Light Field Reconstruction via Attention-Guided Deep Fusion of Hybrid Lenses

This paper explores the problem of reconstructing high-resolution light field (LF) images from hybrid lenses, including a high-resolution camera surrounded by multiple low-resolution cameras. The performance of existing methods is still limited, as they produce either blurry results on plain textured areas or distortions around depth discontinuous boundaries. To tackle this challenge, we propose a novel end-to-end learning-based approach, which can comprehensively utilize the specific characteristics of the input from two complementary and parallel perspectives. Specifically, one module regresses a spatially consistent intermediate estimation by learning a deep multidimensional and cross-domain feature representation, while the other module warps another intermediate estimation, which maintains the high-frequency textures, by propagating the information of the high-resolution view. We finally leverage the advantages of the two intermediate estimations adaptively via the learned attention maps, leading to the final high-resolution LF image with satisfactory results on both plain textured areas and depth discontinuous boundaries. Besides, to promote the effectiveness of our method trained with simulated hybrid data on real hybrid data captured by a hybrid LF imaging system, we carefully design the network architecture and the training strategy. Extensive experiments on both real and simulated hybrid data demonstrate the significant superiority of our approach over state-of-the-art ones. To the best of our knowledge, this is the first end-to-end deep learning method for LF reconstruction from a real hybrid input. We believe our framework could potentially decrease the cost of high-resolution LF data acquisition and benefit LF data storage and transmission.Comment: 14 pages, 8 figures. arXiv admin note: text overlap with arXiv:1907.0964

Learning Light Field Angular Super-Resolution via a Geometry-Aware Network

The acquisition of light field images with high angular resolution is costly. Although many methods have been proposed to improve the angular resolution of a sparsely-sampled light field, they always focus on the light field with a small baseline, which is captured by a consumer light field camera. By making full use of the intrinsic \textit{geometry} information of light fields, in this paper we propose an end-to-end learning-based approach aiming at angularly super-resolving a sparsely-sampled light field with a large baseline. Our model consists of two learnable modules and a physically-based module. Specifically, it includes a depth estimation module for explicitly modeling the scene geometry, a physically-based warping for novel views synthesis, and a light field blending module specifically designed for light field reconstruction. Moreover, we introduce a novel loss function to promote the preservation of the light field parallax structure. Experimental results over various light field datasets including large baseline light field images demonstrate the significant superiority of our method when compared with state-of-the-art ones, i.e., our method improves the PSNR of the second best method up to 2 dB in average, while saves the execution time 48$\times$. In addition, our method preserves the light field parallax structure better.Comment: This paper was accepted by AAAI 202

Description of a new species of Forcipomyia (Euprojoannisia) Brèthes, 1914 (Diptera: Ceratopogonidae) and a key to Chinese species of the subgenus

Forcipomyia (Euprojoannisia) coronacella Han et Hou sp. n. (Diptera: Ceratopogonidae) is described and illustrated based on male specimens from China. The new species is compared with the similar congeners, F. (Euprojoannisia) palustris (Meigen, 1804) and F. (Euprojoannisia) mucronis Liu et Yu, 2001. We provide separate keys for identification of the males and females of the species of the subgenus F. (Euprojoannisia) Brèthes in China

{6-[2,5-Bis(chloro­meth­yl)-3,4-dihydroxy­tetra­hydro­furan-2-yl­oxy]-3-chloro-4,5-dihydr­oxy-3,4,5,6-tetra­hydro-2H-pyran-2-yl}methyl acetate dihydrate

The title compound, C14H21Cl3O9·2H2O, is a disaccharide constructed from a galactose and a fructose. In the mol­ecular structure, the tetra­hydro­furan five-membered ring and tetra­hydro­pyran six-membered ring assume envelope and chair conformations, respectively. An extensive O—H⋯O hydrogen-bonding network occurs in the crystal structure

No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients

<p>Abstract</p> <p>Background</p> <p>Mast cells promote the progression of experimental tumors and might be a valuable therapeutic target. However, the relevant clinical evidence is still controversial. This study analyzed the relationship between the distribution of mast cells and the survival of patients with colon cancer to study whether mast cells contribute to tumor progression.</p> <p>Materials and methods</p> <p>Ninety-three cases of pathologically confirmed primary cancer tissues matched with adjacent normal mucosa, metastases of regional-draining lymph nodes and regional-draining lymph nodes without metastases were collected from stage IIIB colon carcinoma patients between January 1997 and July 2004 at the Cancer Center of Sun Yat-Sen University. Tryptase-positive mast cells were counted. The relationships of the distribution of mast cells with clinicopathologic parameters and 5-year survival were analyzed.</p> <p>Results</p> <p>Although the mast cell count in the mucosa adjacent to the primary colon cancer was significantly higher than that in the stroma of the primary colon cancer, no difference in mast cell counts was observed between the stroma in lymph node metastasis and the lymph tissue adjacent to the metastasis. Additionally, the mast cell count in the regional-draining lymph node without the invasion of cancer cells was significantly higher than that in the stroma of lymph node metastasis and adjacent lymph tissue. However, none of those mast cell counts was related to 5-year survival.</p> <p>Conclusion</p> <p>Although mast cell count varied with location, none of the mast cell counts was related to 5-year survival, suggesting that mast cells do not contribute to the progression of stage IIIB colon cancer.</p

