECTIVE: Radiation therapy is one of the many methods that are used to cure cancers. Considering the high resistance of cancer cells to radiation therapy and its many side effects, and considering that in recent years the high medicinal potential of plants has been noticed, the aim of this study is to investigate the effects of the dandelion hydro-alcoholic extract and its active constituent on the radiation therapy cytotoxic effect in glioblastoma cancer cells. MATERIALS AND METHODS: After treatment with extract and taraxasterol, the cell viability was evaluated by 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide assay. Then the effect of the combination of extract and taroxasterol with ionizing radiation was tested. The apoptosis cell death was investigated by diphenylamine assay and real-time technic. RESULTS: After treatment with extract and taraxasterol, cell viability was decreased in a dose-dependent manner. The extract and taraxasterol increased the sensitivity of cells to ionizing radiation. In addition, after treatment with the extract and taraxasterol, the amount of apoptosis induced by ionizing radiation in the cells increased. After treatment with extract, taraxasterol and ionizing radiation, the expression of Bax and p53 increased and the expression of Bcl-2 decreased. CONCLUSIONS: Using the dandelion along with radiation therapy may show a better response to treatment in glioblastoma patients

    The cytotoxic and migrastatic potentials of Allium Jesdianum hydroalcoholic extract on glioblastoma multiforme cell line model

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    OBJECTIVE: Glioblastoma multiforme is one of the most malignant types of central nervous system tumors and temozolomide (TMZ) is currently used as a standard treatment for this type of cancer. However, resistance to temozolomide is a problem in the successful treatment. Plants and herbs are potential sources of cancer therapeutics. This study aimed at evaluating the effect of Allium Jesdianum (AJ) hydroalcoholic extract on glioblastoma multiforme cells. MATERIALS AND METHODS: The plant material was purchased and extracted. The cell line was treated with extract for 24, 48, and 72 hr. Cell viability was assessed by trypan blue staining, MTT assay, and lactate dehydrogenase activity measurement. Tumor invasion potential was evaluated by cell migration, invasion, and adhesion tests. Real-time PCR was used to assess the changes in the expression pattern of genes involved in cancer invasion. RESULTS: Extract treatment caused a concentration- and time-dependent decrease in cell survival. Also, a decrease in cell migration, invasion and adhesion potential and the expression of metalloproteinases 2 and 9 in cells was observed after treatment. CONCLUSIONS: Allium Jesdianum showed promising anti-cancer activity in glioblastoma multiforme cells

    Praeorbitolina claveli n.sp. (foraminifère benthique) de l'Aptien inférieur sensu lato (Bédoulien) du centre de l'Iran

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    Un nouveau foraminifère orbitolinidé, Praeorbitolina claveli n.sp., est identifié dans l'Aptien inférieur (Bédoulien) de l'Iran central. Il se caractérise par un appareil embryonnaire constitué d'une zone subembryonnaire subdivisée ainsi que d'une déutéroconque. L'association d'orbitolinidés d'âge Barrémien-Aptien de cette région présente un caractère typiquement nord-téthysien (e.g., "association à Valserina" de CHERCHI et SCHROEDER, 1973).The new orbitolinid foraminifer, Praeorbitolina claveli n.sp., is described from the Lower Ap-tian (Bedoulian) of Central Iran. It is characterized by an eccentric embryonic apparatus displaying both a subdivided subembryonic zone and a deuteroconch. The Barremian-Aptian orbitolinid association of this area has a typical northern Tethyan character (e.g., "association à Valserina" of CHERCHI and SCHROEDER, 1973)

    Authentication of butter from lard adulteration using high-resolution of nuclear magnetic resonance spectroscopy and high-performance liquid chromatography

