System Administration Equipment Rental Music and Sound System in Music Studio 48 with Microsoft Visual Basic 6.0

Rental of musical instruments and sound systems at 48 is still MUSIC STUDIO done manually, so based on the analysis will be needed to create a computer-based administration system in accordance with needs and desires of the leadership, particularly in terms of equipment leasing, payment receipts, and reports. Analysis performed on 48 MUSIC STUDIO through the documents and interview directly with stakeholders to obtain accurate data. The menu is presented properly designed and adjusted to the leadership desires. Starting from design input to output leasing process so as to form a report in accordance with accounting theory. This strongly supports the readiness of companies in the future when developing and audited by the auditors. Recording process is still done manually, requires a longer time compared to using computer technology

Knockout of lysosomal enzyme-targeting gene causes abnormalities in mouse pup isolation calls

Humans lacking a working copy of the GNPTAB gene suffer from the metabolic disease Mucolipidosis type II (MLII). MLII symptoms include mental retardation, skeletal deformities and cartilage defects as well as a speech delay with most subjects unable to utter single words (Otomo et al., 2009; Cathey et al., 2010; Leroy et al., 2012). Here we asked whether mice lacking a copy of Gnptab gene exhibited vocal abnormities. We recorded ultrasonic vocalizations from 5 to 8 day old mice separated from their mother and littermates. Although Gnptab(−/−) pups emitted a similar number of calls, several features of the calls were different from their wild type littermates. Gnptab(−/−) mice showed a decrease in the length of calls, an increase in the intra-bout pause duration, significantly fewer pitch jumps with smaller mean size, and an increase in the number of isolated calls. In addition, Gnptab(−/−) mice vocalizations had less power, particularly in the higher frequencies. Gnptab(+/−) mouse vocalizations did not appear to be affected. We then attempted to classify these recordings using these features to determine the genotype of the animal. We were able to correctly identify 87% of the recordings as either Gnptab(−/−) or Gnptab(+/+) pup, significantly better than chance, demonstrating that genotype is a strong predictor of vocalization phenotype. These data show that deletion of genes in the lysosomal enzyme targeting pathway affect mouse pup isolation calls

Local club condensation and L-likeness

AbstractWe present a forcing to obtain a localized version of Local Club Condensation, a generalized Condensation principle introduced by Sy Friedman and the first author in [3] and [5]. This forcing will have properties nicer than the forcings to obtain this localized version that could be derived from the forcings presented in either [3] or [5]. We also strongly simplify the related proofs provided in [3] and [5]. Moreover our forcing will be capable of introducing this localized principle at κ while simultaneously performing collapses to make κ become the successor of any given smaller regular cardinal. This will be particularly useful when κ has large cardinal properties in the ground model. We will apply this to measure how much L-likeness is implied by Local Club Condensation and related principles. We show that Local Club Condensation at κ+ is consistent with ¬☐κ whenever κ is regular and uncountable, generalizing and improving a result of the third author in [14], and that if κ ≥ ω2 is regular, CC(κ+) - Chang’s Conjecture at κ+ - is consistent with Local Club Condensation at κ+, both under suitable large cardinal consistency assumptions.</jats:p

Is the daily use of public transport facilities an enhanced epidemiological risk for diagnosing COVID-19 among healthcare workers with mild respiratory symptoms?

