52 research outputs found

    Consolidación y restauración de revocos esgrafiados en la iglesia parroquial de Nuestra Señora de la Asunción de Traiguera

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    [EN] The intervention mentioned in the article above was carried out at the same time as the consolidation and restoration of the magnificent sgraffito work decorating the vaults of the church described below. This operation constitutes an exemplary case for the study and material analysis of sgraffito plaster before restoration even in cases where the advanced state of deterioration and the many difficulties that arose made it seem impossible to rescue it. Furthermore, it increases our knowledge of both the materiality and the iconography of sgraffito plaster tradition in the Spanish Levant.materiality and the iconography of sgraffito plaster tradition in the Spanish Levant.[ES] La intervención del artículo anterior se realizó juntamente con la consolidación y restauración del magnífico manto de esgrafiados que decora las bóvedas del templo que se presenta a continuación. Esta actuación constituye un caso ejemplar de estudio y análisis material de revocos esgrafiados previo a su rescate incluso en aquellos casos donde parecía imposible su recuperación, dado el estado de deterioro y las dificultades presentes. Representa además una aportación al conocimiento de la tradición de los revocos esgrafiados en el Levante español, tanto en su materialidad como en su iconografía.Gavenda, M.; Hosek, J.; Kopeck, J. (2005). Consolidación y restauración de revocos esgrafiados en la iglesia parroquial de Nuestra Señora de la Asunción de Traiguera. Loggia, Arquitectura & Restauración. (18):64-69. doi:10.4995/loggia.2005.3406SWORD64691

    Absolute frequencies of H13C14N hydrogen cyanide transitions in the 1.5-µm region with the saturated spectroscopy and a sub-kHz scanning laser

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    The wide span and high density of lines in its rovibrational spectrum render hydrogen cyanide a useful spectroscopic media for referencing absolute frequencies of lasers in optical communication and dimensional metrology. We determined, for the first time to the best of our knowl-edge, the molecular transitions' center frequencies of the H13C14N isotope in the range from 1526 nm to 1566 nm with 1.3 x 10-10 fractional uncertainty. We investigated the molec-ular transitions with a highly coherent and widely tunable scanning laser that was precisely referenced to a hydrogen maser through an optical frequency comb. We demon-strated an approach to stabilize the operational conditions needed to maintain the constantly low pressure of the hydro-gen cyanide to carry out the saturated spectroscopy with the third-harmonic synchronous demodulation. We demon-strated approximately a forty-fold improvement in the line centers' resolution compared to the previous result

    First results from the OSQAR photon regeneration experiment: No light shining through a wall

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    A new method to amplify the photon-axion conversions in magnetic field is proposed using a buffer gas at a specific pressure. As a first result, new bounds for mass and coupling constant for purely laboratory experiments aiming to detect any hypothetical scalars and pseudo-scalars which can couple to photons were obtained at 95% confidence level, excluding the PVLAS result newly disclaimed.Comment: 4 pages, 5 figure

    Synthesis and hybrid SAR property modeling of novel cholinesterase inhibitors

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    A library of novel 4-{[(benzyloxy)carbonyl]amino}-2-hydroxybenzoic acid amides was designed and synthesized in order to provide potential acetyl- and butyrylcholinesterase (AChE/BChE) inhibitors; the in vitro inhibitory profile and selectivity index were specified. Benzyl (3-hydroxy-4- {[2-(trifluoromethoxy)phenyl]carbamoyl}phenyl)carbamate was the best AChE inhibitor with the inhibitory concentration of IC50 = 36.05 Min the series, while benzyl {3-hydroxy-4-[(2-methoxyphenyl) carbamoyl]phenyl}-carbamate was the most potent BChE inhibitor (IC50 = 22.23 M) with the highest selectivity for BChE (SI = 2.26). The cytotoxic effect was evaluated in vitro for promising AChE/BChE inhibitors. The newly synthesized adducts were subjected to the quantitative shape comparison with the generation of an averaged pharmacophore pattern. Noticeably, three pairs of fairly similar fluorine/bromine-containing compounds can potentially form the activity cliff that is manifested formally by high structure–activity landscape index (SALI) numerical values. The molecular docking study was conducted for the most potent AChE/BChE inhibitors, indicating that the hydrophobic interactions were overwhelmingly generated with Gln119, Asp70, Pro285, Thr120, and Trp82 aminoacid residues, while the hydrogen bond (HB)-donor ones were dominated with Thr120. - stacking interactions were specified with the Trp82 aminoacid residue of chain A as well. Finally, the stability of chosen liganded enzymatic systems was assessed using the molecular dynamic simulations. An attempt was made to explain the noted differences of the selectivity index for the most potent molecules, especially those bearing unsubstituted and fluorinated methoxy grou

    First Results of the Full-Scale OSQAR Photon Regeneration Experiment

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    Recent intensive theoretical and experimental studies shed light on possible new physics beyond the standard model of particle physics, which can be probed with sub-eV energy experiments. In the second run of the OSQAR photon regeneration experiment, which looks for the conversion of photon to axion (or Axion-Like Particle), two spare superconducting dipole magnets of the Large Hadron Collider (LHC) have been used. In this paper we report on first results obtained from a light beam propagating in vacuum within the 9 T field of two LHC dipole magnets. No excess of events above the background was detected and the two-photon couplings of possible new scalar and pseudo-scalar particles could be constrained.Comment: 5 pages, 4 figures, Photon 2011 Conference, Submitted to JO
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