A Study on the Factors Influencing the Intention of Reusing an eCommerce Website

A customer’s intention of reusing an e-commerce website for shopping has a great consequence for the website’s profitability; therefore, understanding the factors that influence a Web-customer’s reuse intention is of great importance to e-commerce. This study examines the influencing factors by constructing an integrated model with the Motivation Hub and the Expectancy Disconfirmation Theory, and adopting the constructs of general and specific Internet self-efficacy, perceived performance, disconfirmation, satisfaction, and reuse intention. Six research hypotheses derived from the integrated model were validated by EQS using a field survey of the users of top 100 e-commerce websites in Taiwan. The academic implication of this study is that the integrated model explains the factors that influence Web-customers’ reuse intention. For practical application, the e-commerce companies can adopt the research outcomes to ensure the success of their websites

Effects of Growth Hormone Treatment on Height, Weight, and Obesity in Taiwanese Patients with Prader-Willi Syndrome

BackgroundInformation regarding the efficacy of growth hormone (GH) therapy in Asian Prader-Willi syndrome (PWS) patients is lacking. We report our experience with GH treatment in children with PWS in Taiwan.MethodsForty-six PWS patients (27 males, 19 females; age range, 1 year 4 months to 13 years 7 months) who received and/or who are currently receiving GH treatment (0.1 IU/kg/day subcutaneously) for a period from 1 year to 3 years were retro-spectively analyzed. We evaluated height, weight, body mass index (BMI) and Rohrer index, before and after GH treatment.ResultsAfter patients had received GH for 1, 2 and 3 years, a significant improvement in mean height standard deviation score (SDS) was noted from −1.24 to −0.31 (p <0.01), 0.00 (p <0.001) and −0.26 (p <0.001), respectively. Mean BMI SDS decreased significantly from 1.93 to 1.13 (p <0.05) after 1 year of treatment; however, no significant changes were observed afterward. Mean Rohrer index decreased significantly, from 224.2 to 186.6 (p <0.001), 178.9 (p <0.001) and 169.3 (p <0.001). No significant gender or genotype pattern differences were noted among the 4 parameters examined.ConclusionThis 3-year, retrospective study indicates that PWS patients benefit from GH therapy in height increase and improved body composition

A testis-specific regulator of complex and hybrid N-glycan synthesis

GnT1IP inhibits GlcNAcT-1 to change N-glycosylation patterns on secretory proteins, potentially regulating germ cell adhesion to Sertoli cells during spermatogenesis

Nationwide Surveillance of Influenza during the Pandemic (2009–10) and Post-Pandemic (2010–11) Periods in Taiwan

INTRODUCTION: Although WHO declared the world moving into the post-pandemic period on August 10, 2010, influenza A(H1N1) 2009 virus continued to circulate globally. Its impact was expected to continue during the 2010-11 influenza season. This study describes the nationwide surveillance findings of the pandemic and post-pandemic influenza periods in Taiwan and assesses the impact of influenza A(H1N1) 2009 during the post-pandemic period. METHODS: The Influenza Laboratory Surveillance Network consisted of 12 contract laboratories for collecting and testing samples with acute respiratory tract infections. Surveillance of emergency room visits and outpatient department visits for influenza-like illness (ILI) were conducted using the Real-Time Outbreak and Disease Surveillance system and the National Health Insurance program data, respectively. Hospitalized cases with severe complications and deaths were reported to the National Notifiable Disease Surveillance System. RESULTS: During the 2009-10 influenza season, pandemic A(H1N1) 2009 was the predominant circulating strain and caused 44 deaths. However, the 2010-11 influenza season began with A(H3N2) being the predominant circulating strain, changing to A(H1N1) 2009 in December 2010. Emergency room and outpatient department ILI surveillance displayed similar trends. By March 31, 2011, there were 1,751 cases of influenza with severe complications; 50.1% reported underlying diseases. Of the reported cases, 128 deaths were associated with influenza. Among these, 93 (72.6%) were influenza A(H1N1) 2009 and 30 (23.4%) A(H3N2). Compared to the pandemic period, during the immediate post-pandemic period, increased number of hospitalizations and deaths were observed, and the patients were consistently older. CONCLUSIONS: Reemergence of influenza A(H1N1) 2009 during the 2010-11 influenza season had an intense activity with age distribution shift. To further mitigate the impact of future influenza epidemics, Taiwan must continue its multifaceted influenza surveillance systems, remain flexible with antiviral use policies, and revise the vaccine policies to include the population most at risk

Studying the Settlement of OWT Monopile Foundations Using a T-Z Spring with the Torsional Effect

