1,875 research outputs found
Senile plaque calcification of the lamina circumvoluta medullaris in Alzheimer's disease
Vascular calcification is a common phenomenon in the elderly, predominantly appearing in the basal ganglia and in the lamina circumvoluta medullaris of the hippocampus. Calcifications are not an inherent feature of Alzheimer's disease. On the other hand, a rare presenile type of dementia with symmetrical Fahr-type calcifications and numerous neurofibrillary tangles without senile plaques has been described by Kosaka in 1994 and was termed "diffuse neurofibrillary tangles with calcification" (DNTC). We here report a case of Alzheimer's disease with calcifications both in the basal ganglia and in the lamina circumvoluta medullaris of the hippocampus, differing from DNTC by the presence of senile plaques. The calcifications in the hippocampus were not only vascular in nature but also covered amyloid-β- and phosphorylated tau-positive plaque-like structures that were linearly arranged along the dentate fascia in the CA1 sector, an unusual finding of pathogenetic interest
Expanding Economic Opportunity for Young Men and Boys of Color through Employment and Training
Young men of color have long experienced lower earnings and higher unemployment compared to young white men. Many factors have contributed to these negative outcomes: persistent discrimination, hiring practices of employers, geographic and social isolation, substandard secondary education, lack of career and postsecondary educational guidance, inadequate career and technical education, and higher incarceration rates. This paper focuses on promising strategies for improving the labor market outcomes of low-income young men of color. It outlines an employment-focused approach to improving economic opportunities and outcomes for these young men, highlighting potential policy, system and institutional reforms as well as program investments
Manifestation of anisotropy persistence in the hierarchies of MHD scaling exponents
The first example of a turbulent system where the failure of the hypothesis
of small-scale isotropy restoration is detectable both in the `flattening' of
the inertial-range scaling exponent hierarchy, and in the behavior of odd-order
dimensionless ratios, e.g., skewness and hyperskewness, is presented.
Specifically, within the kinematic approximation in magnetohydrodynamical
turbulence, we show that for compressible flows, the isotropic contribution to
the scaling of magnetic correlation functions and the first anisotropic ones
may become practically indistinguishable. Moreover, skewness factor now
diverges as the P\'eclet number goes to infinity, a further indication of
small-scale anisotropy.Comment: 4 pages Latex, 1 figur
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Effects of solar wind magnetosphere coupling recorded at different geomagnetic latitudes: Separation of directly-driven and storage/release systems
The effect on geomagnetic activity of solar wind speed, compared with that of the strength of the interplanetary magnetic field, differs with geomagnetic latitude. In this study we construct a new index based on monthly standard deviations in the H-component of the geomagnetic field for all geomagnetic latitudes. We demonstrate that for this index the response at auroral regions correlates best with interplanetary coupling functions which include the solar wind speed while mid- and low-latitude regions respond to variations in the interplanetary magnetic field strength. These results are used to isolate the responsible geomagnetic current systems
Deformed two center shell model
A highly specialized two-center shell model has been developed accounting for
the splitting of a deformed parent nucleus into two ellipsoidaly deformed
fragments. The potential is based on deformed oscillator wells in direct
correspondance with the shape change of the nuclear system. For the first time
a potential responsible for the necking part between the fragments is
introduced on potential theory basis. As a direct consequence, spin-orbit {\bf
ls} and {\bf l} operators are calculated as shape dependent. Level scheme
evolution along the fission path for pairs of ellipsoidaly deformed fragments
is calculated. The Strutinsky method yields the shell corrections for different
mass asymmetries from the superheavy nucleus 122 and Cf all
along the splitting process.Comment: 32 pages, 8 figure
Dynamics of Line-Driven Winds from Disks in Cataclysmic Variables. I. Solution Topology and Wind Geometry
We analyze the dynamics of 2-D stationary, line-driven winds from accretion
disks in cataclysmic variable stars. The driving force is that of line
radiation pressure, in the formalism developed by Castor, Abbott & Klein for O
stars. Our main assumption is that wind helical streamlines lie on straight
cones. We find that the Euler equation for the disk wind has two eigenvalues,
the mass loss rate and the flow tilt angle with the disk. Both are calculated
self-consistently. The wind is characterized by two distinct regions, an outer
wind launched beyond four white dwarf radii from the rotation axis, and an
inner wind launched within this radius. The inner wind is very steep, up to 80
degrees with the disk plane, while the outer wind has a typical tilt of 60
degrees. In both cases the ray dispersion is small. We, therefore, confirm the
bi-conical geometry of disk winds as suggested by observations and kinematical
modeling. The wind collimation angle appears to be robust and depends only on
the disk temperature stratification. The flow critical points lie high above
the disk for the inner wind, but close to the disk photosphere for the outer
wind. Comparison with existing kinematical and dynamical models is provided.
Mass loss rates from the disk as well as wind velocity laws are discussed in a
subsequent paper.Comment: 21 pages, 10 Postscript figures; available also from
http://www.pa.uky.edu/~shlosman/publ.html. Astrophysical Journal, submitte
The influence of constrictivity on the effective transport properties of porous layers in electrolysis and fuel cells
The aim of the present investigation is to define microstructure parameters, which control the effective transport properties in porous materials for energy technology. Recent improvements in 3D-imaging (FIB-nanotomography, synchrotron X-ray tomography) and image analysis (skeletonization and graph analysis, transport simulations) open new possibilities for the study of microstructure effects. In this study, we describe novel procedures for a quantitative analysis of constrictivity, which characterizes the so-called bottleneck effect. In a first experimental part, methodological tests are performed using a porous (La,Sr)CoO3 material (SOFC cathode). The tests indicate that the proposed procedure for quantitative analysis of constrictivity gives reproducible results even for samples with inhomogeneous microstructures (cracks, gradient of porosity). In the second part, 3D analyses are combined with measurements of ionic conductivity by impedance spectroscopy. The investigations are preformed on membranes of electrolysis cells with porosities between 0.27 and 0.8. Surprisingly, the tortuosities remain nearly constant (1.6) for the entire range of porosity. In contrast, the constrictivities vary strongly and correlate well with the measured transport resistances. Hence, constrictivity represents the dominant microstructure parameter, which controls the effective transport properties in the analysed membrane materials. An empirical relationship is then derived for the calculation of effective transport properties based on phase volume fraction, tortuosity, and constrictivit
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