348 research outputs found
Production of Lignin-Based Phenolic Resins Using De-Polymerized Kraft Lignin and Process Optimization
Commercialization of Lignin-based phenol formaldehyde resins (LPF) has been limited due to the increase in curing temperatures and decrease in adhesive strength of LPF compared to conventional phenolic resins. Lignin depolymerization can increase the reactivity of lignin; however, the effect of lignin molecular weight on curing performance of LPF resins has yet to be investigated. This research work examined the optimization of synthesis parameters including percent substitution of phenol with lignin, formaldehyde- to-phenol ratio (F/P), and Mw of lignin to reduce the curing temperature and increase the adhesive strength of LPF. DSC analysis indicated that lignin with Mw ~1200g/mol resulted in lowest curing temperature for 75%-LPF while requiring F/P of less than 3. Highest adhesive strength of ~9MPa was attained for 50%-LPF synthesized with F/P of 3 and lignin with high Mw. Incorporation of lignin likely facilitated higher molecular contact and enhanced entanglement; however, it could also increase steric hindrance effects
Social impact disclosure and symbolic power : Evidence from UK Fair Trade Organizations
We thank seminar participants at Newcastle University Business School and Durham University Business School in 2019. We also thank participants at European Accounting Association Conference, Milan, 2018Peer reviewedPostprin
The accounting and accountability practices of Fairtrade International (FLO)
Peer reviewedPostprin
A Foucauldian Archaeology of Modern Medical Discourse
Indiana University-Purdue University Indianapolis (IUPUI)Medical education researchers have long been interested in understanding medical professional identity formation and its implications for the healthcare system. Various theories have been proposed to explain identity formation. Among them, Foucault’s discourse theory maintains that it is the discourse of medicine that constitutes medical professional identities. This study deployed a Foucauldian archaeological methodology to analyze the structure of modern medical discourse and establish links between discourse and professional identity formation in medical students. A total of forty-six medical students at Indiana University School of Medicine participated in either individual or focus group interviews. Direct observation of the clinical and educational settings was also performed, which resulted in additional textual data in the form of fieldnotes. Archaeological analysis of discourse was undertaken in three levels of the statements, the discursive elements, and the discursive rules and relations. Results entailed a detailed depiction of the structure of medical discourse including discursive objects and modes of enunciation, discursive concepts, and theoretical strategies related to each object. Discursive objects are things that are talked about in modern medical discourse. This study identified four discursive objects as disease and treatment, the doctor, the human body, and the sick person. Modes of enunciation are the different ways in which people talk about objects of medicine, whereas concepts consist of the notions people draw from when talking about objects of medicine. Theoretical strategies indicate certain positions that people take in relation to the objects of medicine. Rules of formation and conditions of existence for each discursive element were also established. Since Identities are
entrenched through language and interaction, developing a systematic understanding of the structure of medical discourse will shed new light on medical professional identity formation. Results of this study also have profound implications for teaching professionalism and medical humanities in medical curricula. Furthermore, as a research methodology used for the first time in medical education, archaeology not only opens new territories to be explored by future research, it also provides an entirely new way to look at them
Laser-plasma source parameters for Kr, Gd, and Tb ions at 6.6 nm
There is increasing interest in extreme-ultraviolet (EUV) laser-based lamps for sub-10-nm lithography operating in the region of 6.6 nm. A collisional-radiative model is developed as a post-processor of a hydrodynamic code to investigate emission from resonance lines in Kr, Gd, and Tb ions under conditions typical for mass-limited EUV sources. The analysis reveals that maximum conversion efficiencies of Kr occur at 5 x 10(10) W/cm(2), while for Gd and Tb it was similar or equal to 0.9%/2 pi sr for laser intensities of (2-5) x 10(12) W/cm(2)
Risk Factors for Poor Outcomes in Children Hospitalized With Virus-associated Acute Lower Respiratory Infections:A Systematic Review and Meta-analysis
