4,465 research outputs found
Changing Gear: Delivering the Social Dividend
In December 2001, the Institute of Policy Studies and Business New Zealand co-hosted a one day symposium entitled ‘Changing Gear: Delivering the Social Dividend’. It was addressed and attended by members of academia, the public sector and the business sector. This IPS Policy Paper brings together a number of the presentations to that symposium. It includes papers delivered by Arthur Grimes, Colin Campbell-Hunt and
Ross Wilson, plus a summary of key points raised in the address by Glenn Withers, and some concluding remarks by Rod Oram
The Importance of Taking a Military History
The most important action a provider can take to ensure that a veteran receives optimal health care is perhaps the easiest and, ironically, the most neglected: asking if a patient has served in the military and taking a basic military history. In previously published articles, Jeffrey Brown1 and Ross Boyce,2 physicians with prior military service, reported that their own health care providers had rarely asked about their service. For Dr Brown, in the four decades since his combat service in Vietnam, he noted
Low Frequency Vibration Approach for Assessing Performance of Wood Floor Systems1
The primary means of inspecting buildings and other structures is to evaluate each structure member individually. This is a time-consuming and expensive process, particularly if sheathing or other covering materials must be removed to access the structural members. The objective of this study was to determine if a low frequency vibration method could be used to effectively assess the structural performance of wood floors as component systems. Twelve wood floors were constructed with solid sawn wood joists in the laboratory and tested with both vibration and static load methods. The results indicated that the forced vibration method was capable of measuring the fundamental natural frequency (bending mode) of the wood floors investigated. An analytical model derived from the flexural beam theory was found to fit the physics of the floor structures and can be used to correlate natural frequency to section modulus (EI product) of the floor systems
A parametric evaluation of the interplay between geometry and scale on cross-flow turbine performance
Cross-flow turbines harness kinetic energy in wind or moving water. Due to
their unsteady fluid dynamics, it can be difficult to predict the interplay
between aspects of rotor geometry and turbine performance. This study considers
the effects of three geometric parameters: the number of blades, the preset
pitch angle, and the chord-to-radius ratio. The relevant fluid dynamics of
cross-flow turbines are reviewed, as are prior experimental studies that have
investigated these parameters in a more limited manner. Here, 223 unique
experiments are conducted across an order of magnitude of diameter-based
Reynolds numbers () in which the
performance implications of these three geometric parameters are evaluated. In
agreement with prior work, maximum performance is generally observed to
increase with Reynolds number and decrease with blade count. The broader
experimental space identifies new parametric interdependencies; for example,
the optimal preset pitch angle is increasingly negative as the chord-to-radius
ratio increases. Because these experiments vary both the chord-to-radius ratio
and blade count, the performance of different rotor geometries with the same
solidity (the ratio of total blade chord to rotor circumference) can also be
evaluated. Results demonstrate that while solidity can be a poor predictor of
maximum performance, across all scales and tested geometries it is an excellent
predictor of the tip-speed ratio corresponding to maximum performance. Overall,
these results present a uniquely holistic view of relevant geometric
considerations for cross-flow turbine rotor design and provide a rich dataset
for validation of numerical simulations and reduced-order models.Comment: SUBMITTED to Renewable and Sustainable Energy Review
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\u3cem\u3ePseudomonas aeruginosa\u3c/em\u3e reverse diauxie is a multidimensionl, optimized, resource utilization strategy
Pseudomonas aeruginosa is a globally-distributed bacterium often found in medical infections. The opportunistic pathogen uses a different, carbon catabolite repression (CCR) strategy than many, model microorganisms. It does not utilize a classic diauxie phenotype, nor does it follow common systems biology assumptions including preferential consumption of glucose with an ‘overflow’ metabolism. Despite these contradictions, P. aeruginosa is competitive in many, disparate environments underscoring knowledge gaps in microbial ecology and systems biology. Physiological, omics, and in silico analyses were used to quantify the P. aeruginosa CCR strategy known as ‘reverse diauxie’. An ecological basis of reverse diauxie was identified using a genome-scale, metabolic model interrogated with in vitro omics data. Reverse diauxie preference for lower energy, nonfermentable carbon sources, such as acetate or succinate over glucose, was predicted using a multidimensional strategy which minimized resource investment into central metabolism while completely oxidizing substrates. Application of a common, in silico optimization criterion, which maximizes growth rate, did not predict the reverse diauxie phenotypes. This study quantifies P. aeruginosa metabolic strategies foundational to its wide distribution and virulence including its potentially, mutualistic interactions with microorganisms found commonly in the environment and in medical infections
Genomic correlates of recombination rate and its variability across eight recombination maps in the western honey bee (Apis mellifera L.)
