1,255 research outputs found

    Like a Dog of Many-Colored Glass: A Study of Shelley\u27s Use of Color

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    The purpose of this study will be to find out as much as possible about Shelley\u27s use in poetry of color and consequently, light. Since there are few previous studies of this problem to be drawn upon, this project will not be narrowed down to a specific phase of the subject, but will cover as many aspects of Shelley\u27s use of color as possible

    Refurbishment and testing of the integrated waste management system Final report, Dec. 1968 - Aug. 1969

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    Refurbishment and testing of integrated waste management system for manned space fligh

    The Zirconium Deodorant Granuloma: An Allergic Disorder

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    Detailed transonic flow field measurements about a supercritical airfoil section

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    The transonic flow field about a Whitcomb-type supercritical airfoil profile was measured in detail. In addition to the usual surface pressure distributions and wake surveys, schlieren photographs were taken and velocity vector profiles were determined in the upper surface boundary layer and in the near wake. Spanwise variations in the measured pressures were also determined. The data are analyzed with the aid of an inviscid transonic finite-difference computer program as well as with boundary layer modeling and calculation schemes

    Optimizing Wildlife Monitoirng Strategies in a Dynamic Setting (Poster)

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    Long term, broadly distributed datasets are ideal for effective wildlife management.  However, collecting and utilizing these data present a variety of challenges to management agencies.  Idaho Department of Fish and Game is currently trying to optimize their use of monitoring resources for mule deer (Odocoileus hemionus) throughout Idaho.  Three areas are being investigated for their potential to accomplish this goal: cost effectiveness, data utilization, and efficiency in data collection.  An analysis of the cost effectiveness of monitoring methods is currently being conducted.  This analysis varies the amount of each type of data available to the population model used to estimate abundance.  The precision, credible interval width (CRI), associated with the estimate is used as the measure of effectiveness, mean 95% CRIs range from 9278 - 9804.  This measure of precision is then combined with the cost of the collection technique to compare the cost effectiveness of different monitoring methods.  Further research will focus on a weighting scheme that weights data types by both sampling precision and reliability.  Thereby allowing managers to fully utilize all available data sources based on relative quality within the framework of the population model.  A third line of research focuses on increasing the efficiency of monitoring effort through an alternative sampling design derived from seasonal nutrition.  The previous lines of research will then be combined to solve a dynamic programming problem to determine the optimal methods for monitoring population abundance while accounting for changes in the availability of monitoring resources over space and time

    A comparison of SQUID imaging techniques for small defects in nonmagnetic tubes

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    Although superconducting quantum interference devices (SQUIDs) provide an exquisitively sensitive means for measuring magnetic fields, their usage in the past has been limited chiefly to biomagnetic research. However, over the past few years interest in applying SQUID techniques to the field of nondestructive evaluation (NDE) has blossomed [1]. Many experiments have exploited the sensitivity of SQUIDs for diverse NDE applications, especially those requiring large separation distances between the sensor and the item to be inspected. Our work instead has focused on the potential to detect very small defects with SQUIDs, specifically in thin-walled tubes. In this paper, we discuss three different methods for creating magnetic fields in tubes. The methods comprise (a) directly injecting a current through the tube, (b) using a separate induction coil to create induced currents in the tube, and (c) utilizing a ferromagnetic tracer technique. To illustrate the capabilities of each method, we present two-dimensional maps of the spatial distribution of the magnetic field as measured by a SQUID magnetometer — that is, SQUID images. The images will also be used to compare the sensing methods with respect to such practical considerations as relative sensitivity and signal-to-noise ratio

    A highly prevalent equine glycogen storage disease is explained by constitutive activation of a mutant glycogen synthase

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    Background: Equine type 1 polysaccharide storage myopathy (PSSM1) is associated with a missense mutation (R309H) in the glycogen synthase (GYS1) gene, enhanced glycogen synthase (GS) activity and excessive glycogen and amylopectate inclusions in muscle. Methods: Equine muscle biochemical and recombinant enzyme kinetic assays in vitro and homology modelling in silico, were used to investigate the hypothesis that higher GS activity in affected horse muscle is caused by higher GS expression, dysregulation, or constitutive activation via a conformational change. Results: PSSM1-affected horse muscle had significantly higher glycogen content than control horse muscle despite no difference in GS expression. GS activity was significantly higher in muscle from homozygous mutants than from heterozygote and control horses, in the absence and presence of the allosteric regulator, glucose 6 phosphate (G6P). Muscle from homozygous mutant horses also had significantly increased GS phosphorylation at sites 2 + 2a and significantly higher AMPKα1 (an upstream kinase) expression than controls, likely reflecting a physiological attempt to reduce GS enzyme activity. Recombinant mutant GS was highly active with a considerably lower Km for UDP-glucose, in the presence and absence of G6P, when compared to wild type GS, and despite its phosphorylation. Conclusions: Elevated activity of the mutant enzyme is associated with ineffective regulation via phosphorylation rendering it constitutively active. Modelling suggested that the mutation disrupts a salt bridge that normally stabilises the basal state, shifting the equilibrium to the enzyme's active state. General significance: This study explains the gain of function pathogenesis in this highly prevalent polyglucosan myopathy

