A secure data outsourcing scheme based on Asmuth – Bloom secret sharing

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Data outsourcing is an emerging paradigm for data management in which a database is provided as a service by third-party service providers. One of the major benefits of offering database as a service is to provide organisations, which are unable to purchase expensive hardware and software to host their databases, with efficient data storage accessible online at a cheap rate. Despite that, several issues of data confidentiality, integrity, availability and efficient indexing of users’ queries at the server side have to be addressed in the data outsourcing paradigm. Service providers have to guarantee that their clients’ data are secured against internal (insider) and external attacks. This paper briefly analyses the existing indexing schemes in data outsourcing and highlights their advantages and disadvantages. Then, this paper proposes a secure data outsourcing scheme based on Asmuth–Bloom secret sharing which tries to address the issues in data outsourcing such as data confidentiality, availability and order preservation for efficient indexing

Applications of Molecular Diagnostic Techniques for Infectious Diseases

Diagnosis is concerned with identifying the cause of a disease or precise and consistent outcomes that are results of direct or indirect actions, reactions and interactions between the cause of a disease and the host. That outcome, if accurate, would help the clinician in disease management, or the epidemiologist in identifying trends of diseases or the administrator in policy and decision making. Traditionally, infectious disease diagnosis involves identifying the causative agents of infectious diseases through the direct examination, culture and often immunological tests on clinical specimens. The traditional diagnostic  techniques have varied sensitivities and specificities which influence their choice and applicability in a particular setting for the diagnosis of infectious diseases. However, the limitations of many traditional techniques particularly low specificity and long turnaround time often necessitate initiation of treatment before results are made available. Molecular diagnostic techniques involve a variety of techniques that explore the use of nucleic acid molecules for the identification of a particular pathogenic organism. These techniques include nucleic acid-based typing system, nucleic acid analysis without amplification, polymerase chain reaction (PCR) and other nucleic acid amplification techniques. Applications of molecular detection methods for infectious diseases have resolved many of the problems of the traditional diagnostic techniques, due to their exquisite sensitivity and specificity that allow the accurate and timely detection of very small numbers of organisms. This paper examines the principles and applications of molecular biology techniques in the identification of the causative agents of  infectious  diseases either in a routine setting or as research tools.Keywords: Infectious diseases, Molecular diagnosis, Polymerase Chain Reactio

Cloud-based online social network

International audienceOnline social media network has become part of human life by transforming the way users create new social relations or relate with family and friends. Online social network (OSN) has drastically increased the rate at which people interact with each other by simplifying the means of communication. However, privacy is raising a serious concern. All user generated data within the OSN system need to be protected against unauthorized friends or hackers or even against the provider of OSN. Many research works are going on to encounter the privacy issues in OSN. This paper analyses the limitations of the recent work being done in this field and proposes an efficient abstract solution to them

Nanocomposites transformed from polystyrene waste/antimony, barium and nickel oxides nanoparticles with improved thermal and electrical properties

In this experiment, the oxide nanoparticles were synthesized via chemical precipitation and the nanocomposites were produced using in situ polymerization method with varying nanoparticles contents ranged from 0.1 g to 1.0 g for electrical conductivity and from 0.05 g to 0.25 g for thermal conductivity. The electrical and thermal conductivities of nanocomposites were investigated and compared with the values obtained for untreated polystyrene. It was observed that the electrical and thermal properties were higher for the nanocomposites and increase with increasing nanoparticle concentrations in the samples. It can be observed that nanocomposite containing NiO nanoparticles gave a better electrical and thermal conductivity followed by nanocomposite containing BaO nanoparticles and nanocomposite containing Sb2O3 nanoparticles respectively. It can also be observed that nanocomposite containing NiO nanoparticle showed increase in rate of heat transfer from 1.60 W to 2.60 W, while nanocomposite containing BaO nanoparticles recorded increase in rate of heat transfer from 1.40 W to 2.45 W and nanoomposite containing Sb2O3 nanoparticle showed increase in rate of heat transfer from 1.07 W to 2.21 W, as concentration of nanoparticles increased from 0.05 g to 0.25 g respectively. Conclusively, with these results, the nanocomposite containing NiO nanoparticles gave a better thermal and electrical conductivity by having a better conducting filler network inside the matrix than nanocomposite containing BaO nanoparticles and nanocomposite containing Sb2O3 nanoparticles. It is recommended that during the production of polymer nanocomposite, PS/NiO, PS/BaO and PS/Sb2O3 nanocomposites could be used in electrically conductive devices as well as suitable materials for heat transfer applications

