Health state utility data in Cystic Fibrosis: A systematic review

Introduction: Cystic fibrosis (CF) is a life-limiting, hereditable condition, with the highest prevalence in Europe. CF treatments have led to improvements in clinical symptoms, disease management and decelerated disease progression. However, little is known about the health state utility (HSU) associated with CF disease states, adverse events, and changes in disease severity. Although HSU data have contributed to existing health economic modelling studies, a lack of such data have been highlighted. This systematic review aims to provide a summary of HSU-related research in CF and highlight related research gaps. Methods: Online searches were performed in six databases and studies in any of the following categories were included: (1) estimation of HSUs in CF; (2) mapping studies between patient-reported outcome measures (PROMs) and HSUs; (3) economic evaluations on the management of CF that report primary HSU data; and (4) any CF clinical trial that reported HSU as an outcome. Results: A total of 17 studies were reviewed, of which 12 provided HSU values for specific CF populations. The remaining five articles provided HSU data that were broken down by CF relevant health states, including lung transplantations, pulmonary exacerbation (PEx) events and forced expiratory volume in 1 s (FEV 1). Conclusion: Current HSU data in CF are limited and there is considerable scope for further research, both in providing HSU values for CF and in investigating methods for HSU elicitation/evaluation in CF populations

Ecological Crisis, or “Intersex Panic,” as Answer of the Real?

Drawing upon Cal’s eventual metamorphosis into “The [white] Man” in Middlesex, and an examination of the Real of ecological crisis, Hsu explores the intersection of environmental racism, climate change denial, and intersex discrimination in order to advocate for a renewed awareness of ecological interdependency and the need for self-determination of people of colour in ecological and environmental justice discourses

Private Pareto Optimal Exchange

We consider the problem of implementing an individually rational, asymptotically Pareto optimal allocation in a barter-exchange economy where agents are endowed with goods and have preferences over the goods of others, but may not use money as a medium of exchange. Because one of the most important instantiations of such economies is kidney exchange -- where the "input"to the problem consists of sensitive patient medical records -- we ask to what extent such exchanges can be carried out while providing formal privacy guarantees to the participants. We show that individually rational allocations cannot achieve any non-trivial approximation to Pareto optimality if carried out under the constraint of differential privacy -- or even the relaxation of \emph{joint} differential privacy, under which it is known that asymptotically optimal allocations can be computed in two-sided markets, where there is a distinction between buyers and sellers and we are concerned only with privacy of the buyers~\citep{Matching}. We therefore consider a further relaxation that we call \emph{marginal} differential privacy -- which promises, informally, that the privacy of every agent $i$ is protected from every other agent $j \neq i$ so long as $j$ does not collude or share allocation information with other agents. We show that, under marginal differential privacy, it is possible to compute an individually rational and asymptotically Pareto optimal allocation in such exchange economies

A supplement to an EOQ model with imperfect quality items, inspection errors, shortage backordering, and sales return

Hsu and Hsu (2013a) established a closed-form solution for an EOQ model with imperfect quality items, inspection errors, shortage backordering, and sales returns, where the customers who return the defective items will receive full price refunds; i.e., the returned items are not replaced with good items. In this note, we extend Hsu and Hsu's (2013a) work to consider the case that returned items are replaced with good items. A closed-form solution is developed for the optimal order size and the maximum shortage level. Numerical examples are provided to show the differences in the optimal solutions when returned items are replaced, and when they are not

High Density Effective Theory Confronts the Fermi Liquid

The high density effective theory recently introduced by Hong and Hsu to describe ultradense relativistic fermionic matter is used to calculate the tree-level forward scattering amplitude between two particles at the Fermi surface. While the direct term correctly reproduces that of the underlying gauge theory, the exchange term has the wrong sign. The physical consequences are discussed in the context of Landau's theoretical description of the Fermi liquid.Comment: 15 pages, 2 figures; conclusion expanded, reference adde

Skill development and the making of the global citizen: an analysis of student experiences with study abroad at Humboldt State University

Global citizenship is seen as an emerging necessity as work places are shifting to a more global environment and as challenges we face are becoming more global in nature. This thesis focuses on the creation and nurturing of global citizenship through participation in study abroad programming at Humboldt State University (HSU). Research has shown participation in study abroad has an impact on the participant’s skill development (Farraguia and Sanger 2017) and such skill development can be applied to advancement of global citizenship. This thesis utilizes a mixed methodology to develop a thorough understanding of the level of skills associated with studying abroad for HSU students. Spatial data was examined to determine the extent to which HSU students were studying abroad in the same countries as students across the United States. A survey was sent out to 75 recent HSU study abroad participants and a random sample of 350 HSU students to determine global perspectives. Finally, semi-structured face-to-face interviews were conducted with eight students returning from study abroad programs in order to detail how the skills they developed impacted their lives. Europe was the most popular region for both HSU and US study abroad in the 2017/2018 academic year. Survey data indicated study abroad participation increases identification as a global citizen, and the interviewees commonly referenced food in describing the skills they developed from their study abroad experiences

Check Out the Library, 2016 Spring Issue

Issue 2 HSU Library Seismic Retrofit Project Update We’re Becoming So Popular! Technology at the Checkout Desk News from the Lower Library: Learning Center Showcases Alumni Students are Talking! Library Skillshops Astronomy: A Cultural Gaze from Latin America at the HSU Library Upcoming Eventshttps://digitalcommons.humboldt.edu/library_pub/1012/thumbnail.jp