1,673 research outputs found

    Image-Optimized Coronal Magnetic Field Models

    Full text link
    We have reported previously on a new method we are developing for using image-based information to improve global coronal magnetic field models. In that work we presented early tests of the method which proved its capability to improve global models based on flawed synoptic magnetograms, given excellent constraints on the field in the model volume. In this follow-up paper we present the results of similar tests given field constraints of a nature that could realistically be obtained from quality white-light coronagraph images of the lower corona. We pay particular attention to difficulties associated with the line-of-sight projection of features outside of the assumed coronagraph image plane, and the effect on the outcome of the optimization of errors in localization of constraints. We find that substantial improvement in the model field can be achieved with this type of constraints, even when magnetic features in the images are located outside of the image plane

    The First Ground Level Enhancement Event of Solar Cycle 24: Direct Observation of Shock Formation and Particle Release Heights

    Full text link
    We report on the 2012 May 17 Ground Level Enhancement (GLE) event, which is the first of its kind in Solar Cycle 24. This is the first GLE event to be fully observed close to the surface by the Solar Terrestrial Relations Observatory (STEREO) mission. We determine the coronal mass ejection (CME) height at the start of the associated metric type II radio burst (i.e., shock formation height) as 1.38 Rs (from the Sun center). The CME height at the time of GLE particle release was directly measured from a STEREO image as 2.32 Rs, which agrees well with the estimation from CME kinematics. These heights are consistent with those obtained for cycle-23 GLEs using back-extrapolation. By contrasting the 2012 May 17 GLE with six other non-GLE eruptions from well-connected regions with similar or larger flare size and CME speed, we find that the latitudinal distance from the ecliptic is rather large for the non-GLE events due to a combination of non-radial CME motion and unfavorable solar B0 angle, making the connectivity to Earth poorer. We also find that the coronal environment may play a role in deciding the shock strength.Comment: 16 pages, 4 figures, 1 tabl

    Component-resolved diagnosis of pollen allergy based on skin testing with profilin, polcalcin and lipid transfer protein pan-allergens

    Full text link
    BACKGROUND Allergy diagnosis needs to be improved in patients suffering from pollen polysensitization due to the existence of possible confounding factors in this type of patients. OBJECTIVE To evaluate new diagnostic strategies by comparing skin responses to pan-allergens and conventional allergenic extracts with specific IgE (sIgE) to purified allergen molecules. METHODS One thousand three hundred and twenty-nine pollen-allergic patients were diagnosed by a combination of an in vitro method with a panel of 13 purified allergens, including major allergens and pan-allergens, using a high-capacity screening technology (ADVIA-Centaur®) and skin prick test (SPT) to pan-allergens and conventional extracts. RESULTS There was a high concordance (κ index) between in vitro (sIgE to major allergens) and in vivo (SPT to conventional extracts) methods in patients who were not sensitized to pan-allergens, but SPT with conventional extracts failed to diagnose patients with sensitization to pan-allergens. In patients who were simultaneously sensitized to polcalcins and profilins, there was a duplication both in the number of sensitizations to major allergens and in the years of disease evolution. There was a statistical association between sensitization to profilins and/or lipid transfer proteins and food allergy (P<0.0001). CONCLUSION The novel diagnostic strategy has proven to be a valuable tool in daily clinical practice. Introduction of routine SPT to pan-allergens is a simple and feasible way of improving diagnostic efficacy. Patients sensitized to pan-allergens should be tested by an adequate panel of allergenic molecules in order to identify the allergens that are responsible for the allergic disease

    Evolutionary dynamics of insertion sequences in relation to the evolutionary histories of the chromosome and symbiotic plasmid genes of Rhizobium etli populations

    Get PDF
    Insertion sequences (IS) are mobile genetic elements that are distributed in many prokaryotes. In particular, in the genomes of the symbiotic nitrogen-fixing bacteria collectively known as rhizobia, IS are fairly abundant in plasmids or chromosomal islands that carry the genes needed for symbiosis. Here, we report an analysis of the distribution and genetic conservation of the IS found in the genome of Rhizobium etli CFN42 in a collection of 87 Rhizobium strains belonging to populations with different geographical origins. We used PCR to generate presence/absence profiles of the 39 IS found in R. etli CFN42 and evaluated whether the IS were located in consistent genomic contexts. We found that the IS from the symbiotic plasmid were frequently present in the analyzed strains, whereas the chromosomal IS were observed less frequently. We then examined the evolutionary dynamics of these strains based on a population genetic analysis of two chromosomal housekeeping genes (glyA and dnaB) and three symbiotic sequences (nodC and the two IS elements). Our results indicate that the IS contained within the symbiotic plasmid have a higher degree of genomic context conservation, lower nucleotide diversity and genetic differentiation, and fewer recombination events than the chromosomal housekeeping genes. These results suggest that the R. etli populations diverged recently in Mexico, that the symbiotic plasmid also had a recent origin, and that the IS elements have undergone a process of cyclic infection and expansion

    Coexistence of Self-Organized Criticality and Intermittent Turbulence in the Solar Corona

    Full text link
    An extended data set of extreme ultraviolet images of the solar corona provided by the SOHO spacecraft are analyzed using statistical methods common to studies of self-organized criticality (SOC) and intermittent turbulence (IT). The data exhibits simultaneous hallmarks of both regimes, namely power law avalanche statistics as well as multiscaling of structure functions for spatial activity. This implies that both SOC and IT may be manifestations of a single complex dynamical process entangling avalanches of magnetic energy dissipation with turbulent particle flows.Comment: 4 pages, 4 figure

    Evaluation of the curvature ductility ratio of a circular cross-section of concrete reinforced with GFRP bars

    Get PDF
    The present study deals with the use of fiberglass reinforced polymer bars (GFRP) as a replacement for the common steel of a reinforced concrete circular pile, in order to avoid the corrosion of durability of reinforcing bars and thus improve them. The comparative analysis was carried out between a pile reinforced with GFRP and another with steel, where the ductility was evaluated by obtaining moment-curvature diagram. As a result, said idealized moment-curvature diagrams and ductility indices are presented, concluding the ductility of the section reinforced with GFRP in 20% more than that of steel

    PIN36 THE ECONOMIC IMPACT OF MARAVIROC FOR ANTIRETROVIRAL TREATMENT-EXPERIENCED HIV-INFECTED INDIVIDUALS IN MEXICO

    Get PDF
    • …
    corecore