BACKGROUND: Acute lower respiratory infection (ALRI) caused by respiratory viruses is among the most common causes of hospitalization and mortality in children. We aimed to identify risk factors for poor outcomes in children <5 years old hospitalized with ALRI caused by respiratory syncytial virus (RSV), influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).METHODS: We searched Embase, Medline and Global Health databases and included observational studies reporting risk factors for poor outcomes (defined as use of supplemental oxygen, mechanical ventilation, intensive care unit admission, prolonged hospital stay and mortality) published between January 2011 and January 2023. Two authors independently extracted data on study characteristics, outcomes and risk factors. Due to limited data, meta-analyses were only conducted for RSV-ALRI poor outcome risk factors using random effects model when there were at least 3 studies.RESULTS: We included 30 studies. For RSV-related ALRI, significant risk factors based on meta-analysis were: neurological disease [odds ratio (OR): 6.14; 95% confidence intervals (CIs): 2.39-15.77], Down's syndrome (5.43; 3.02-9.76), chronic lung disease (3.64; 1.31-10.09), immunocompromised status (3.41; 1.85-6.29), prematurity (2.98; 1.93-4.59), congenital heart disease (2.80; 1.84-4.24), underlying disease (2.45; 1.94-3.09), age <2 months (2.29; 1.78-2.94), age <6 months (2.08; 1.81-2.39), viral coinfection (2.01; 1.27-3.19), low birth weight (1.88; 1.19-2.95) and being underweight (1.80; 1.38-2.35). For influenza-related ALRI, chronic conditions and age 6-24 months were identified as risk factors for poor outcomes. Cardiovascular disease, immunosuppression, chronic kidney disease, diabetes and high blood pressure were reported as risk factors for mortality due to SARS-CoV-2 associated ALRI.CONCLUSIONS: These findings might contribute to the development of guidelines for prophylaxis and management of ALRI caused by RSV, influenza and SARS-CoV-2.</p
Dural Tear, a Feared Complication of Spine Surgery
OBJECTIVES
To investigate the incidence, risk factors and clinical presentation of complications in patients undergoing spinal surgery with and without Dural Tear.
METHODOLOGY
A one-year prospective case-control study was conducted in the department of orthopaedics and spinal surgery at the Hayatabad Medical Complex (HMC) and Rahman Medical and surgical centre Dagger Buner. The spine surgeon used a discrete surgical approach. The questionnaire was used to collect patient demographic data, surgical information, and data on perioperative and postoperative complications. SPSS version 21.0 statistical software was used for all statistical analyses.
RESULTS
Dural tears were observed in 3.4% of the patients, among whom 20% experienced a Dural leak. After controlling for potentially confounding variables of age, sex, primary disease, and type of procedure, the surgery-related complications that were more likely to occur in the Dural Tear group than in the non-TD group were surgical site complications OR 2.69 and postoperative neurological defect O 3.28. The proportion of postoperative delirium OR 3.22 was significantly high in the Dural Tear group as perioperative complications
CONCLUSION
A higher proportion of surgical site infections, postoperative neurological defects and delirium in the Dural Tear group are due to direct complications, such as Dural leakage
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ESPGHAN-NASPGHAN Guidelines for the Evaluation and Treatment of Gastrointestinal and Nutritional Complications in Children With Esophageal Atresia-Tracheoesophageal Fistula.
BackgroundEsophageal atresia (EA) is one of the most common congenital digestive anomalies. With improvements in surgical techniques and intensive care treatments, the focus of care of these patients has shifted from mortality to morbidity and quality-of-life issues. These children face gastrointestinal (GI) problems not only in early childhood but also through adolescence and adulthood. There is, however, currently a lack of a systematic approach to the care of these patients. The GI working group of International Network on Esophageal Atresia comprises members from ESPGHAN/NASPGHAN and was charged with the task of developing uniform evidence-based guidelines for the management of GI complications in children with EA.MethodsThirty-six clinical questions addressing the diagnosis, treatment, and prognosis of the common GI complications in patients with EA were formulated. Questions on the diagnosis, and treatment of gastroesophageal reflux, management of "cyanotic spells," etiology, investigation and management of dysphagia, feeding difficulties, anastomotic strictures, congenital esophageal stenosis in EA patients were addressed. The importance of excluding eosinophilic esophagitis and associated GI anomalies in symptomatic patients with EA is discussed as is the quality of life of these patients and the importance of a systematic transition of care to adulthood. A systematic literature search was performed from inception to March 2014 using Embase, MEDLINE, the Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Clinical Trials, and PsychInfo databases. The approach of the Grading of Recommendations Assessment, Development and Evaluation was applied to evaluate outcomes. During 2 consensus meetings, all recommendations were discussed and finalized. The group members voted on each recommendation, using the nominal voting technique. Expert opinion was used where no randomized controlled trials were available to support the recommendation
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