Caffeine effect on extending time to exhaustion

The purpose of this study was to determine the effect of different doses of caffeine on extending time to exhaustion in long-term endurance exercise. Using a placebo-controlled, double-blind crossover study design, 10 hobby male cyclists (30.3 ± 5.8 y; BMI = 23.5 ± 1.6, VO2max = 56.9 ± 6.6 ml x kg⁸¹ x min⁸¹) completed three experimental tests. Each test consisted of 1-h steady-state cycling on static ergometer at 70% VO2max load immediately followed by graded exercise test to exhaustion (2.3 W x s⁸¹). Either placebo or 0 or 7 mg x kg⁸¹ BM of synthetic caffeine with 0.5 l water and maximum of 0.5 mg x kg⁸¹ BM of carbohydrate gel were administered 70 minutes prior to the test. Total exercise time was significantly (p < 0.05) extended by the 7 mg x kg⁸¹ BM of caffeine compared with placebo. Significant (p < 0.05) extension of total exercise time was observed also by the 7 mg x kg⁸¹ compared with 2 mg x kg⁸¹. No statistically (p = 0.97) significant differences were observed between 2 mg x kg⁸¹ compared with placebo. Positive effect of caffeine on long-term endurance in hobby cyclist was observed only after ingestion of high dosage (7 mg x kg⁸¹ BM). Low dosage (2 mg x kg⁸¹) didn’t show any ergogenic effect compared with placebo. This result might not be generalized, but rather shows ambiguous effects of this substance

Evaluation Of The Pioneer Exercise Training Program For People With High Risk Of Cardiovascular Disease

Cílem sdělení je představit pilotní 3měsíční pohybový program zaměřený na III. a IV. fázi kardiovaskulární rehabilitace. Programu se zúčastnilo 6 osob (58±9 let) po akutním infarktu myokardu s nekomplikovaným průběhem, s provedenou revaskularizací myokardu. Pilotní projekt Fakulty sportovních studií, I. interní kardiologické kliniky Lékařské fakulty Masarykovy univerzity a rehabilitačního oddělení Fakultní nemocnice Brno v současnosti pokračuje druhým 3měsíčním programem. Ukázala se zde potřeba vytvořit pevnější návaznost na posthospitalizační rehabilitační fázi.The goal of the study was to introduce the 3-month fitness programme particularly focused on the III. and IV.  stage of cardiovascular rehabilitation.  Six persons (58 ± 9 years), who all had post-acute myocardial infarction undertook the program. The subjects had an uncomplicated history and had underwent myocardial revascularisation. It is important to note, that this mutual pilot project of the Faculty of Sports Studies, was endorsed by Internal cardiology clinics and Department of Rehabilitative Medicine in University hospital Brno. These particular departments indicated the need to establish a stronger continuity to the hospital rehabilitation programme. Currently, the pilot project has been successfully followed by its second 3-month programme

The Effect of Respiratory and Physical Intervention on Selected Parameters of Heart Rate Variability in Hematooncological Patients after Treatment

The aim of this research was to determine the effect of respiratory and physical intervention for twelve weeks on selected parameters of heart rate variability in hematooncological patients after treatment. Spectral analysis of heart rate variability was measured by DiANS PF8 machine with Medical DiANS PC software. Evaluated were complex indices – Total score and Sympathovagal balance (S-V balance). The intervention programme was composed of three months of respiratory training and then three months of physical training. The experimental group, which absolved this combination of respiratory and physical intervention, was assessed at free time points: firstly, before the respiratory intervention, secondly between the respiratory and the physical intervention and thirdly after the physical intervention. The control group (without intervention) was measured twice between six months. 30 hematooncological patients (16 women and 14 men) were participated in this research, ranging in age 53,74±14,76 years from Internal Hematology and Oncology Clinic of The University Hospital Brno. Results of selected parameters of heart rate variability showed improvements, but without statistically significant effect of the intervention programme

Pohybová aktivita jako účinný prostředek nefarmakologické péče v onkologii

Title in English: Physical activity as an effective means of non-pharmacological care in oncology. Much of the existing research confirms the assumption that regular physical activity can play a crucial role in nonpharmacological therapy and quality of life management in cancer survivors. The treatment of oncological diseases itself brings about numerous undesirable side effects, such as cardiotoxicity, anxiety, depression, sarcopenia, polyneuropathy, cancer fatigue and sleep disorders. Regular physical activity is associated with significant benefits for health including a lower risk of developing certain types of tumours and elimination of the accompanying undesirable effects of oncological treatment. A number of epidemiological studies found a correlation between regular physical activity and lower mortality linked to oncological diseases. The minimal amount of the activity needed to gain this benefit has not been established, however, the recommendations of ACSM indicate that at least 150 minutes of moderate physical activity are needed per week. Physical exercise as nonpharmacological treatment is a domain of cancer survivors therapy whose aim is to incorporate targeted controlled exercise programmes into the overall treatment plan of the patients. Exercise programmes can be performed both in the duration of the illness as well as in the period prior to the treatment or in the course of adjuvant antitumour treatment (including chemotherapy) and in survivors. When prescribing physical activity it is necessary to take current health condition of the patient into account including their comorbidities, age or the level of physical fitness. If controlled physical activity is to become an indispensable part of oncological treatment it will be necessary to prove the therapy is safe and cost-effective