The main purpose of this paper was to study the vertical settlement of offshore wind turbine (OWT) monopile support structures, where 5, 10, 15, and 20 MW OWT support structures were analyzed under power production, seismic, and tropical cyclone loads. Moreover, a t-z spring with shear and torsional degrees of freedom was developed to simulate the shear stress along the pile and soil surface under the combined effect of vertical loads and z-direction torsions. This t-z spring does not require excessive changes to the finite element program, where only a known factor is used to modify the traditional stiffness of the t-z spring. This paper, analyzing several kinds of OWT monopile foundations, indicates that the soil shear resistance may be less than the shear stress generated by the combination of vertical loads and torsions, which causes large vertical and rotational displacements resulting in the failure of monopile structures. This situation will be worse when the natural frequency of the first vertical-direction rotation is close to the integer multiples of the 3P frequency, which cannot be well-simulated using traditional t-z springs

Studying the Settlement of OWT Monopile Foundations Using a T-Z Spring with the Torsional Effect

The main purpose of this paper was to study the vertical settlement of offshore wind turbine (OWT) monopile support structures, where 5, 10, 15, and 20 MW OWT support structures were analyzed under power production, seismic, and tropical cyclone loads. Moreover, a t-z spring with shear and torsional degrees of freedom was developed to simulate the shear stress along the pile and soil surface under the combined effect of vertical loads and z-direction torsions. This t-z spring does not require excessive changes to the finite element program, where only a known factor is used to modify the traditional stiffness of the t-z spring. This paper, analyzing several kinds of OWT monopile foundations, indicates that the soil shear resistance may be less than the shear stress generated by the combination of vertical loads and torsions, which causes large vertical and rotational displacements resulting in the failure of monopile structures. This situation will be worse when the natural frequency of the first vertical-direction rotation is close to the integer multiples of the 3P frequency, which cannot be well-simulated using traditional t-z springs

Donor–Acceptor Random Copolymers Based on a Ladder-Type Nonacyclic Unit: Synthesis, Characterization, and Photovoltaic Applications

We have developed a ladder-type multifused thienyl–phenylene–thienylene–phenylene–thienyl (TPTPT) unit where each thiophene ring is covalently fastened with the adjacent benzene rings by a carbon bridge, forming four cyclopentadiene rings embedded in a nonacyclic structure. This rigid and coplanar TPTPT building block was copolymerized with electron-deficient acceptors, dibromobenzothiadiazole (BT) or dibromodithienyldiketopyrrolopyrrole (DPP), via Stille polymerization. By varying the feed ratio of the monomers, a new series of random copolymers PTPTPTBT11, PTPTPTBT12, PTPTPTDPP11, PTPTPTDPP12, and PTPTPTDPP13 with tunable optical and electronic properties were prepared. The PTPTPTDPP12/PC₇₁BM (1:4, w/w) based device exhibited the highest short circuit current (<i>J</i>_sc) of 10.78 mA/cm² with a good power conversion efficiency (PCE) of 4.3% due to the much boarder absorption ability and the highest hole mobility of PTPTPTDPP12. The devices based on PTPTPTDPP13, PTPTPTDPP11, PTPTPTBT12, and PTPTPTBT11 polymers also displayed promising efficiencies of 4.1%, 3.6%, 3.1%, and 2.8%, respectively. Most importantly, PTPTPTDPP12 has been demonstrated as a superior low-band-gap material for polymer solar cell with inverted architecture, achieving a high PCE of 5.1%

Review of Animal Models to Study Urinary Bladder Function

The urinary bladder (UB) serves as a storage and elimination organ for urine. UB dysfunction can cause multiple symptoms of failure to store urine or empty the bladder, e.g., incontinence, frequent urination, and urinary retention. Treatment of these symptoms requires knowledge on bladder function, which involves physiology, pathology, and even psychology. There is no ideal animal model for the study of UB function to understand and treat associated disorders, as the complexity in humans differs from that of other species. However, several animal models are available to study a variety of other bladder disorders. Such models include animals from rodents to nonhuman primates, such as mice, rats, rabbits, felines, canines, pigs, and mini pigs. For incontinence, vaginal distention might mimic birth trauma and can be measured based on leak point pressure. Using peripheral and central models, inflammation, bladder outlet obstruction, and genetic models facilitated the study of overactive bladder. However, the larger the animal model, the more difficult the study is, due to the associated animal ethics issues, laboratory facility, and budget. This review aims at facilitating adapted animal models to study bladder function according to facility, priority, and disease