1,174 research outputs found
Winning the Workforce Challenge: A Report on New Jersey's Knowledge Economy
An economic and policy analysis of the New Jersey workforce. The report describes challenges facing workers and policymakers in closing the skills gap, addressing long-term unemployment, ensuring broad-scale economic opportunity, and strengthening government programs
Meeting the Needs of the Workforce in a Shifting Regional Economy
The tri-state region (New York/New Jersey/Connecticut) supports a highly complex and diverse labor market that has been subject not only to the shocking events of September 11th, 2001, but also to broad demographic and economic trends that have shaped the structure of work and the makeup of the available workforce. This paper examines the shifts that occurred in the regional economy throughout the past decade and discusses the possible implications of these changes for the Port Authority of New York and New Jersey, educational institutions, and state and local governments
Evolutionary prediction of medicinal properties in the genus <i>Euphorbia </i>L.
The current decrease of new drugs brought to the market has fostered renewed interest in plant-based drug discovery. Given the alarming rate of biodiversity loss, systematic methodologies in finding new plant-derived drugs are urgently needed. Medicinal uses of plants were proposed as proxy for bioactivity, and phylogenetic patterns in medicinal plant uses have suggested that phylogeny can be used as predictive tool. However, the common practice of grouping medicinal plant uses into standardised categories may restrict the relevance of phylogenetic predictions. Standardised categories are mostly associated to systems of the human body and only poorly reflect biological responses to the treatment. Here we show that medicinal plant uses interpreted from a perspective of a biological response can reveal different phylogenetic patterns of presumed underlying bioactivity compared to standardised methods of medicinal plant use classification. In the cosmopolitan and pharmaceutically highly relevant genus Euphorbia L., identifying plant uses modulating the inflammatory response highlighted a greater phylogenetic diversity and number of potentially promising species than standardised categories. Our interpretation of medicinal plant uses may therefore allow for a more targeted approach for future phylogeny-guided drug discovery at an early screening stage, which will likely result in higher discovery rates of novel chemistry with functional biological activity
Motif Statistics and Spike Correlations in Neuronal Networks
Motifs are patterns of subgraphs of complex networks. We studied the impact
of such patterns of connectivity on the level of correlated, or synchronized,
spiking activity among pairs of cells in a recurrent network model of integrate
and fire neurons. For a range of network architectures, we find that the
pairwise correlation coefficients, averaged across the network, can be closely
approximated using only three statistics of network connectivity. These are the
overall network connection probability and the frequencies of two second-order
motifs: diverging motifs, in which one cell provides input to two others, and
chain motifs, in which two cells are connected via a third intermediary cell.
Specifically, the prevalence of diverging and chain motifs tends to increase
correlation. Our method is based on linear response theory, which enables us to
express spiking statistics using linear algebra, and a resumming technique,
which extrapolates from second order motifs to predict the overall effect of
coupling on network correlation. Our motif-based results seek to isolate the
effect of network architecture perturbatively from a known network state
Evolutionary bursts in Euphorbia (Euphorbiaceae) are linked with photosynthetic pathway
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109954/1/evo12534.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/109954/2/evo12534-sup-0001-SuppMAT.pd
Ants Sow the Seeds of Global Diversification in Flowering Plants
Background: The extraordinary diversification of angiosperm plants in the Cretaceous and Tertiary periods has produced an
estimated 250,000–300,000 living angiosperm species and has fundamentally altered terrestrial ecosystems. Interactions
with animals as pollinators or seed dispersers have long been suspected as drivers of angiosperm diversification, yet
empirical examples remain sparse or inconclusive. Seed dispersal by ants (myrmecochory) may drive diversification as it can reduce extinction by providing selective advantages to plants and can increase speciation by enhancing geographical
isolation by extremely limited dispersal distances.