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    Food authentication is an interesting issue for all parties in the food industry, including the fats and oils industry. Some unethical players try to blend high-quality foods, such as butter, with lower ones like lard, therefore, the analytical methods capable of analyzing the adulteration practices must be developed. This study used proton nuclear magnetic resonance spectroscopy in combination with high-performance liquid chromatography for the authentication of butter from lard adulteration. The identification of triacylglycerol composition of lard as a chemical marker for halal authentication is analyzed using high-performance liquid chromatography and high resolution nuclear magnetic resonance spectroscopy. The suitability of proton nuclear magnetic resonance provides a high-performance approach for determination butter adulterated with lard in their entirety of all proton bearing components. Peaks in the region of 2.60–2.84 ppm show special characteristics only present in lard. Only lard has its own unique characteristics which only polyunsaturated fatty acids would give signals 7 at δ 2.63, that corresponded to the chemical shift of the double-allylic methylene protons. In the same way, the intensity of signal at 2.63 ppm, due to methylenic protons in a position α to two double bonds, that is to say, due to the linoleic group. Furthermore, we also correlate some signals between 1H and 13C-NMR spectra for the confirmation of signals

    A five-year retrospective review of snakebite patients admitted to a tertiary university hospital in Malaysia

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    BACKGROUND Although the majority of the snakebite cases in Malaysia are due to non-venomous snakes, venomous bites cause significant morbidity and mortality if treatment measures, especially ant-venom therapy, are delayed. METHODS To determine the demographic characteristics, we conducted a retrospective study on all snakebite patients admitted to the Emergency Department of Hospital Universiti Sains Malaysia (HUSM) from January 2006 to December 2010. RESULTS In the majority of the 260 cases that we found (138 cases or 52.9%), the snake species was unidentified. The most common venomous snakebites among the identified species were caused by cobras (52 cases or 20%). Cobra bites are significantly more likely to result in severe envenomation compared to non-cobra bites. Post hoc analysis also showed that cobra bite patients are significantly less likely to have complete recovery than non-cobra bite patients (48 cases, 75.0% vs. 53 cases, 94.6%; p = 0.003) and more likely to result in local gangrene (11 cases, 17.2% vs. 3 cases, 5.4%; p = 0.044). CONCLUSION Cobra bites are significantly more likely to result in severe envenomation needing anti-venom administration and more likely to result in local gangrene, and the patients are significantly less likely to have complete recovery than those with non-cobra bites

    Single cell phenotyping reveals heterogeneity among haematopoietic stem cells following infection.

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    The haematopoietic stem cell (HSC) niche provides essential micro-environmental cues for the production and maintenance of HSCs within the bone marrow. During inflammation, haematopoietic dynamics are perturbed, but it is not known whether changes to the HSC-niche interaction occur as a result. We visualise HSCs directly in vivo, enabling detailed analysis of the 3D niche dynamics and migration patterns in murine bone marrow following Trichinella spiralis infection. Spatial statistical analysis of these HSC trajectories reveals two distinct modes of HSC behaviour: (i) a pattern of revisiting previously explored space, and (ii) a pattern of exploring new space. Whereas HSCs from control donors predominantly follow pattern (i), those from infected mice adopt both strategies. Using detailed computational analyses of cell migration tracks and life-history theory, we show that the increased motility of HSCs following infection can, perhaps counterintuitively, enable mice to cope better in deteriorating HSC-niche micro-environments following infection

    Rectification of Sabah stilt house using shear wall subjected to earthquake

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    A moderate earthquake with 6.0-magnitude hit Sabah in 2015 especially in Ranau, Sabah has been labelled as one of the most powerful earthquakes ever in Malaysia. Numerous buildings in Sabah have become defective with the severity level of damages as absolute (non-repairable) in the RC beam-column joints and softstorey structures. Seismic design and construction requirements were not considered in most buildings in Sabah. Hence, this research is to investigate how to mitigate the effect of earthquake on the low-rise building using a more practical and economical method. A stilt house model is developed using ABAQUS software to determine the behaviour of the stilt, low-rise building subjected to earthquake by constructing shear wall at the short columns support. There are 4 models constructed namely, frame model without shear wall (W1), with shear wall of 100mm (W2), 300mm (W3) and 500mm (W4). The results of seismic response are evaluated and compared. Different length of shear wall affects the displacement and stress of the frame model. As shear wall length increases, the displacement, stress at columns and stress at walls decreases. Thus, adding a shear wall can be used to retrofit stilt houses and a credible way to mitigate damage due to earthquake load for new houses along hill slopes
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