Proceedings of the 12th International Conference on Kinanthropology

Proceedings of the 12th Conference of Sport and Quality of Life 2019 gatheres submissions of participants of the conference. Every submission is the result of positive evaluation by reviewers from the corresponding field. Conference is divided into sections – Analysis of human movement; Sport training, nutrition and regeneration; Sport and social sciences; Active ageing and sarcopenia; Strength and conditioning training; section for PhD students

Physical intervention as a means of increasing the condition of haemato-oncological survivors in subsequent care

The main aim of the interventional motion and respiratory programme is increasing fitness in hemato-oncological patients as well as cessation of their muscle mass loss as a result of their disease and treatment. Hemato-oncological diseases and their treatment bring a range of side effects that are caused by cardiac, neural, and pulmonary toxicity of the treatment, which has influence upon the decreasing quality of the patients´ lives. Studies indicate that physical exercise, especially of aerobic character, increase cardio-respiratory fitness, muscle strength, and physical well-being. The motion and respiratory interventional programme took place over a period of 6 months. It was divided into a 3 months respiratory training at home and a directed motion aerobic programme that took place 3 times a week for 60 minutes. The intensity of the exercise was set up individually on the level of the anaerobic threshold of each participant, which was ascertained on the basis of the initial performance test. The research sample were 16 people, mean age value was 53.31 years of age. The results of the performance tests after the motion and respiratory programme of the participants of the study showed improvements in the field of the participants´ aerobic capacity as well as in the field of sympto-vagal disbalance unfortunately without statistical significance. There is still an open scientific question regarding the most effective types of physical intervention in terms of their influence on the health of surviving hemato-oncological patients.Hlavním cílem intervenčního pohybového a respiračního programu je zvýšit kondici u hematoonkologických pacientů, stejně jako zmírnit ztráty svalové hmoty, které jsou důsledkem nemoci a léčby ovlivněny. Hematoonkologická onemocnění a jejich léčba přinášejí řadu vedlejších efektů. Například srdeční, nervová a plicní toxicita, způsobená léčbou, má vliv na snížení kvality života pacientů. Studie ukazují, že cvičení, zejména aerobního charakteru, zvyšuje srdeční respirační zdatnost, svalovou sílu a fyzickou pohodu. Náš pohybový a respirační intervenční program probíhal po dobu 6 měsíců. Byl rozdělen do 3 měsíčního respiračního tréninku doma a na aerobní program s řízeným pohybem, který se konal třikrát týdně po dobu 60 minut. Intenzita cvičení byla stanovena individuálně na úrovni anaerobního prahu každého účastníka, který byl zjištěn na základě počátečního testu výkonnosti. Výzkumný soubor tvořilo 16 osob, průměrný věk byl 53,31 let. Výsledky výkonnostních testů po pohybovém a respiračním programu účastníků studie ukázaly zlepšení v oblasti aerobní kapacity účastníků i v oblasti sympatovagové rovnováhy, bohužel bez statistické významnosti. Stále existuje nezodpovězená otázka týkající se nejúčinnějších typů fyzické intervence z hlediska jejich vlivu na zdraví hematoonkologických pacientů v následné péči

The effectiveness of three mobile-based psychological interventions in reducing psychological distress and preventing stress-related changes in the psycho-neuro-endocrine-immune network in breast cancer survivors: Study protocol for a randomised controlled trial

Background: A growing body of literature shows that psychological distress is not only a major threat to psychological well-being but can also have a significant impact on physical health. In cancer patients, it can negatively affect prognosis and posttreatment recovery processes. Since face-to-face psychological interventions are often inaccessible to cancer patients, researchers have recently been focusing on the effectiveness of eHealth adaptations of well-established approaches. In this context, there has been a call for high-quality randomised controlled trials that would allow for a direct comparison of different approaches, potentially addressing different needs and preferences of patients, and also for more systematic research focusing on how psychological interventions affect not only psychological but also biological markers of stress. Both of these questions are addressed in the present study. Methods: A randomised controlled trial will be carried out to test and compare the effectiveness of three eight-week eHealth programmes for the mental health support of cancer patients. All programmes will be delivered through the same application for mobile devices MOU MindCare. N = 440 of breast cancer survivors will be recruited at the end of their adjuvant treatment (chemotherapy, radiotherapy, or both) and randomly assigned to one of the three interventions – Mindfulness-Based Cognitive Therapy for Cancer (MBCT-Ca), Positive Psychology (PP), or Autogenic Training (AT) – or the treatment-as-usual (TAU) control group. Psychological and biological markers of stress and adaptive functioning will be assessed at baseline (T0), post-treatment (T1), three-month follow-up (T2), and nine-month follow-up (T3). Primary outcomes will include heart-rate variability and self-report measures of depression, anxiety, perceived stress, general quality of life, and positive mental health. Secondary outcomes will include the levels of serum cortisol and immunomarkers, sleep quality, fatigue, common health symptoms, and several transdiagnostic psychological variables that are expected to be specifically affected by the MBCT-Ca and PP interventions, including dispositional mindfulness, emotion regulation, self-compassion, perceived hope, and gratitude. The data will be analysed using the mixed model repeated measures (MMRM) approach. Discussion: This trial is unique in comparing three different eHealth interventions for cancer patients based on three well-established approaches to mental health support delivered on the same platform. The study will allow us to examine whether different types of interventions affect different indicators of mental health. In addition, it will provide valuable data regarding the effects of stress-reducing psychological interventions on the biomarkers of stress playing an essential role in cancer recovery processes and general health