Background: Meiotic recombination has traditionally been explained based on the structural requirement to stabilize homologous chromosome pairs to ensure their proper meiotic segregation. Competing hypotheses seek to explain the emerging findings of significant heterogeneity in recombination rates within and between genomes, but intraspecific comparisons of genome-wide recombination patterns are rare. The honey bee (Apis mellifera) exhibits the highest rate of genomic recombination among multicellular animals with about five cross-over events per chromatid. Results: Here, we present a comparative analysis of recombination rates across eight genetic linkage maps of the honey bee genome to investigate which genomic sequence features are correlated with recombination rate and with its variation across the eight data sets, ranging in average marker spacing ranging from 1 Mbp to 120 kbp. Overall, we found that GC content explained best the variation in local recombination rate along chromosomes at the analyzed 100 kbp scale. In contrast, variation among the different maps was correlated to the abundance of microsatellites and several specific tri- and tetra-nucleotides. Conclusions: The combined evidence from eight medium-scale recombination maps of the honey bee genome suggests that recombination rate variation in this highly recombining genome might be due to the DNA configuration instead of distinct sequence motifs. However, more fine-scale analyses are needed. The empirical basis of eight differing genetic maps allowed for robust conclusions about the correlates of the local recombination rates and enabled the study of the relation between DNA features and variability in local recombination rates, which is particularly relevant in the honey bee genome with its exceptionally high recombination rate. © 2014 Ross et al
Exploring multi-objective trade-offs in the design space of a waste heat recovery system
A waste heat recovery system (WHRS) is used to capture waste heat released from an industrial process, and transform the heat into reusable energy. In practice, it can be difficult to identify the optimal form of a WHRS for a particular installation, since this can depend on various design objectives, which are often mutually exclusive. More so when the number of objectives is large. To address this problem, a multi-objective evolutionary algorithm (MOEA) was used to explore and characterise the trade-off surface within the design space of a particular WHRS. A combination of clustering algorithm and parallel coordinates plots was proposed for use in analysing the results. The trade-off surface is first segmented using a clusteringalgorithm and parallel coordinates plots are then used to both visualise and understand the resulting set of Pareto-optimal designs. As a case study, a simulation of a WHRS commonly found in the foodand drinks process industries was developed, comprising of a desuperheater coupled to a hot water reservoir. The system was parameterised, considering typical objectives, and the MOEA used to build a library of alternative Pareto-optimal designs that can be used by installers. The resulting visualisation are used to better understand the sensitivity of the system’s parameters and their trade-offs, providing another source of information for prospective installations
Modelling Canopy Flows over Complex Terrain
Recent studies of flow over forested hills have been motivated by a number of important applications including understanding CO22 and other gaseous fluxes over forests in complex terrain, predicting wind damage to trees, and modelling wind energy potential at forested sites. Current modelling studies have focussed almost exclusively on highly idealized, and usually fully forested, hills. Here, we present model results for a site on the Isle of Arran, Scotland with complex terrain and heterogeneous forest canopy. The model uses an explicit representation of the canopy and a 1.5-order turbulence closure for flow within and above the canopy. The validity of the closure scheme is assessed using turbulence data from a field experiment before comparing predictions of the full model with field observations. For near-neutral stability, the results compare well with the observations, showing that such a relatively simple canopy model can accurately reproduce the flow patterns observed over complex terrain and realistic, variable forest cover, while at the same time remaining computationally feasible for real case studies. The model allows closer examination of the flow separation observed over complex forested terrain. Comparisons with model simulations using a roughness length parametrization show significant differences, particularly with respect to flow separation, highlighting the need to explicitly model the forest canopy if detailed predictions of near-surface flow around forests are required
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