The left ventral premotor cortex is involved in hand shaping for intransitive gestures: evidence from a two-person imitation experiment

The ventral premotor cortex (PMv) is involved in grasping and object manipulation, while the dorsal premotor cortex (PMd) has been suggested to play a role in reaching and action selection. These areas have also been associated with action imitation, but their relative roles in different types of action imitation are unclear. We examined the role of the left PMv and PMd in meaningful and meaningless action imitation by using repetitive transcranial magnetic stimulation (rTMS). Participants imitated meaningful and meaningless actions performed by a confederate actor while both individuals were motion-tracked. rTMS was applied over the left PMv, left PMd or a vertex control site during action observation or imitation. Digit velocity was significantly greater following stimulation over the PMv during imitation compared with stimulation over the PMv during observation, regardless of action meaning. Similar effects were not observed over the PMd or vertex. In addition, stimulation over the PMv increased finger movement speed in a (non-imitative) finger–thumb opposition task. We suggest that claims regarding the role of the PMv in object-directed hand shaping may stem from the prevalence of object-directed designs in motor control research. Our results indicate that the PMv may have a broader role in ‘target-directed’ hand shaping, whereby different areas of the hand are considered targets to act upon during intransitive gesturing

Repetitive Transcranial Magnetic Stimulation Over the Left Posterior Middle Temporal Gyrus Reduces Wrist Velocity During Emblematic Hand Gesture Imitation

Results from neuropsychological studies, and neuroimaging and behavioural experiments with healthy individuals, suggest that the imitation of meaningful and meaningless actions may be reliant on different processing routes. The left posterior middle temporal gyrus (pMTG) is one area that might be important for the recognition and imitation of meaningful actions. We studied the role of the left pMTG in imitation using repetitive transcranial magnetic stimulation (rTMS) and two-person motion-tracking. Participants imitated meaningless and emblematic meaningful hand and finger gestures performed by a confederate actor whilst both individuals were motion-tracked. rTMS was applied during action observation (before imitation) over the left pMTG or a vertex control site. Since meaningless action imitation has been previously associated with a greater wrist velocity and longer correction period at the end of the movement, we hypothesised that stimulation over the left pMTG would increase wrist velocity and extend the correction period of meaningful actions (i.e., due to interference with action recognition). We also hypothesised that imitator accuracy (actor-imitator correspondence) would be reduced following stimulation over the left pMTG. Contrary to our hypothesis, we found that stimulation over the pMTG, but not the vertex, during action observation reduced wrist velocity when participants later imitated meaningful, but not meaningless, hand gestures. These results provide causal evidence for a role of the left pMTG in the imitation of meaningful gestures, and may also be in keeping with proposals that left posterior temporal regions play a role in the production of postural components of gesture

A framework for live host-based Bitcoin wallet forensics and triage

Organised crime and cybercriminals use Bitcoin, a popular cryptocurrency, to launder money and move it across borders with impunity. The UK and other countries have legislation to recover the proceeds of crime from criminals. Recent UK case law has recognised cryptocurrency assets as property that can be seized and realised under the Proceeds of Crime Act (POCA). To seize a cryptocurrency asset generally requires access to the private key. Anecdotal evidence suggests that if cryptocurrency is not seized quickly after enforcement action has taken place, it will be transferred to other wallets making it difficult to seize at a future time. We investigate how Bitcoin could be seized from an Electrum or Ledger hardware wallet, during a law enforcement search, using live forensic techniques and a dictionary attack.We conduct a literature review examining the state-of-the-art in Bitcoin application forensics and Bitcoin wallet attacks. Concluding, that there is a gap in research on Bitcoin wallet security and that a significant proportion of the available literature comes from a small group of academics working with industry and law enforcement (Volety et al. 2019; Van Der Horst et al., 2017; Zollner et al., 2019). We then forensically examine the Electrum software wallet and the Ledger Nano S hardware wallet, to establish what artefacts can be recovered to assist in the recovery of Bitcoin from the wallets. Our main contribution is a proposed framework for Bitcoin forensic triage, a collection tool to recover Bitcoin artefacts and identifiers, and two proof of concept dictionary-attack tools written in Python and OpenCL.We then evaluate these tools to establish if an attack is practicable using a low-cost cluster of public cloud-based Graphics Processing Unit (GPU) instances. During our investigation, we find a weakness in Electrum's storage of encrypted private keys in RAM. We leverage this to make around 2.4 trillion password guesses. We also demonstrate that we can conduct 16.6 billion guesses against a password protected Ledger seed phrase