Introduction: Many people in Switzerland think that the daily use of the public transport facilities, during a pandemic peak wave, could be associated with an enhanced risk for Covid-19. Objectives: To investigate the association between the daily use of the public transport and acquisition of Covid-19 in Zurch during a peak wave of the pandemics. Methods: Retrospective cohort analysis of hospital-own databases at the Balgrist University Hospital in Zurich, between 1 October and 31 December 2020. We specifically interviewed our healthcare workers (HCW) about the use of public transport (with mandatory masking). Results: During the three most intensive months of the 2nd wave, we investigated 376 episodes of Covid-19-compatible respiratory symptoms and exposures among our HCW (median age 37 years), of which 94 (25%) revealed a positive PCR result for Covid-19. Overall, 225 HCW (225/376;60%) reportedly used the public transport (train, bus, tramway). In group comparison, the HCWs using the public transport system acquired no more Covid-19 than using a private transport (58/225 vs. 36/151;Pearson-chi2-test;p = 0.67). We added a logistic regression model with the outcome “Covid-19 infection” to adjust for the case-mix of different localizations or opportunities of potential contamination such as a documented exposure in the hospital, among the team members, in the family, or after a close contact to a PCR-confirmed case. In the multivariate results, using the public transport was irrelevant concerning the acquisition of Covid- 19 (odds ratio (OR) 0.98, 95%CI 0.59-1.62), in contrast, for example, to being exposed to a sick team member (OR 2.28, 95%CI 1.20-4.34). Conclusion: In Zurich, the daily use of public transport was not associated with an additional risk of being diagnosed with Covid-19 among the young population of HCWs, not even during the peak of a pandemic wave. Other factors are more relevant

Suppression of the ferromagnetic state in LaCoO3 films by rhombohedral distortion

Epitaxially strained LaCoO3 (LCO) thin films were grown with different film thickness, t, on (001) oriented (LaAlO3)0.3(SrAl0.5Ta0.5O3)0.7 (LSAT) substrates. After initial pseudomorphic growth the films start to relieve their strain partly by the formation of periodic nano-twins with twin planes predominantly along the direction. Nano-twinning occurs already at the initial stage of growth, albeit in a more moderate way. Pseudomorphic grains, on the other hand, still grow up to a thickness of at least several tenths of nanometers. The twinning is attributed to the symmetry lowering of the epitaxially strained pseudo-tetragonal structure towards the relaxed rhombohedral structure of bulk LCO. However, the unit-cell volume of the pseudo-tetragonal structure is found to be nearly constant over a very large range of t. Only films with t > 130 nm show a significant relaxation of the lattice parameters towards values comparable to those of bulk LCO.Comment: 31 pages, 10 figure

Epitaxial Growth of Thin Films -- a Statistical Mechanical Model

A theoretical framework is developed to describe experiments on the structure of epitaxial thin films, particularly niobium on sapphire. We extend the hypothesis of dynamical scaling to apply to the structure of thin films from its conventional application to simple surfaces. We then present a phenomenological continuum theory that provides a good description of the observed scattering and the measured exponents. Finally the results of experiment and theory are compared.Comment: 10 pages, 3 figures, minor revisions. accepted for publication in J Phys Condense Matte

Vasoactive intestinal polypeptide mediates circadian rhythms in Mammalian olfactory bulb and olfaction

Accumulating evidence suggests that the olfactory bulbs (OBs) function as an independent circadian system regulating daily rhythms in olfactory performance. However, the cells and signals in the olfactory system that generate and coordinate these circadian rhythms are unknown. Using real-time imaging of gene expression, we found that the isolated olfactory epithelium and OB, but not the piriform cortex, express similar, sustained circadian rhythms in PERIOD2 (PER2). In vivo, PER2 expression in the OB of mice is circadian, approximately doubling with a peak around subjective dusk. Furthermore, mice exhibit circadian rhythms in odor detection performance with a peak at approximately subjective dusk. We also found that circadian rhythms in gene expression and odor detection performance require vasoactive intestinal polypeptide (VIP) or its receptor VPAC2R. VIP is expressed, in a circadian manner, in interneurons in the external plexiform and periglomerular layers, whereas VPAC2R is expressed in mitral and external tufted cells in the OB. Together, these results indicate that VIP signaling modulates the output from the OB to maintain circadian rhythms in the mammalian olfactory system.Fil: Kang Miller, Jae Eun. Washington University in St. Louis; Estados UnidosFil: Granados Fuentes, Daniel. Washington University in St. Louis; Estados UnidosFil: Wang, Thomas. Washington University in St. Louis; Estados UnidosFil: Marpegan, Luciano. Washington University in St. Louis; Estados Unidos. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Holy, Timothy E.. Washington University in St. Louis; Estados UnidosFil: Herzog, Erik D.. Washington University in St. Louis; Estados Unido