1,034 research outputs found

    Using interactive screen experiments as pre-laboratory tasks to enhance student learning

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    The teaching of first year undergraduate practical physics is currently faced with a difficult problem: the disparity in the level of practical physics many university entrant students have encountered prior to their arrival. Those with little practical physics experience enter the laboratory for the first time with a great deal of anxiety, which represents a barrier to their learning. This anxiety is magnified when their fellow students, some of whom have significant practical laboratory experience in their recent educational background, deal easily with the same situation. At Durham University, Interactive Screen Experiments (ISEs) have been used to familiarise students with laboratory equipment as part of an assessed pre-laboratory task for the first year physics laboratory, after which they perform real experiments

    The hyperfine Paschen-Back Faraday effect

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    We investigate experimentally and theoretically the Faraday effect in an atomic medium in the hyperfine Paschen–Back regime, where the Zeeman interaction is larger than the hyperfine splitting. We use a small permanent magnet and a micro-fabricated vapour cell, giving magnetic fields of the order of a tesla. We show that for low absorption and small rotation angles, the refractive index is well approximated by the Faraday rotation signal, giving a simple way to measure the atomic refractive index. Fitting to the atomic spectra, we achieve magnetic field sensitivity at the 10−4 level. Finally we note that the Faraday signal shows zero crossings which can be used as temperature insensitive error signals for laser frequency stabilization at large detuning. The theoretical sensitivity for 87Rb is found to be ~40 kHz °C−1

    Laser spectroscopy of hot atomic vapours: from ’scope to theoretical fit

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    The spectroscopy of hot atomic vapours is a hot topic. Many of the work-horse techniques of contemporary atomic physics were first demonstrated in hot vapours. Alkali-metal atomic vapours are ideal media for quantum-optics experiments as they combine: a large resonant optical depth; long coherence times; and well-understood atom–atom interactions. These features aid with the simplicity of both the experimental set up and the theoretical framework. The topic attracts much attention as these systems are ideal for studying both fundamental physics and has numerous applications, especially in sensing electromagnetic fields and quantum technology. This tutorial reviews the necessary theory to understand the Doppler broadened absorption spectroscopy of alkali-metal atoms, and explains the data taking and processing necessary to compare theory and experiment. The aim is to provide a gentle introduction to novice scientists starting their studies of the spectroscopy of thermal vapours while also calling attention to the application of these ideas in the contemporary literature. In addition, the work of expert practitioners in the field is highlighted, explaining the relevance of three extensively-used software packages that complement the presentation herein

    Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: Marker candidates for dementia with Lewy bodies

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    Background: The measurement of biomarkers in cerebrospinal fluid (CSF) has gained increasing acceptance in establishing the diagnosis of some neurodegenerative diseases. Heart-type fatty acid-binding protein (H-FABP) was recently discovered in CSF and serum of patients with neurodegenerative diseases. Objective: We investigated H-FABP in CSF and serum alone and in combination with CSF tau protein to evaluate these as potential biomarkers for the differentiation between dementia with Lewy bodies (DLB) and Alzheimer's disease (AD). Methods: We established H-FABP and tau protein values in a set of 144 persons with DLB (n = 33), Parkinson disease with dementia (PDD; n = 25), AD (n = 35) and nonclemented neurological controls (NNC; n = 51). Additionally, serum H-FABP levels were analyzed in idiopathic Parkinson disease patients without evidence of cognitive decline (n = 45) using commercially available enzyme-linked immunosorbent assays. We calculated absolute values of HFABP and tau protein in CSF and serum and established relative ratios between the two to obtain the best possible match for the clinical working diagnosis. Results: Serum HFABP levels were elevated in DLB and PDD patients compared with NNC and AD subjects. To better discriminate between DLB and AD, we calculated the ratio of serum H-FABP to CSF tau protein levels. At the arbitrary chosen cutoff ratio >= 8 this quotient reached a sensitivity of 91% and a specificity of 66%. Conclusion: Our results suggest that the measurement of CSF tau protein, together with H-FABP quantification in serum and CSF, and the ratio of serum H-FABP to CSF tau protein represent marker candidates for the differentiation between AD and DLB. Copyright (c) 2007 S. Karger AG, Basel

    The return of the bursts: Thermonuclear flashes from Circinus X-1

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    We report the detection of 15 X-ray bursts with RXTE and Swift observations of the peculiar X-ray binary Circinus X-1 during its May 2010 X-ray re-brightening. These are the first X-ray bursts observed from the source after the initial discovery by Tennant and collaborators, twenty-five years ago. By studying their spectral evolution, we firmly identify nine of the bursts as type I (thermonuclear) X-ray bursts. We obtain an arcsecond location of the bursts that confirms once and for all the identification of Cir X-1 as a type I X-ray burst source, and therefore as a low magnetic field accreting neutron star. The first five bursts observed by RXTE are weak and show approximately symmetric light curves, without detectable signs of cooling along the burst decay. We discuss their possible nature. Finally, we explore a scenario to explain why Cir X-1 shows thermonuclear bursts now but not in the past, when it was extensively observed and accreting at a similar rate.Comment: Accepted for publication in The Astrophysical Journal Letters. Tables 1 & 2 merged. Minor changes after referee's comments. 5 pages, 4 Figure

