Charge control experiments on a CH-53E helicopter in a dusty environment

Charge control tests were carried out on a ground based, Marine Corps helicopter to determine if control of the electric fields acting on the engine exhaust gases could be used to reduce the electrification of the helicopter when it operated in a dusty atmosphere. The test aircraft was flown to a dusty, unpaved area and was then isolated electrically from the earth. When the helicopter engines were operated at ground idle with the rotor locked, the isolated aircraft charged positively, as had been observed previously. However, when the rotor brake was released and the turning rotor created a downdraft that raised dust clouds, the aircraft always became charged more positively, to potentials ranging form +30 to +45 kV. The dust clouds raised by the rotor downwash invariably carried negative space charges with concentrations of up to -100 nC/cu m and caused surface electric fields with strengths of up to 10 kV/m immediately down wind of the aircraft. The natural charging of the helicopter operating in these dust clouds was successfully opposed by control of the electric fields acting on the hot, electrically conductive exhaust gases. The control was achieved by placing electrostatic shield around the exhausts

Aircraft measurements of electrified clouds at Kennedy Space Center. Part 2: Case study: 4 November 1988 (88309)

During the fall of 1988, a Schweizer airplane equipped to measure electric field and other meteorological parameters flew over Kennedy Space Center (KSC) in a program to study clouds defined in the existing launch restriction criteria. A case study is presented of a single flight over KSC on November 4, 1988. This flight was chosen for two reasons: (1) the clouds were weakly electrified, and no lightning was reported during the flight; and (2) electric field mills in the surface array at KSC indicated field strengths greater than 3 kV/m, yet the aircraft flying directly over them at an altitude of 3.4 km above sea level measured field strengths of less than 1.6 kV/m. A weather summary, sounding description, record of cloud types, and an account of electric field measurements are included

Aircraft measurements of electrified clouds at Kennedy Space Center

The space-vehicle launch commit criteria for weather and atmospheric electrical conditions in us at Cape Canaveral Air Force Station and Kennedy Space Center (KSC) have been made restrictive because of the past difficulties that have arisen when space vehicles have triggered lightning discharge after their launch during cloudy weather. With the present ground-base instrumentation and our limited knowledge of cloud electrification process over this region of Florida, it has not been possible to provide a quantitative index of safe launching conditions. During the fall of 1988, a Schweizer 845 airplane equipped to measure electric field and other meteorological parameters flew over KSC in a program to study clouds defined in the existing launch restriction criteria. All aspects of this program are addressed including planning, method, and results. A case study on the November 4, 1988 flight is also presented

Aircraft measurements of electrified clouds at Kennedy Space Center, part 3

Flights made by the Special Purpose Test Vehicle for Atmospheric Research (SPTVAR) airplane during a second deployment to Florida during the summer of 1989 are discussed. The findings based on the data gathered are presented. The progress made during the second year of the project is discussed. The summer 1989 study was carried out with the support and guidance of Col. John Madura, Commander of Detachment 11, 2nd Weather Squadron, USAF, at Patrick Air Force Base (PAFB) and Cape Canaveral Air Force Station. The project goals were to develop and demonstrate techniques for measuring the electric field aloft and locating regions of charge during flight within and near clouds; to characterize the electric conditions that are presently identified as a threat to space launch vehicles; and to study the correlation between the electric field aloft and that at Kennedy Space Center's ground-based electric field mill array for a variety of electrified clouds

Aircraft measurements of electrified clouds at Kennedy Space Center. Part 1: 1988 flights

During the fall of 1988, a Schweizer 845 airplane equipped to measure electric field and other meteorological parameters flew over Kennedy Space Center in a program to study clouds defined in the existing launch retriction requirements. The special purpose test vehicle for atmospheric research (SPTVAR) was suitable for flights through thunderclouds and was instrumented to measure all three components of the ambient electric vector. The main goals of the project were: (1) to develop and demonstrate techniques for measuring the electric field aloft and locate regions of charge during flight; (2) to characterize the electrical conditions within and near clouds that are presently identified as a threat to space launch vehicles; and (3) to study the correlation between the electric field aloft and that at Kennedy Space Center's ground-based field mill network for a variety of electrified clouds

CD45 Isoform Expression in Microglia and Inflammatory Cells in HIV-1 Encephalitis

CD45 is a membrane tyrosine phosphatase that modulates the function of the hematopoietic cells. In vitro, agonist antibodies to CD45RO or CD45RB isoforms have been shown to suppress microglial activation, but whether microglia in vivo express these isoforms in HIV encephalitis (HIVE) is unknown. Brain sections from control and HIVE were immunostained for CD45 isoforms using exon-specific antibodies (RA, RB, RC and RO). RA and RC were limited to rare lymphocytes, while RB expression was robust in microglia and inflammatory cells. RO was low in control microglia, but increased in HIVE. RO was also localized to macrophages and CD8+ T cells. Targeting CD45 in vivo with isoform-specific antibodies remains a therapeutic option for neuroinflammatory diseases

Compton Scattering Cross Section on the Proton at High Momentum Transfer

Cross-section values for Compton scattering on the proton were measured at 25 kinematic settings over the range s = 5-11 and -t = 2-7 GeV2 with statistical accuracy of a few percent. The scaling power for the s-dependence of the cross section at fixed center of mass angle was found to be 8.0 +/ 0.2, strongly inconsistent with the prediction of perturbative QCD. The observed cross-section values are in fair agreement with the calculations using the handbag mechanism, in which the external photons couple to a single quark.Comment: 5 pages, 5 figure

Angiotensin receptors in GtoPdb v.2023.1

The actions of angiotensin II (Ang II) are mediated by AT1 and AT2 receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Angiotensin receptors [63, 155]), which have around 30% sequence similarity. The decapeptide angiotensin I, the octapeptide angiotensin II and the heptapeptide angiotensin III are endogenous ligands. losartan, candesartan, olmesartan, telmisartan, etc. are clinically used AT1 receptor blockers

Angiotensin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

The actions of angiotensin II (Ang II) are mediated by AT1 and AT2 receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Angiotensin receptors [61, 152]), which have around 30% sequence similarity. The decapeptide angiotensin I, the octapeptide angiotensin II and the heptapeptide angiotensin III are endogenous ligands. losartan, candesartan, telmisartan, etc. are clinically used AT1 receptor blockers