6,264 research outputs found
The optimal P3M algorithm for computing electrostatic energies in periodic systems
We optimize Hockney and Eastwood's Particle-Particle Particle-Mesh (P3M)
algorithm to achieve maximal accuracy in the electrostatic energies (instead of
forces) in 3D periodic charged systems. To this end we construct an optimal
influence function that minimizes the RMS errors in the energies. As a
by-product we derive a new real-space cut-off correction term, give a
transparent derivation of the systematic errors in terms of Madelung energies,
and provide an accurate analytical estimate for the RMS error of the energies.
This error estimate is a useful indicator of the accuracy of the computed
energies, and allows an easy and precise determination of the optimal values of
the various parameters in the algorithm (Ewald splitting parameter, mesh size
and charge assignment order).Comment: 31 pages, 3 figure
Microfluidics-based approaches to the isolation of African trypanosomes
African trypanosomes are responsible for significant levels of disease in both humans and animals. The protozoan parasites are free-living flagellates, usually transmitted by arthropod vectors, including the tsetse fly. In the mammalian host they live in the bloodstream and, in the case of human-infectious species, later invade the central nervous system. Diagnosis of the disease requires the positive identification of parasites in the bloodstream. This can be particularly challenging where parasite numbers are low, as is often the case in peripheral blood. Enriching parasites from body fluids is an important part of the diagnostic pathway. As more is learned about the physicochemical properties of trypanosomes, this information can be exploited through use of different microfluidic-based approaches to isolate the parasites from blood or other fluids. Here, we discuss recent advances in the use of microfluidics to separate trypanosomes from blood and to isolate single trypanosomes for analyses including drug screening
Asymptotically exact mean field theory for the Anderson model including double occupancy
The Anderson impurity model for finite values of the Coulomb repulsion is
studied using a slave boson representation for the empty and doubly occupied
-level. In order to avoid well known problems with a naive mean field theory
for the boson fields, we use the coherent state path integral representation to
first integrate out the double occupancy slave bosons. The resulting effective
action is linearized using {\bf two-time} auxiliary fields. After integration
over the fermionic degrees of freedom one obtains an effective action suitable
for a -expansion. Concerning the constraint the same problem remains as
in the infinite case. For and
exact results for the ground state properties are recovered in the saddle point
approximation. Numerical solutions of the saddle point equations show that even
in the spindegenerate case the results are quite good.Comment: 19, RevTeX, cond-mat/930502
Distinct nature of static and dynamic magnetic stripes in cuprate superconductors
We present detailed neutron scattering studies of the static and dynamic
stripes in an optimally doped high-temperature superconductor,
LaCuO. We find that the dynamic stripes do not disperse towards the
static stripes in the limit of vanishing energy transfer. We conclude that the
dynamic stripes observed in neutron scattering experiments are not the
Goldstone modes associated with the broken symmetry of the simultaneously
observed static stripes, but rather that the signals originate from different
domains in the sample. These domains may be related by structural twinning, or
may be entirely different phases, where the static stripes in one phase are
pinned versions of the dynamic stripes in the other. Our results explain
earlier observations of unusual dispersions in underdoped
LaSrCuO () and LaBaCuO ().
Our findings are relevant for all compounds exhibiting magnetic stripes, and
may thus be a vital part in unveiling the nature of high temperature
superconductivity
Many-body GW calculations of ground-state properties: Quasi-2D electron systems and van der Waals forces
We present GW many-body results for ground-state properties of two simple but very distinct families of inhomogeneous systems in which traditional implementations of density-functional theory (DFT) fail drastically. The GW approach gives notably better results than the well-known random-phase approximation, at a similar computational cost. These results establish GW as a superior alternative to standard DFT schemes without the expensive numerical effort required by quantum Monte Carlo simulations
Band Calculation for Ce-compounds on the basis of Dynamical Mean Field Theory
The band calculation scheme for electron compounds is developed on the
basis of the dynamical mean field theory (DMFT) and the LMTO method. The
auxiliary impurity problem is solved by a method named as NCAv', which
includes the correct exchange process of the virtual
excitation as the vertex correction to the non-crossing approximation (NCA) for
the fluctuation. This method leads to the correct magnitude
of the Kondo temperature, , and makes it possible to carry out
quantitative DMFT calculation including the crystalline field (CF) and the
spin-orbit (SO) splitting of the self-energy. The magnetic excitation spectra
are also calculated to estimate . It is applied to Ce metal and CeSb
at T=300 K as the first step. In Ce metal, the hybridization intensity (HI)
just below the Fermi energy is reduced in the DMFT band. The photo-emission
spectra (PES) have a conspicuous SO side peak, similar to that of experiments.
