287 research outputs found
OL-027 Increased expression of Rho-Kinase-I, p-myosin-binding subunit Thr-697 and alpha smooth muscle actin in rats liver tissues during hepatic fibrogenesis
Effect of Preliminary Torsional Strain on Low-Cycle Fatigue of Q345B Structural Steel
Effect of preliminary torsional strain on low-cycle fatigue of Q345B steel was studied. The specimens were first 0, 180, and 360° twisted, then the low-cycle fatigue of Q345B steel was evaluated in the strain range of 0.3–0.8% by the method of axisymmetrical strain. The cycling response, cyclic stress–strain relationship, strain–life relationship, fatigue life prediction model, and seismic stability at different torsion angles were obtained and analyzed. The strain–life curve is shown to slope down as a power function. The fatigue life comes down with preliminary torsional strain at a constant level. The cycling response varied from cyclic hardening to cyclic softening in preliminary torsion, and the cyclic hardening rate increased linearly with the strain amplitude. The parameters of the Coffin–Manson relation are corroborated with experimental data. After heat treatment, the seismic stability of the material is improved, with torsional strain greatly reducing this characteristic. Electron microscope examination of fatigue fracture revealed a fatigue crack initiating on the surface of the specimen. The propagating crack deviated from its direction, and plasticity of the material dropped as a result of preliminary torsional strain.Изучено влияние деформации предварительного кручения на малоцикловую усталость стали Q345B. Вначале образцы скручивали на 0, 180 и 360°, затем методом осесимметричной деформации определяли малоцикловую усталость стали Q345B в диапазоне деформаций 0.3 0.8%. Получены и проанализированы характеристика циклических изменений, зависимость циклического изменения напряжения от деформации, зависимость деформация долговечность, модель прогнозирования усталостной долговечности и сейсмостойкость при различных углах кручения. Показано, что кривая деформация долговечность идет вниз и описывается степенной функцией. Усталостная долговечность снижается с увеличением деформации предварительного кручения при постоянном уровне последней. Характеристика циклических изменений варьировала от циклического упрочнения до циклического разупрочнения при кручении, скорость циклического упрочнения возрастала линейно с повышением амплитуды деформации. Параметры зависимости Коффина Мэнсона подтверждаются экспериментальными данными. После термообработки сейсмостойкость материала улучшается, при этом деформация предварительного кручения существенно снижает ее. Электронно-микроскопическое исследование усталостного разрушения выявило зарождение усталостной трещины на поверхности образца. Растущая трещина отклонялась от своего направления, пластичность материала снижалась в результате деформации предварительного кручения.Вивчено вплив деформації попереднього кручення на малоціклову втому стали Q345B. Спочатку зразки скручували на 0, 180 і 360 °, потім методом вісесиметричної деформації визначали малоціклову втому стали Q345B в діапазоні деформацій 0.3-0.8%. Отримано і проаналізовано характеристику циклічних змін, залежність циклічної зміни напржень від деформації, залежність деформація-довговічність, модель прогнозування втомної довговічності і сейсмостійкості при різних кутах кручення. Показано, що крива деформація - довговічність йде вниз і описується ступеневою функцією. Втомна довговічність знижується зі збільшенням деформації попереднього кручення при постійному рівні останньої. Характеристика циклічних змін варіювала від циклічного зміцнення до циклічного знеміцнення при крученні, швидкість циклічного зміцнення зростала лінійно з підвищенням амплітуди деформації. Параметри залежності Коффина-Менсона підтверджуються експериментальними даними. Після термообробки сейсмостійкість матеріалу поліпшується, при цьому деформація попереднього кручення істотно знижує її. Електронно-мікроскопічне дослідження втомного руйнування виявило зародження втомної тріщини на поверхні зразка. Зростаюча тріщина відхилялася від свого напрямку, пластичність матеріалу знижувалася в результаті деформації попереднього кручення
Cryptic photosynthesis, Extrasolar planetary oxygen without a surface biological signature
On the Earth, photosynthetic organisms are responsible for the production of
virtually all of the oxygen in the atmosphere. On the land, vegetation reflects
in the visible, leading to a red edge that developed about 450 Myr ago and has
been proposed as a biosignature for life on extrasolar planets. However, in
many regions of the Earth, and particularly where surface conditions are
extreme, for example in hot and cold deserts, photosynthetic organisms can be
driven into and under substrates where light is still sufficient for
photosynthesis. These communities exhibit no detectable surface spectral
