Dilemmatic Deliberations In Kierkegaard’s Fear and Trembling

My central claim in this paper is that Kierkegaard’s Fear and Trembling is governed by the basic aim to articulate a real dilemma, and to elicit its proper recognition as such. I begin by indicating how Kierkegaard’s works are shaped in general by this aim, and what the aim involves. I then show how the dilemmaticstructure of Fear and Trembling is obscured in a recent dispute between Michelle Kosch and John Lippitt regarding the basic aims and upshot of the book. Finally, I consider two critical questions: Why does Kierkegaard present his dilemmatic reasoning in the form of a “dialectical lyric”? And why does he write a book that aims only to articulate a dilemma, and not also to resolve it

Organelle aging: Lessons from model organisms

Most cellular processes descend into failure during aging. While a large collection of longevity pathways has been identified in the past decades, the mechanism for age-related decline of cellular homeostasis and organelle function remains largely unsolved. It is known that many organelles undergo structural and functional changes during normal aging, which significantly contributes to the decline of tissue function at old ages. Since recent studies have revealed an emerging role of organelles as regulatory hubs in maintaining cellular homeostasis, understanding of organelle aging will provide important insights into the cellular basis of organismal aging. Here we review current progress on the characterization of age-dependent structural and functional alterations in the more well-studied organelles, as well as the known mechanisms governing organelle aging in model organisms, with a special focus on the fruit fly Drosophila melanogaster

Clinical study of retinal detachment associated with choroidal detachment

AIM: To analyze the clinical characteristics of retinal detachment associated with choroidal detachment and to evaluate the surgical techniques, the efficacy and operation time for treatment.<p>METHODS: We reviewed and analyzed the operative effects of vitreoretinal surgeries in 45 patients(45 eyes)with retinal and choroidal detachment in our hospital from January, 2010 to January, 2012. In these 45 patients, there were 38 patients of rhegmatogenous retinal detachment associated with choroidal detachment, 7 patients of retinal redetachment associated with choroidal detachment. The surgical techniques include scleral encircling operation, epichoroidal space drainage by sclerocentesis intraocular photocoagulation, gas-fluid exchange, perfluoropropane(C₃F₈)or silicone oil intraocular tamponade and vitreoretinal surgery.<p>RESULTS: The drainage of the suprachoroidal space liquid and blood was successful in 45 eyes. Silicone oil tamponade was performed for 39 eyes and C₃F₈ tamponade for 6 eyes. Retinas and choroids were all reattached and retinal holes were closed. Visual acuities were improved, ≥0.1 in 23 eyes.<p>CONCLUSION: The vitreoretinal surgery and external drainage by sclerocentesis and scleral encircling operation is an effective operating method for rhegmatogenous retinal detachment associated with choroidal detachment

Comparative Study of TCM Syndrome Scale for Liver Disease and Chronic Liver Disease Questionnaire Based on Assessment of Posthepatitic Cirrhosis

Objective. To compare and analyze the relevance and applied value of chronic liver disease questionnaire (CLDQ) and Traditional Chinese Medicine liver disease questionnaire (TCMLDQ) in patients with posthepatitic cirrhosis. Methods. The data of 146 patients' scales of CLDQ and TCMLDQ which based on the characteristics of chinese medical symptoms were collected. We made comparative analysis of the relationship between these two scales by the linear regression model and canonical correlation method and evaluated the advantages and disadvantages of two scales about its items setting and dimension definition. Result. There is a negative correlation in total scores between the two scales and the linear regression equation: CLDQ = 239.38 − 1.232TCMLDQ. The further canonical correlation analysis was used to analyze the two extracted canonical correlative variables with significances (P < 0.05), and the results showed that the overall negative correlation between the two scales mainly came from contributions of both the four dimensions of TCMLDQ (CS, GSYX, GYPX, and OS) and the five dimensions of CLDQ (AS, FA, SS, AC, and EF). Conclusion. These two scales have good consistency in the evaluation of severity and life quality of liver cirrhosis patients, so we suggested that TCMLDQ can be used to evaluate the severity and life quality of patients with posthepatitic cirrhosis

Open Design and 3D Printing of Face Shields: The Case Study of a UK-China Initiative

At the start of the COVID-19 outbreak, many countries lacked personal protective equipment (PPE) to protect healthcare workers. To address this problem, open design and 3D printing technologies were adopted to provide much-in-need PPEs for key workers. This paper reports an initiative by designers and engineers in the UK and China. The case study approach and content analysis method were used to study the stakeholders, the design process, and other relevant issues such as regulation. Good practice and lessons were summarised, and suggestions for using distributed 3D printing to supply PPEs were made. It concludes that 3D printing has played an important role in producing PPEs when there was a shortage of supply, and distributed manufacturing has the potential to quickly respond to local small-bench production needs. In the future, clearer specification, better match of demands and supply, and quicker evaluation against relevant regulations will provide efficiency and quality assurance for 3D printed PPE supplies

Towards harmonious East-West educational partnerships: a study of cultural differences between Taiwanese and Norwegian engineering students

The collaboration activities between educational institutions in the East and the West are on the increase as an increasingly globalized economy requires graduates to have the skills to work across cultural divides. Such collaborations are difficult and require patience. One challenge is that students or teachers may have misconceptions about aspects of the other culture that may cause problems. This study sets out to identify what values students in typical Eastern and Western societies associate with a good student, good student behavior, good teachers and good lectures with the purpose to identify discrepancies. This study is based on the results of a pair-wise ranking questionnaire completed by 233 Taiwanese and Norwegian students of both engineering and non-technical subjects. The results confirm some established beliefs regarding culturally related differences. However, several issues were found to be culturally neutral, and cultural differences were identified for several issues that were predicted to be culturally neutral. The results of this study may be useful to educators involved in East–West internationalization