Self-Focused Attention and Post-Event Processing: Relevance to Social Performance Anxiety and Social Interaction Anxiety

This article originally appeared in the Journal of Cognitive Psychotherapy. The version of record is available at Springer via: http://dx.doi.org/10.1891/0889-8391.28.1.72This study examined the roles of self-focused attention and post-event processing in social performance anxiety and social interaction anxiety. College students (N = 101) completed measures of social performance anxiety, social interaction anxiety, self-focused attention, post-event processing, and beliefs related to social anxiety. Interoceptive self-focused attention and post-event processing predicted social performance anxiety after controlling for social interaction anxiety. The associations with social interaction anxiety were not significant after controlling for social performance anxiety. Associations of behavioral self-focused attention with social performance anxiety and social interaction anxiety were not significant after controlling for interoceptive self-focused attention. No evidence of an interaction between self-focused attention and post-event processing in the prediction of social anxiety was found. This study found no evidence that the associations of interoceptive self-focused attention and post-event processing with social performance anxiety were statistically mediated by high standards, conditional beliefs about self, and unconditional beliefs about self. These results and their theoretical implications are discussed

ADVANCING TUBERCULOSIS CARE THROUGH VIDEO DIRECTLY OBSERVED THERAPY (VDOT)

A central challenge in the fight against tuberculosis (TB) is overcoming the barriers presented by TB therapy, itself. Side-effects are common and treatment courses are long, extending well beyond a year in some cases of drug-resistant disease.1,2 Poor treatment adherence has been linked to microbiologic failure, disease relapse and the emergence of drug resistance.3,4 In response, and in an effort to promote treatment completion, the Centers for Disease Control (CDC) and the World Health Organization (WHO) have advocated for directly observed therapy (DOT), wherein the ingestion of each dose is directly monitored.1,5,6 In many areas, DOT is the current standard of care, though employing DOT in a patient-centered and efficient fashion can be challenging. Scheduling in-person DOT visits is logistically complicated, resource intensive (for patients and TB programs), and can increase both patient and program-level costs. In some individuals, logistical barriers and perceived stigma related to DOT have led to feelings of humiliation, loss of control and stress.7,8 To overcome these barriers, video-based DOT (vDOT) has been proposed as an alternative to in-person observation.1,9,10 Herein, pill ingestion is monitored remotely via digital video capture. vDOT has been implemented using synchronous technologies, such as Skype and FaceTime,11-14 as well as asynchronous ones, wherein recorded videos are uploaded and digitally stored for future review.15 While both the CDC and WHO support the use of vDOT, data on the real-world implementation of vDOT remains limited. To this end, we present two studies which broaden our understanding of vDOT by exploring its potential role in two distinct clinical settings, among two very different patient populations. In Chapter 1, we present the results of a pragmatic, prospective, pilot implementation of vDOT at three TB clinics in Maryland, US. A mixed-methods approach is employed to assess (1) effectiveness, (2) acceptability and (3) cost. In Chapter 2, we extend the use of vDOT into a high TB burden, low resource setting, though a prospective, pilot implementation of vDOT in Pune, India. Our work shows that vDOT may be a feasible and acceptable approach to TB treatment monitoring, both within the US and India. Further, vDOT may be associated with cost-savings within the US when compared to traditional in person DOT

CMS Software Distribution on the LCG and OSG Grids

The efficient exploitation of worldwide distributed storage and computing resources available in the grids require a robust, transparent and fast deployment of experiment specific software. The approach followed by the CMS experiment at CERN in order to enable Monte-Carlo simulations, data analysis and software development in an international collaboration is presented. The current status and future improvement plans are described.Comment: 4 pages, 1 figure, latex with hyperref

Silicon Pad Detectors for the PHOBOS Experiment at RHIC

The PHOBOS experiment is well positioned to obtain crucial information about relativistic heavy ion collisions at RHIC, combining a multiplicity counter with a multi-particle spectrometer. The multiplicity arrays will measure the charged particle multiplicity over the full solid angle. The spectrometer will be able to identify particles at mid-rapidity. The experiment is constructed almost exclusively of silicon pad detectors. Detectors of nine different types are configured in the multiplicity and vertex detector (22,000 channels) and two multi-particle spectrometers (120,000 channels). The overall layout of the experiment, testing of the silicon sensors and the performance of the detectors during the engineering run at RHIC in 1999 are discussed.Comment: 7 pages, 7 figures, 1 table, Late

Impact of extended sinus surgery on allograft infection, allograft function and overall survival in cystic fibrosis lung transplant recipients

