First tests of a Micromegas TPC in a magnetic field

Talk given by P. ColasSince the summer of 2003, a large Micromegas TPC prototype (1000 channels, 50 cm drift, 50 cm diameter) has been operated in a 2T superconducting magnet at Saclay. A description of this apparatus and first results from cosmic ray tests are presented. Additional measurements using simpler detectors with a laser source, an X-ray gun and radio-active sources are discussed. Drift velocity and gain measurements, electron attachment and aging studies for a Micromegas TPC are presented. In particular, using simulations and measurements, it is shown that an $Argon-CF_4$ mixture is optimal for operation at a future Linear Collider

Component-resolved diagnosis of pollen allergy based on skin testing with profilin, polcalcin and lipid transfer protein pan-allergens

BACKGROUND Allergy diagnosis needs to be improved in patients suffering from pollen polysensitization due to the existence of possible confounding factors in this type of patients. OBJECTIVE To evaluate new diagnostic strategies by comparing skin responses to pan-allergens and conventional allergenic extracts with specific IgE (sIgE) to purified allergen molecules. METHODS One thousand three hundred and twenty-nine pollen-allergic patients were diagnosed by a combination of an in vitro method with a panel of 13 purified allergens, including major allergens and pan-allergens, using a high-capacity screening technology (ADVIA-Centaur®) and skin prick test (SPT) to pan-allergens and conventional extracts. RESULTS There was a high concordance (κ index) between in vitro (sIgE to major allergens) and in vivo (SPT to conventional extracts) methods in patients who were not sensitized to pan-allergens, but SPT with conventional extracts failed to diagnose patients with sensitization to pan-allergens. In patients who were simultaneously sensitized to polcalcins and profilins, there was a duplication both in the number of sensitizations to major allergens and in the years of disease evolution. There was a statistical association between sensitization to profilins and/or lipid transfer proteins and food allergy (P<0.0001). CONCLUSION The novel diagnostic strategy has proven to be a valuable tool in daily clinical practice. Introduction of routine SPT to pan-allergens is a simple and feasible way of improving diagnostic efficacy. Patients sensitized to pan-allergens should be tested by an adequate panel of allergenic molecules in order to identify the allergens that are responsible for the allergic disease

Micromegas in a Bulk

In this paper we present a novel way to manufacture the bulk Micromegas detector. A simple process based on the PCB (Printed Circuit Board) technology is employed to produce the entire sensitive detector. Such fabrication process could be extended to very large area detectors made by the industry. The low cost fabrication together with the robustness of the electrode materials will make it extremely attractive for several applications ranging from particle physics and astrophysics to medicineComment: 6 pages, 4 figure

Ultra low energy results and their impact to dark matter and low energy neutrino physics

We present ultra low energy results taken with the novel Spherical Proportional Counter. The energy threshold has been pushed down to about 25 eV and single electrons are clearly collected and detected. To reach such performance low energy calibration systems have been successfully developed: - A pulsed UV lamp extracting photoelectrons from the inner surface of the detector - Various radioactive sources allowing low energy peaks through fluorescence processes. The bench mark result is the observation of a well resolved peak at 270 eV due to carbon fluorescence which is unique performance for such large-massive detector. It opens a new window in dark matter and low energy neutrino search and may allow detection of neutrinos from a nuclear reactor or from supernova via neutrino-nucleus elastic scatteringComment: 14 pages,16 figure

Dark matter directional detection with MIMAC

MiMac is a project of micro-TPC matrix of gaseous (He3, CF4) chambers for direct detection of non-baryonic dark matter. Measurement of both track and ionization energy will allow the electron-recoil discrimination, while access to the directionnality of the tracks will open a unique way to distinguish a geniune WIMP signal from any background. First reconstructed tracks of 5.9 keV electrons are presented as a proof of concept.Comment: 4 pages, proc. of the 44th Rencontres De Moriond: Electroweak Interactions And Unified Theories, 7-14 Mar 2009, La Thuile, Ital

Impact of minority concentration on fundamental (H)D ICRF heating performance in JET-ILW

ITER will start its operation with non-activated hydrogen and helium plasmas at a reduced magnetic field of B-0 = 2.65 T. In hydrogen plasmas, the two ion cyclotron resonance frequency (ICRF) heating schemes available for central plasma heating (fundamental H majority and 2nd harmonic He-3 minority ICRF heating) are likely to suffer from relatively low RF wave absorption, as suggested by numerical modelling and confirmed by previous JET experiments conducted in conditions similar to those expected in ITER's initial phase. With He-4 plasmas, the commonly adopted fundamental H minority heating scheme will be used and its performance is expected to be much better. However, one important question that remains to be answered is whether increased levels of hydrogen (due to e. g. H pellet injection) jeopardize the high performance usually observed with this heating scheme, in particular in a full-metal environment. Recent JET experiments performed with the ITER-likewall shed some light onto this question and the main results concerning ICRF heating performance in L-mode discharges are summarized here

Spatial Resolution of a Micromegas-TPC Using the Charge Dispersion Signal

The Time Projection Chamber (TPC) for the International Linear Collider will need to measure about 200 track points with a resolution close to 100 $\mu$m. A Micro Pattern Gas Detector (MPGD) readout TPC could achieve the desired resolution with existing techniques using sub-millimeter width pads at the expense of a large increase in the detector cost and complexity. We have recently applied a new MPGD readout concept of charge dispersion to a prototype GEM-TPC and demonstrated the feasibility of achieving good resolution with pads similar in width to the ones used for the proportional wire TPC. The charge dispersion studies were repeated with a Micromegas TPC amplification stage. We present here our first results on the Micromegas-TPC resolution with charge dispersion. The TPC resolution with the Micromegas readout is compared to our earlier GEM results and to the resolution expected from electron statistics and transverse diffusion in a gaseous TPC.Comment: 5 pages, 8 figures, to appar in the Proceedings of the 2005 International Linear Collider Workshop (LCWS05), Stanford, 18-22 March 200