Research Progress on the Relevance between Intestinal Flora and Colorectal Cancer

Cancer is a common chronic disease all over the world, which will cause serious health burden. At present, the debate about the role of intestinal flora in the prevention and control of cancer has always existed. Therefore, researchers should pay close attention to the impact of intestinal flora on several cancers (such as colon cancer, liver cancer and breast cancer). In addition, it is reported that intestinal flora may also affect the efficacy of cancer chemotherapy and immunotherapy. This paper introduces some energy research results to help clear the relationship between intestinal flora and cancer, even cancer micro environment. It can help clarify the mist of cancer and gut microbiota, let those little creatures to serve the progress of improving mankind living condition and of health and medicine

Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinoma

<p>Abstract</p> <p>Background</p> <p>The oncoprotein Epstain-Barr Virus (EBV)-encoded latent membrane protein1 (LMP1) modulates the pathological effects of the NF-κB, AP-1 and JAK/STAT pathways in nasopharyngeal carcinoma (NPC).</p> <p>Methods</p> <p>Microarray analysis was performed on the NPC cell line HONE1 stably transfected with a LMP1-expression plasmid or an empty vector. Based on assigned pathways analyzed using the KEGG database, the mTOR signaling pathway was selected for verification by quantitative RT-PCR. Western blot, RNA interference and immunofluorescence were used to determine the relationship between LMP1 and mTOR signing pathway genes, and their clinical significance to NPC.</p> <p>Results</p> <p>Our studies revealed that overexpression of LMP1 upregulated the mTOR signaling pathway, possibly through phosphorylation of AKT/mTOR/P70S6K/4EBP1 in the NPC cell lines HONE1 and 6-10B. Knockdown of LMP1 reduced expression of p-mTOR and p-4EBP1 in EBV-positive NPC cell line C666-1. In addition, LMP1 expression closely correlated with expression of p-mTOR, p-P70S6K and p-4EBP1 in NPC tumors. Expression of p-P70S6K, p-4EBP1 and LMP1, but not p-mTOR, significantly correlated with overall survival of NPC patients. However, only LMP1 was an independent prognostic factor.</p> <p>Conclusions</p> <p>These results suggest that the mTOR signaling pathway is regulated by LMP1 expression in NPC. LMP1 and the genes in the mTOR pathway such as p-P70S6K and p-4EBP1 may be potential prognostic biomarkers.</p

T cell immunity rather than antibody mediates cross-protection against Zika virus infection conferred by a live attenuated Japanese encephalitis SA14-14-2 vaccine.

Zika virus (ZIKV) and Japanese encephalitis virus (JEV) are closely related to mosquito-borne flaviviruses. Japanese encephalitis (JE) vaccine SA14-14-2 has been in the Chinese national Expanded Program on Immunization since 2007. The recent recognition of severe disease syndromes associated with ZIKV, and the identification of ZIKV from mosquitoes in China, prompts an urgent need to investigate the potential interaction between the two. In this study, we showed that SA14-14-2 is protective against ZIKV infection in mice. JE vaccine SA14-14-2 triggered both Th1 and Th2 cross-reactive immune responses to ZIKV; however, it was cellular immunity that predominantly mediated cross-protection against ZIKV infection. Passive transfer of immune sera did not result in significant cross-protection but did mediate antibody-dependent enhancement in vitro, though this did not have an adverse impact on survival. This study suggests that the SA14-14-2 vaccine can protect against ZIKV through a cross-reactive T cell response. This is vital information in terms of ZIKV prevention or precaution in those ZIKV-affected regions where JEV circulates or SA14-14-2 is in widespread use, and opens a promising avenue to develop a novel bivalent vaccine against both ZIKV and JEV. KEY POINTS: • JEV SA14-14-2 vaccine conferred cross-protection against ZIKV challenge in mice. • T cell immunity rather than antibody mediated the cross-protection. • It provides important information in terms of ZIKV prevention or precaution

Expression of chemokine receptor CXCR4 in nasopharyngeal carcinoma: pattern of expression and correlation with clinical outcome

Nasopharyngeal carcinoma (NPC) is a tumor derived from epithelial cells and Epstein-Barr virus infection has been reported to be a cause of this disease. Chemokine receptor CXCR4 was found to be involved in HIV infection and was highly expressed in human malignant breast tumors and the ligand for CXCR4, CXCL12 (SDF-1), exhibited high expression in organs in which breast cancer metastases are often found. The metastatic pattern of NPC is quite similar to that of malignant breast tumors. In this study, we investigated the expression of CXCR4 in nasopharyngeal carcinoma (NPC) tissues by immunohistostaining. We found different staining patterns, which included localization in the nucleus, membrane, cytoplasm or a combination of them. The staining intensity was also variable among samples. The metastatic rates in patients with high compared to low or absent expression was 38.6% versus 19.8%, respectively (P = 0.004). High expression of CXCR4 was associated with poor overall survival (OS = 67.05% versus 82.08%, P = 0.0225). These results suggest that CXCR4 may be involved in the progression of NPC and that a high level of CXCR4 expression could be used as a prognostic factor