is estimated to be about 70 K in -Ce, while to be about
1700 K in -Ce. In CeSb, the double-peak-like structure of PES is
reproduced. In addition, which is not so low is obtained because HI
is enhanced just at the Fermi energy in the DMFT band.Comment: 30pages, 18 figure
Regge Calculus in Teleparallel Gravity
In the context of the teleparallel equivalent of general relativity, the
Weitzenbock manifold is considered as the limit of a suitable sequence of
discrete lattices composed of an increasing number of smaller an smaller
simplices, where the interior of each simplex (Delaunay lattice) is assumed to
be flat. The link lengths between any pair of vertices serve as independent
variables, so that torsion turns out to be localized in the two dimensional
hypersurfaces (dislocation triangle, or hinge) of the lattice. Assuming that a
vector undergoes a dislocation in relation to its initial position as it is
parallel transported along the perimeter of the dual lattice (Voronoi polygon),
we obtain the discrete analogue of the teleparallel action, as well as the
corresponding simplicial vacuum field equations.Comment: Latex, 10 pages, 2 eps figures, to appear in Class. Quant. Gra
Magnetic ground state and magnon-phonon interaction in multiferroic h-YMnO
Inelastic neutron scattering has been used to study the magneto-elastic
excitations in the multiferroic manganite hexagonal YMnO. An avoided
crossing is found between magnon and phonon modes close to the Brillouin zone
boundary in the -plane. Neutron polarization analysis reveals that this
mode has mixed magnon-phonon character. An external magnetic field along the
-axis is observed to cause a linear field-induced splitting of one of the
spin wave branches. A theoretical description is performed, using a Heisenberg
model of localized spins, acoustic phonon modes and a magneto-elastic coupling
via the single-ion magnetostriction. The model quantitatively reproduces the
dispersion and intensities of all modes in the full Brillouin zone, describes
the observed magnon-phonon hybridized modes, and quantifies the magneto-elastic
coupling. The combined information, including the field-induced magnon
splitting, allows us to exclude several of the earlier proposed models and
point to the correct magnetic ground state symmetry, and provides an effective
dynamic model relevant for the multiferroic hexagonal manganites.Comment: 12 pages, 10 figure
Highly turbulent solutions of LANS-alpha and their LES potential
We compute solutions of the Lagrangian-Averaged Navier-Stokes alpha-model
(LANS) for significantly higher Reynolds numbers (up to Re 8300) than have
previously been accomplished. This allows sufficient separation of scales to
observe a Navier-Stokes (NS) inertial range followed by a 2nd LANS inertial
range. The analysis of the third-order structure function scaling supports the
predicted l^3 scaling; it corresponds to a k^(-1) scaling of the energy
spectrum. The energy spectrum itself shows a different scaling which goes as
k^1. This latter spectrum is consistent with the absence of stretching in the
sub-filter scales due to the Taylor frozen-in hypothesis employed as a closure
in the derivation of LANS. These two scalings are conjectured to coexist in
different spatial portions of the flow. The l^3 (E(k) k^(-1)) scaling is
subdominant to k^1 in the energy spectrum, but the l^3 scaling is responsible
for the direct energy cascade, as no cascade can result from motions with no
internal degrees of freedom. We verify the prediction for the size of the LANS
attractor resulting from this scaling. From this, we give a methodology either
for arriving at grid-independent solutions for LANS, or for obtaining a
formulation of a LES optimal in the context of the alpha models. The fully
converged grid-independent LANS may not be the best approximation to a direct
numerical simulation of the NS equations since the minimum error is a balance
between truncation errors and the approximation error due to using LANS instead
of the primitive equations. Furthermore, the small-scale behavior of LANS
contributes to a reduction of flux at constant energy, leading to a shallower
energy spectrum for large alpha. These small-scale features, do not preclude
LANS to reproduce correctly the intermittency properties of high Re flow.Comment: 37 pages, 17 figure
Wild-Type Drosophila melanogaster as a Model Host to Analyze Nitrogen Source Dependent Virulence of Candida albicans
The fungal pathogen Candida albicans is a common cause of opportunistic infections in humans. We report that wild-type Drosophila melanogaster (OrR) flies are susceptible to virulent C. albicans infections and have established experimental conditions that enable OrR flies to serve as model hosts for studying C. albicans virulence. After injection into the thorax, wild-type C. albicans cells disseminate and invade tissues throughout the fly, leading to lethality. Similar to results obtained monitoring systemic infections in mice, well-characterized cph1Δ efg1Δ and csh3Δ fungal mutants exhibit attenuated virulence in flies. Using the OrR fly host model, we assessed the virulence of C. albicans strains individually lacking functional components of the SPS sensing pathway. In response to extracellular amino acids, the plasma membrane localized SPS-sensor (Ssy1, Ptr3, and Ssy5) activates two transcription factors (Stp1 and Stp2) to differentially control two distinct modes of nitrogen acquisition (host protein catabolism and amino acid uptake, respectively). Our results indicate that a functional SPS-sensor and Stp1 controlled genes required for host protein catabolism and utilization, including the major secreted aspartyl protease SAP2, are required to establish virulent infections. By contrast, Stp2, which activates genes required for amino acid uptake, is dispensable for virulence. These results indicate that nutrient availability within infected hosts directly influences C. albicans virulence
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