Methodology/Principal Findings: Using the most comprehensive sister-group comparison to date, we tested the hypothesis that myrmecochory leads to higher diversification rates in angiosperm plants. As predicted, diversification rates
were substantially higher in ant-dispersed plants than in their non-myrmecochorous relatives. Data from 101 angiosperm
lineages in 241 genera from all continents except Antarctica revealed that ant-dispersed lineages contained on average
more than twice as many species as did their non-myrmecochorous sister groups. Contrasts in species diversity between
sister groups demonstrated that diversification rates did not depend on seed dispersal mode in the sister group and were
higher in myrmecochorous lineages in most biogeographic regions.
Conclusions/Significance: Myrmecochory, which has evolved independently at least 100 times in angiosperms and is
estimated to be present in at least 77 families and 11 000 species, is a key evolutionary innovation and a globally important driver of plant diversity. Myrmecochory provides the best example to date for a consistent effect of any mutualism on largescale diversification
Clinical Symptoms of Skin, Nails, and Joints Manifest Independently in Patients with Concomitant Psoriasis and Psoriatic Arthritis
This study correlated assessment tools for evaluating the severity of skin, nail, and joint symptoms in patients with psoriasis (Pso) and psoriatic arthritis (PsA). Adults with plaque Pso (with or without PsA) were enrolled from four U.S. institutions. Patients were evaluated using a novel 10-area Linear Psoriasis Area and Severity Index (XL-PASI), Psoriatic Arthritis Assessment (PsAA), Psoriatic Arthritis Screening and Evaluation Questionnaire (PASE), Nail Assessment (NA) and Joint Assessment (JA) tools, Psoriasis Weighted Extent and Severity Index (PWESI), and Lattice Physician Global Assessment (LS-PGA). Correlations between assessment tools and individual items in the assessment tools were performed. Data from 180 patients (55 with PsA) were analyzed. Highest correlations between tools (r = 0.77–0.88) were between the XL-PASI, PWESI and LS-PGA. Individual items in the XL-PASI correlated with items in the PWESI for extent skin symptoms, but not for all body areas. Overall, correlations were seen between hands and feet, between face and scalp, and between buttocks, chest, and back. Only low correlation was seen between items assessing joint symptoms with items assessing skin symptoms. These data support the notion that the complex phenotype of psoriatic disease requires instruments that assess the severity of skin, nails, and joints separately
Evaluation of Services Provided to Pregnant African Refugees by Catholic Social Services Refugee Resettlement Agency in Dayton Ohio
In 2016 Public Health - Dayton and Montgomery County declared birth outcomes the number one priority in their Community Health Improvement Plan. To improve the infant mortality rate (IMR), racial disparities must be address and considerations should be given to Dayton’s newest and most vulnerable neighbors. Dayton receives between 200 and 250 refugees each year, 70% of whom are from the Democratic Republic of the Congo. African refugees have higher infant mortally and poorer birth outcomes than native populations in the U.S. Early and regular prenatal care is protective against infant mortality, and African refugees consistently report delayed and infrequent prenatal care. Five categories affect utilization of prenatal services by African refugees; migration factors, cultural factors, treatment and communication factors, socioeconomic and accessibility factors, and social and psychological factors. This paper describes the services that Catholic Social Services (CSS) Refugee Resettlement Agency provides to newly-arrived pregnant refugees and compares these services to published guidelines and best practice models. When compared, CSS provide adequate services to address socioeconomic and accessibility factors through funding provided by the Department of State. While CSS provided some services towards the other four categories, none of them are comprehensive. The acculturation process provides an opportunity for CSS to address migration and cultural factors. But it is through strong community partnerships with local stakeholders that CSS can provide comprehensive services to address all the factors that affect prenatal care utilization in African refugees
Portland Challenger-September 9, 1952
Publisher
William A. Hilliard
Editor
William A. Hilliard
Address
3300 N. Williams Avehttps://pdxscholar.library.pdx.edu/portlandchallenger/1003/thumbnail.jp
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