Effects of Herbal “Gadagi” Tea on Some Cardiovascular Risk Factors in Experimental Rats

Cardiovascular disease (CVD) remains a major cause of mortality worldwide in spite of the recent advances in medical and surgical treatment. Twenty Wistar albino rats were divided into Four (4) equal groups each comprising of five (5) members. The groups (A, B & C) were orally administered with prepared Herbal/Garlic “Gadagi” Tea, at low dose (3 mg/kg), standard dose (6 mg/kg) and high dose (12 mg/kg) respectively. Group D served as normal control. After two weeks of Herbal/Garlic “Gadagi” tea administration, all the 20 Wistar albino rats were sacrificed by decapitation and their blood samples were collected and used for biochemical analyses. Total Cholesterol (TC), HDL-cholesterol, LDL-Cholesterol, Triglycerides, Sodium, Potassium, AST, CK, and LDH were analysed using standard methods. There was a significant increase (P < 0.05) in the levels of TC, LDL-Cholesterol, Potassium and CK in group C compared to control and significant decrease (P<0.05) in HDL-Cholesterol in group A compared to normal. Dose- dependent increases were observed (P<0.05) in TC, LDL-cholesterol, Triglycerides and LDH at 6mg/kg and 12mg/kg doses; Potassium at 3mg/kg and 6mg/kg doses and at 6mg/kg and 12mg/kg doses; CK at 3mg/kg and 6mg/kg doses respectively. Generally, the current research suggests that herbal/Garlic “Gadagi” tea might be a risk factor of cardiovascular diseases, and may be toxic to both the heart and peripheral vascular tissues at doses beyond 6 mg/kg. Keywords: Gadagi, cardiovascular diseases, herbal medicine, tissue damage marker

Establishing convergent validity of a medication literacy assessment instrument for use within the Nigerian setting

Purpose: To establish convergent validity of a previously designed medication literacy instrument for use in Nigeria. Methods: A cross-sectional study was conducted in Zaria, Kaduna State from May to August 2021, with structured instruments administered to conveniently sampled members of the public via one-on-one interviews to collect data. These instruments included a previously designed medication literacy assessment instrument and the Newest Vital Sign United Kingdom version (NVS-UK) health literacy assessment questionnaire. Data obtained was reported using descriptive and inferential statistics. Results: Three hundred respondents were interviewed, majority of whom were females (51 %) and aged between 15 – 25 (76.6 %). The percentage of correct responses to the NVS-UK questions ranged from 22 to 58.3 %, while the total number of NVS-UK questions answered correctly by respondents ranged from 0 to 6 with a mean of 2.2 ± 1.7. Respondents’ NVS-UK scores were associated with their highest level of education completed (p = 0.001). The NVS-UK showed adequate internal consistency (Cronbach’s Alpha = 0.7) and validation of the developed medication literacy instrument against the NVS-UK demonstrated a Spearman’s rho correlation coefficient of 0.42. Conclusion: The designed instrument is valid and can be used to assess medication literacy within the country

Socio-economic Factors Influencing Extension Workers’ Effective use of Knowledge Management in Agricultural Extension Services

The study assessed the factors influencing extension workers effective use of Knowledge Management (KM) inSokoto State, Nigeria. Purposive sampling procedure was used to sample respondents from the study area andExtension Workers were selected from Sokoto Agricultural Development Project (SADP). Socio-economiccharacteristics were using structured questionnaire and a total of 188 respondents were sampled and data collectedanalysed using descriptive statistics and logit model as tools of analysis. The result of the study showed that 74.4% ofthe extension workers were male and majority (79.8%) were married. More so, 35% of the extension workers arewithin the age range of 31 – 40 years with household average size of 5-10 children. Majority (79%) of the extensionworkers had tertiary education. (35%) had experience ranging from 21-25 years on extension service delivery. About41% of respondents used motor cycle as a mean of transportation. Result of logit model shows that marital status,level of education, service experience, cosmopolitness and means of transportation had positive and significantrelationship with effectiveness of KM whereas household size and rank of extension workers had significant andnegative relationship with KM. It is therefore recommended that KM be encouraged and disseminated through topmanagement approach in SADP. This will avail quality and better extension service delivery by extension agencybecause the vast knowledge and experience garnered on effective extension service delivery by top managementofficer will be shared and passed on to junior officers. This will go in line with strengthening and improving thecapacity building of extension workers