BACKGROUND Studies investigating the impact of sinus surgery for cystic fibrosis (CF) patients performed early after lung transplantation (Ltx) are scarce. Recent studies evaluating frequency of respiratory infections and graft outcomes are not available. OBJECTIVES/HYPOTHESIS To determine whether there is a difference in allograft infection, allograft function and overall survival among CF lung transplant recipients with and without concomitant sinus surgery. STUDY DESIGN Retrospective single-center study. METHODS We examined 71 CF patients who underwent Ltx between 2009 and 2019 at our center. Fifty-nine patients had sinus surgery before or/and after transplantation and twelve did not undergo sinus surgery. We assessed the survival, the diagnosis of chronic allograft dysfunction (CLAD) and all elevated (> 5 mg/l) c-reactive protein episodes during the observed period. The infectious events of the upper and lower airways were categorized in mild infections (5-15 mg/l CRP) and severe infections (> 15 mg/l CRP). RESULTS There was no difference in the long-time overall survival (p = 0.87) and no benefit in the short-term survival at 4 year post-transplant (p = 0.29) in both groups. There was no difference in both groups concerning CLAD diagnosis (p = 0.92). The incidence of severe upper and lower airway infections (CRP > 15 mg/l) was significantly decreased in the sinus surgery group (p = 0.015), whereas in mild infections there was a trend to decreased infections in the sinus surgery group (p = 0.056). CONCLUSIONS CF patients undergoing Ltx benefit from extended endoscopic sinus surgery (eESS) in terms of frequency of severe infectious events of the upper and lower airways. There was no difference in overall survival and frequency of CLAD in the two groups

Use of glide-ins in CMS for production and analysis

With the evolution of various grid federations, the Condor glide-ins represent a key feature in providing a homogeneous pool of resources using late-binding technology. The CMS collaboration uses the glide-in based Workload Management System, glideinWMS, for production (ProdAgent) and distributed analysis (CRAB) of the data. The Condor glide-in daemons traverse to the worker nodes, submitted via Condor-G. Once activated, they preserve the Master-Worker relationships, with the worker first validating the execution environment on the worker node before pulling the jobs sequentially until the expiry of their lifetimes. The combination of late-binding and validation significantly reduces the overall failure rate visible to CMS physicists. We discuss the extensive use of the glideinWMS since the computing challenge, CCRC-08, in order to prepare for the forthcoming LHC data-taking period. The key features essential to the success of large-scale production and analysis on CMS resources across major grid federations, including EGEE, OSG and NorduGrid are outlined. Use of glide-ins via the CRAB server mechanism and ProdAgent, as well as first hand experience of using the next generation CREAM computing element within the CMS framework is discussed

The Landscape of Particle Production: Results from PHOBOS

Recent results from the PHOBOS experiment at RHIC are presented, both from Au+Au collisions from the 2001 run and p+p and d+Au collisions from 2003. The centrality dependence of the total charged particle multiplicity in p+p and d+Au show features, such as Npart-scaling and limiting fragmentation, similar to p+A collisions at lower energies. Multiparticle physics in Au+Au is found to be local in (pseudo)rapidity, both when observed by HBT correlations and by forward-backward pseudorapidity correlations. The shape of elliptic flow in Au+Au, measured over the full range of pseudorapidity, appears to have a very weak centrality dependence. Identified particle ratios in d+Au reactions show little difference between the shape of proton and anti-proton spectra, while the absolute yields show an approximate m_T scaling.Comment: 8 Pages, 11 Figures, Plenary talk at Quark Matter 2004, Oakland, CA, January 11-18, 200

From Utopia to Science: Challenges of Personalised Genomics Information for Health Management and Health Enhancement

From 1900 onwards, scientists and novelists have explored the contours of a future society based on the use of “anthropotechnologies” (techniques applicable to human beings for the purpose of performance enhancement ranging from training and education to genome-based biotechnologies). Gradually but steadily, the technologies involved migrated from (science) fiction into scholarly publications, and from “utopia” (or “dystopia”) into science. Building on seminal ideas borrowed from Nietzsche, Peter Sloterdijk has outlined the challenges inherent in this development. Since time immemorial, and at least since the days of Plato’s Academy, human beings have been interested in possibilities for (physical or mental) performance enhancement. We are constantly trying to improve ourselves, both collectively and individually, for better or for worse. At present, however, new genomics-based technologies are opening up new avenues for self-amelioration. Developments in research facilities using animal models may to a certain extent be seen as expeditions into our own future. Are we able to address the bioethical and biopolitical issues awaiting us? After analyzing and assessing Sloterdijk’s views, attention will shift to a concrete domain of application, namely sport genomics. For various reasons, top athletes are likely to play the role of genomics pioneers by using personalized genomics information to adjust diet, life-style, training schedules and doping intake to the strengths and weaknesses of their personalized genome information. Thus, sport genomics may be regarded as a test bed where the contours of genomics-based self-management are tried out