    Investigation of high-pressure planetary ices by cryo-recovery. II. High-pressure apparatus, examples and a new high-pressure phase of MgSO₄·5H₂O

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    An apparatus is described for the compression of samples to ∼2 GPa at temperatures from 80 to 300 K, rapid chilling to 80 K whilst under load and subsequent recovery into liquid nitro­gen after the load is released. In this way, a variety of quenchable high-pressure phases of many materials may be preserved for examination outside the high-pressure sample environment, with the principal benefit being the ability to obtain high-resolution powder diffraction data for phase identification and structure solution. The use of this apparatus, in combination with a newly developed cold-loadable low-temperature stage for X-ray powder diffraction (the PheniX-FL), is illustrated using ice VI (a high-pressure polymorph of ordinary water ice that is thermodynamically stable only above ∼0.6 GPa) as an example. A second example using synthetic epsomite (MgSO₄·7H₂O) reveals that, at ∼1.6 GPa and 293 K, it undergoes incongruent melting to form MgSO₄·5H₂O plus brine, contributing to a long-standing debate on the nature of the high-pressure behaviour of this and similar highly hydrated materials. The crystal structure of this new high-pressure polymorph of MgSO₄·5H₂O has been determined at 85 K in space group Pna2₁ from the X-ray powder diffraction pattern of a sample recovered into liquid nitro­gen and is found to differ from that of the known ambient-pressure phase of MgSO₄·5H₂O (pentahydrite, space group [P {\overline 1}]), consisting of corner-sharing MgO₆—SO₄ ion pairs rather than infinite corner-sharing chains

    Marketing Renewable Energy in the United Kingdom

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    This chapter focuses on the renewable energy market in the UK. First we discuss the impact of privatization, then show what preconditions might be important. The main conclusion drawn from the analysis is that in the UK, as well as in other countries, new policy frameworks need to guide the transition from an energy system designed to achieve short-term efficiencies through market operation to a long-term approach that would embrace new uncertainties. Both market interests and environmental protection need to be secured in order to guarantee the levels of investment needed in the UK’s renewable energy market

    The role of healthcare professionals in encouraging parents to see and hold their stillborn baby: a meta-synthesis of qualitative studies.

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    Background: Globally, during 2013 there were three million recorded stillbirths. Where clinical guidelines exist some recommend that professionals do not encourage parental contact. The guidance is based on quantitative evidence that seeing and holding the baby is not beneficial for everyone, but has been challenged by bereaved parents' organisations. We aim to inform future guideline development through a synthesis of qualitative studies reporting data relevant to the research question; how does the approach of healthcare professionals to seeing and holding the baby following stillbirth impact parents views and experiences? Methods/Findings: Using a predetermined search strategy of PubMed and PsychINFO we identified robust qualitative studies reporting bereaved parental views and/or experiences relating to seeing and holding their stillborn baby (final search 24 February, 2014). Eligible studies were English language, reporting parental views, with gestational loss >20weeks. Quality was independently assessed by three authors using a validated tool. We used meta-ethnographic techniques to identify key themes and a line of argument synthesis. We included 12 papers, representing the views of 333 parents (156 mothers, 150 fathers, and 27 couples) from six countries. The final themes were: "[Still]birth: Nature of care is paramount", "Real babies: Perfect beauties, monsters and spectres", and "Opportunity of a lifetime lost." Our line-of-argument synthesis highlights the contrast between all parents need to know their baby, with the time around birth being the only time memories can be made, and the variable ability that parents have to articulate their preferences at that time. Thus, we hypothesised that how health professionals approach contact between parents and their stillborn baby demands a degree of active management. An important limitation of this paper is all included studies originated from high income, westernised countries raising questions about the findings transferability to other cultural contexts. We do not offer new evidence to answer the question "Should parents see and hold their stillborn baby?", instead our findings advance understanding of how professionals can support parents to make appropriate decisions in a novel, highly charged and dynamic situation. Conclusions: Guidelines could be more specific in their recommendations regarding parental contact. The role of healthcare professionals in encouraging parents to see and hold their stillborn baby is paramount. Parental choice not to see their baby, apprehension, or uncertainty should be continuously revisited in the hours after birth as the opportunity for contact is fleeting and final

    Early-stage [123I]beta-CIT SPECT and long-term clinical follow-up in patients with an initial diagnosis of Parkinson's disease

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    beta-CIT binding in both caudate nuclei was lower than in the group of patients with IPD. In addition, putamen to caudate binding ratios were higher in the group of APS patients. In spite of these differences, individual binding values showed considerable overlap between the groups. CONCLUSION: [(123)I]beta-CIT SPECT scanning in early-stage, untreated parkinsonian patients revealed a relative sparing of the caudate nucleus in patients with IPD as compared to patients later (re)diagnosed with APS. Nevertheless, the pattern of striatal involvement appears to have little predictive value for a later re-diagnosis of APS in individual case
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