A kinematic examination of dual-route processing for action imitation

The dual-route model of imitation suggests that meaningful and meaningless actions are processed through either an indirect or direct route, respectively. Evidence indicates that the direct route is more cognitively demanding, since it relies on mapping visuospatial properties of the observed action on to a performed one. These cognitive demands might negatively influence reaction time and accuracy for actions performed following a meaningless action under time constraints. However, how meaningful and meaningless action imitation processing is reflected in movement kinematics is not yet clear. We wanted to confirm whether meaningless action performance incurs a reaction time cost, whether the cost is reflected in kinematics, and, more generally, to examine kinematic markers of emblematic meaningful and meaningless action imitation. We examined participants’ reaction time and wrist movements when they imitated emblematic meaningful or matched meaningless gestures in either blocks of the same action type, or mixed blocks. Meaningless actions were associated with a greater correction period at the end of the movement, possibly reflecting a strategy designed to ensure accurate completion for less familiar actions under time constraints. Furthermore, in mixed blocks, trials following meaningless actions had a significantly increased reaction time, supporting previous claims that route selection for action imitation may be stimulus-driven. However, there was only convincing evidence for this effect with an interval of ~2948ms, but not ~3573ms or ~2553ms, between movements. Future work motion-tracking the entire hand to assess imitation accuracy, and more closely examining the influence of duration between movements, may help to explain these effects

The left ventral premotor cortex is involved in hand shaping for intransitive gestures: evidence from a two-person imitation experiment

The ventral premotor cortex (PMv) is involved in grasping and object manipulation, whilst the dorsal premotor cortex (PMd) has been suggested to play a role in reaching and action selection. These areas have also been associated with action imitation, but their relative roles in different types of action imitation are unclear. We examined the role of the left PMv and PMd in meaningful and meaningless action imitation by using repetitive transcranial magnetic stimulation (rTMS). Participants imitated meaningful and meaningless actions performed by a confederate actor whilst both individuals were motion-tracked. rTMS was applied over the left PMv, left PMd, or a vertex control site during action observation or imitation. Digit velocity was significantly greater following stimulation over the PMv during imitation compared to stimulation over the PMv during observation, regardless of action meaning. Similar effects were not observed over the PMd or vertex. In addition, stimulation over the PMv increased finger movement speed in a (non-imitative) finger-thumb opposition task. We suggest that claims regarding the role of the PMv in object-directed hand shaping may stem from the prevalence of object-directed designs in motor control research. Our results indicate that the PMv may have a broader role in ‘target-directed’ hand shaping, whereby different areas of the hand are considered targets to act upon during intransitive gesturing

Repetitive transcranial magnetic stimulation over the left posterior middle temporal gyrus reduces wrist velocity during emblematic hand gesture imitation

Results from neuropsychological studies, and neuroimaging and behavioural experiments with healthy individuals, suggest that the imitation of meaningful and meaningless actions may be reliant on different processing routes. The left posterior middle temporal gyrus (pMTG) is one area that might be important for the recognition and imitation of meaningful actions. We studied the role of the left pMTG in imitation using repetitive transcranial magnetic stimulation (rTMS) and two-person motion-tracking. Participants imitated meaningless and emblematic meaningful hand and finger gestures performed by a confederate actor whilst both individuals were motion-tracked. rTMS was applied during action observation (before imitation) over the left pMTG or a vertex control site. Since meaningless action imitation has been previously associated with a greater wrist velocity and longer correction period at the end of the movement, we hypothesised that stimulation over the left pMTG would increase wrist velocity and extend the correction period of meaningful actions (i.e., due to interference with action recognition). We also hypothesised that imitator accuracy (actor-imitator correspondence) would be reduced following stimulation over the left pMTG. Contrary to our hypothesis, we found that stimulation over the pMTG, but not the vertex, during action observation reduced wrist velocity when participants later imitated meaningful, but not meaningless, hand gestures. These results provide causal evidence for a role of the left pMTG in the imitation of meaningful gestures, and may also be in keeping with proposals that left posterior temporal regions play a role in the production of postural components of gesture

An instance of presyncope during magnetic stimulation of the median nerve, and instances of presyncope and syncope during evaluation of resting motor threshold with transcranial magnetic stimulation (TMS)

We report three MS-related events that occurred at the Centre for Integrative Neuroscience and Neurodynamics, University of Reading, Reading, and the School of Psychology, University of Nottingham, Nottingham, both in the UK