KNOWLEDGE, ATTITUDE AND PRACTICE OF PHARMACOVIGILANCE AMONG OPERATORS OF PHARMACIES AND PATENT MEDICINE STORES IN SOKOTO METROPOLIS, NIGERIA

Background: The weak pharmacovigilance (PV) systems in many developing countries of the world have undoubtedly hampered the global quest for safe drug use. Operators of pharmacies and patent medicine stores have important roles to play in developing the PV systems in these countries being the main source of medicines for acute conditions. This study aimed to assess the knowledge, attitude and practice of pharmacovigilance among operators of pharmacies and patent medicine stores in Sokoto metropolis, Nigeria. Materials and Methods: A cross-sectional study was conducted among 249 operators of pharmacies and patent medicine stores selected by multistage sampling technique. Data were collected with a set of pretested self- administered, semi-structured questionnaire. Results: Although, the majority, 173 (69.5%) of the 249 respondents were aware of PV, less than a fifth (17.3%) had good knowledge of it. Despite positive attitude towards PV, only about half, 56 (52.3%) of the 107 respondents that had observed adverse drug reactions (ADRs) in clients reported; and of these, only about a tenth (12.8%) formally reported to the organization in charge of PV. The most commonly cited reasons for non-reporting were that they didn’t know where and how to report (51.0%), and unavailability of reporting forms (23.5%). Conclusion: This study showed poor knowledge of PV and sub-optimal ADRs reporting despite positive attitude towards it by operators of pharmacies and patent medicine stores in Sokoto metropolis, Nigeria. Sensitization of the populace and training of healthcare providers on PV and ADRs reporting are necessary for revitalizing the PV system in Sokoto State, Nigeria. Keywords: Pharmacovigilance, knowledge, attitude, practic

Countries experiences: review of district health management in developing and low developing countries

A strong healthcare system is characterized by efficient health service delivery, adequate manpower and resource generation, a sustainable financing system and good governance. District healthcare system is the one closest to the people and its performance in relation to resource allocation impacts directly on the community health status. Over the years, many of the developed nations have learned to prioritize it mainly because it remains the most ideal way of improving population health through activities of general health promotion, disease prevention and provision of basic medical care. In the developing countries, achievement of district health system is not uniform and even among countries with comparable income per capita, wide variations exist. While some have attained a commendable population health status by strengthening their district healthcare systems by redoubling government’s commitment, enhancing resource production, encouraging fairness in healthcare financing and adopting development-oriented health policies, many others are facing healthcare challenges from lack of political will, limited resource allocation and shortage of both manpower and service infrastructure. For these countries, there is an urgent need to transform the district health system so that new and existing health problems can be dealt with decisively and more efficiently. This will require a renewed commitment from the state governments, reprioritizing and readjustment of present health programs, an inter-sectorial collaboration that involves all relevant stakeholders including the communities, and a renewed investment in sustainable health policies that deliver maximum impact at minimal cost

Audit of Referral Pattern of Cancer Cases to the Radiotherapy and Oncology Unit of a Tertiary Hospital in Nigeria

Objectives: This study assessed the types of cancer cases referred to Radiotherapy and oncology unit of Ahmadu Bello University Teaching Hospital (ABUTH) Zaria, and determine the age, sex, and geopolitical zones distributions of cancer cases in ABUTH, Zaria.Methods: A retrospective study was conducted reviewing all cancer cases referred to the centre, for a period of 10 years (2004 – 2013). Ethical approval was obtained from the ethical committee of the hospital. Data capture sheet was used to collect information from the patient’s folder and this was analysed using statistical package for social sciences version 20.0Results: Three thousand nine hundred and thirty four (3934) patient’s records were reviewed. Patient’s age ranged from 0 -110 years, with a mean age of 42.4 years. Patients within the age range of 31 to 60 years had the highest cancer incidence. A total of 37 types of cancer were diagnosed with cervical cancer having the highest incidence of 1083 (27.5%). This was followed by head and neck 821 (20.9%). Intestinal cancer had the least incidence of 1 (0.02%). Female cancer cases predominated with a female to male ratio of 1.8:1. North-western Nigeria had the highest cancer incidence of 1656 (42.1%). Conclusion: This study found high incidence of cancer cases among adults age ranged 31 to 60 years with female to male ratio of 1.8:1. Cervical cancer had the highest incidence among the 37 cancer spectrum treated at the centre. The North-western Nigeria had the highest incidence of cancer cases