    The importance of mother’s care for improving exclusive breastfeeding practices

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    ABSTRAKLatar Belakang: Secara global, prevalensi ibu yang memberikan ASI (air susu ibu) secara eksklusif untuk bayinya sampai dengan usia 6 bulan masih rendah (38%). Di Indonesia, pemberian ASI sudah dipraktikkan secara luas, namun yang memberikan hingga 6 bulan hanya 15,3% dan belum meningkat, meskipun Panduan Pemberian Makan Bayi dan Anak dari WHO telah tersedia.Tujuan: Studi ini bertujuan untuk menginvestigasi pentingnya pengasuhan oleh ibu (yaitu ibu memiliki peran terbesar dan menghabiskan waktu terbanyak untuk merawat bayinya sehari-hari) untuk meningkatkan praktik ASI Eksklusif pada populasi dengan tingkat ekonomi rendah.Metode: Studi cross-sectional ini dilakukan pada 408 anak usia 6 - 24 bulan dan pengasuhnya di daerah pedesaan Indonesia. Data riwayat ASI, pengasuhan anak, dan status sosio-ekonomi diambil dengan instrumen kuesioner terstruktur oleh pewawancara yang terlatih.Hasil: Lebih dari setengah (61%) Ibu di populasi ini memberikan ASI secara eksklusif pada bayinya sampai dengan usia 6 bulan. Hasil menunjukkan bahwa bayi mempunyai kesempatan yang lebih besar untuk diberikan ASI eksklusif jika diasuh oleh ibu kandungnya (OR = 4.6., 95% CI = 1.75 - 12.2) dan berasal dari keluarga dengan penghasilan rendah (OR = 1.9 95% CI = 1.08 - 3.2), setelah mengendalikan variabel lain.Kesimpulan: Pada populasi berpenghasilan rendah dimana praktik pemberian ASI telah dilakukan, tetapi pengasuhan anak dilakukan oleh seseorang selain ibu kandung, pentingnya pemberian ASI eksklusif harus terus ditekankan. Edukasi untuk meningkatkan motivasi ibu dan anggota keluarga lainnya dalam memberikan ASI, serta membangun lingkungan kerja yang ramah menyusui adalah hal yang penting untuk dilakukan.KATA KUNCI: ASI eksklusif; pengasuh; ibu kandung; tingkat ekonomi; Indonesia Timur ABSTRACTBackground: Globally, the prevalence of women who exclusively breastfeed their infants to 6 months of age remains low (38%). In Indonesia, breastfeeding is widely practiced but the prevalence of exclusive breastfeeding at 6 months is only 15,3% and has not increased over time, despite WHO IYCF guidelines.Objectives: This study aims to examine the importance of mother’s care for improving exclusive breastfeeding practices in low-income populations in Indonesia.Methods: This cross-sectional study was conducted using 408 children aged 6 - 24 months and their caregivers in rural Indonesia. five districts. Data on breastfeeding history, childcare, and socioeconomic status of families were collected using structured questionnaires by trained interviewers.Results: Over half (61%) of mothers in this population exclusively breastfed their infant at 6 months (?) Results showed that infants are more likely to receive exclusive breastfeeding if they were cared by biological mothers (OR = 4.6., 95% CI = 1.75 - 12.2) and reside in low-income households (OR = 1.9 95% CI = 1.08 - 3.2), after adjusting for confounding variables.Conclusion: In low-income populations where breastfeeding is common but the provision of child care is provided by someone besides the biological mother, the importance of exclusive breastfeeding should continue to be emphasizedKEYWORDS: exclusive breastfeeding; caregivers; biological mothers; economic level; Eastern Indonesi

    Models of Individual Blue Stragglers

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    This chapter describes the current state of models of individual blue stragglers. Stellar collisions, binary mergers (or coalescence), and partial or ongoing mass transfer have all been studied in some detail. The products of stellar collisions retain memory of their parent stars and are not fully mixed. Very high initial rotation rates must be reduced by an unknown process to allow the stars to collapse to the main sequence. The more massive collision products have shorter lifetimes than normal stars of the same mass, while products between low mass stars are long-lived and look very much like normal stars of their mass. Mass transfer can result in a merger, or can produce another binary system with a blue straggler and the remnant of the original primary. The products of binary mass transfer cover a larger portion of the colour-magnitude diagram than collision products for two reasons: there are more possible configurations which produce blue stragglers, and there are differing contributions to the blended light of the system. The effects of rotation may be substantial in both collision and merger products, and could result in significant mixing unless angular momentum is lost shortly after the formation event. Surface abundances may provide ways to distinguish between the formation mechanisms, but care must be taking to model the various mixing mechanisms properly before drawing strong conclusions. Avenues for future work are outlined.Comment: Chapter 12, in Ecology of Blue Straggler Stars, H.M.J. Boffin, G. Carraro & G. Beccari (Eds), Astrophysics and Space Science Library, Springe
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