signature to indicate life. The same is true of the assemblages of
photosynthetic organisms at more than a few metres depth in water bodies. These
communities are widespread and dominate local photosynthetic productivity. We
review known cryptic photosynthetic communities and their productivity. We link
geomicrobiology with observational astronomy by calculating the disk-averaged
spectra of cryptic habitats and identifying detectable features on an exoplanet
dominated by such a biota. The hypothetical cryptic photosynthesis worlds
discussed here are Earth-analogs that show detectable atmospheric biomarkers
like our own planet, but do not exhibit a discernable biological surface
feature in the disc-averaged spectrum.Comment: 23 pages, 2 figures, Astrobiology (TBP) - updated Table 1, typo in
detectable O2 correcte
Therapeutic effect of hydrogen sulfide-releasing L-dopa derivative ACS84 on 6-OHDA-induced Parkinson's disease rat model
Parkinson's disease (PD), characterized by loss of dopaminergic neurons in the substantia nigra, is a neurodegenerative disorder of central nervous system. The present study was designed to investigate the therapeutic effect of ACS84, a hydrogen sulfide-releasing-L-Dopa derivative compound, in a 6-hydroxydopamine (6-OHDA)-induced PD model. ACS84 protected the SH-SY5Y cells against 6-OHDA-induced cell injury and oxidative stress. The protective effect resulted from stimulation of Nrf-2 nuclear translocation and promotion of anti-oxidant enzymes expression. In the 6-OHDA-induced PD rat model, intragastric administration of ACS84 relieved the movement dysfunction of the model animals. Immunofluorescence staining and High-performance liquid chromatography analysis showed that ACS84 alleviated the loss of tyrosine-hydroxylase positive neurons in the substantia nigra and the declined dopamine concentration in the injured striatums of the 6-OHDA-induced PD model. Moreover, ACS84 reversed the elevated malondialdehyde level and the decreased glutathione level in vivo. In conclusion, ACS84 may prevent neurodegeneration via the anti-oxidative mechanism and has potential therapeutic values for Parkinson's disease
Partial wave analysis of J/\psi \to \gamma \phi \phi
Using events collected in the BESII detector, the
radiative decay is
studied. The invariant mass distribution exhibits a near-threshold
enhancement that peaks around 2.24 GeV/.
A partial wave analysis shows that the structure is dominated by a
state () with a mass of
GeV/ and a width of GeV/. The
product branching fraction is: .Comment: 11 pages, 4 figures. corrected proof for journa
Measurements of the observed cross sections for exclusive light hadrons containing at , 3.650 and 3.6648 GeV
By analyzing the data sets of 17.3, 6.5 and 1.0 pb taken,
respectively, at , 3.650 and 3.6648 GeV with the BES-II
detector at the BEPC collider, we measure the observed cross sections for
, , ,
and at the three energy
points. Based on these cross sections we set the upper limits on the observed
cross sections and the branching fractions for decay into these
final states at 90% C.L..Comment: 7 pages, 2 figure
Direct Measurements of Absolute Branching Fractions for D0 and D+ Inclusive Semimuonic Decays
By analyzing about 33 data sample collected at and around 3.773
GeV with the BES-II detector at the BEPC collider, we directly measure the
branching fractions for the neutral and charged inclusive semimuonic decays
to be and , and determine the ratio of the two branching
fractions to be
A study of charged kappa in
Based on events collected by BESII, the decay
is studied. In the invariant mass
spectrum recoiling against the charged , the charged
particle is found as a low mass enhancement. If a Breit-Wigner function of
constant width is used to parameterize the kappa, its pole locates at MeV/. Also in this channel,
the decay is observed for the first time.
Its branching ratio is .Comment: 14 pages, 4 figure
Partial Wave Analysis of
BES data on are presented. The
contribution peaks strongly near threshold. It is fitted with a
broad resonance with mass MeV, width MeV. A broad resonance peaking at 2020 MeV is also required
with width MeV. There is further evidence for a component
peaking at 2.55 GeV. The non- contribution is close to phase
space; it peaks at 2.6 GeV and is very different from .Comment: 15 pages, 6 figures, 1 table, Submitted to PL
Measurements of the observed cross sections for exclusive light hadron production in e^+e^- annihilation at \sqrt{s}= 3.773 and 3.650 GeV
By analyzing the data sets of 17.3 pb taken at GeV
and 6.5 pb taken at GeV with the BESII detector at the
BEPC collider, we have measured the observed cross sections for 12 exclusive
light hadron final states produced in annihilation at the two energy
points. We have also set the upper limits on the observed cross sections and
the branching fractions for decay to these final states at 90%
C.L.Comment: 8 pages, 5 figur
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