Custom Application Cost Survey in Kansas

Crop Production/Industries,

A question of commitment – improving practitioner responses to domestic and sexual violence, problematic substance use and mental ill-health

Purpose – AVA (Against Violence & Abuse) is funded by the Department of Health to deliver the Stella Project Mental Health Initiative. This project aims to develop and implement models of good practice for responding to survivors and perpetrators of abuse who also have a dual diagnosis. Marking the project's halfway point, this article aims to review what is already understood to be best practice in this area, to present the initial learning from the project evaluation, and to consider the most effective ways of promoting and enabling behaviour change among practitioners. Design/methodology/approach – The research design for the evaluation is a mixed methods evaluation, drawing on both prospective and retrospective research techniques. The design was developed within an action research framework. Findings – In line with other research, levels of routine enquiry or enquiry about experiences of violence were low amongst staff from all organisations participating in the project. In comparison staff seem somewhat more likely to enquire about substance misuse and mental health issues. Wide variation in attendance at training was found with a complex relationship between training and confidence emerging. Originality/value – This paper adds to the growing evidence base to suggest that a lot more training, organisational support and research is needed to ensure that professionals who have contact with women who have experienced abuse, have mental health or substance use problems are asking their clients about all three issues, making appropriate referrals and ensuring victims with complex needs having access to protection and support

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Farm Management,

Pasture Leasing Arrangements in Kansas

Farm Management,

A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome

DNA topoisomerases are required to resolve DNA topological stress. Despite this essential role, abortive topoisomerase activity generates aberrant protein-linked DNA breaks, jeopardising genome stability. Here, to understand the genomic distribution and mechanisms underpinning topoisomerase-induced DNA breaks, we map Top2 DNA cleavage with strand-specific nucleotide resolution across the S. cerevisiae and human genomes—and use the meiotic Spo11 protein to validate the broad applicability of this method to explore the role of diverse topoisomerase family members. Our data characterises Mre11-dependent repair in yeast and defines two strikingly different fractions of Top2 activity in humans: tightly localised CTCF-proximal, and broadly distributed transcription-proximal, the latter correlated with gene length and expression. Moreover, single nucleotide accuracy reveals the influence primary DNA sequence has upon Top2 cleavage—distinguishing sites likely to form canonical DNA double-strand breaks (DSBs) from those predisposed to form strand-biased DNA single-strand breaks (SSBs) induced by etoposide (VP16) in vivo

Factor demand linkages, technology shocks, and the business cycle

This paper argues that factor demand linkages can be important for the transmission of both sectoral and aggregate shocks. We show this using a panel of highly disaggregated manufacturing sectors together with sectoral structural VARs. When sectoral interactions are explicitly accounted for, a contemporaneous technology shock to all manufacturing sectors implies a positive response in both output and hours at the aggregate level. Otherwise there is a negative correlation, as in much of the existing literature. Furthermore, we find that technology shocks are important drivers of the business cycle

Effects of Episodic Copper Exposures on Population Fitness

2008 S.C. Water Resources Conference - Addressing Water Challenges Facing the State and Regio

Spectroscopy of z ~ 7 candidate galaxies: using Lyman α to constrain the neutral fraction of hydrogen in the high-redshift universe

Following our previous spectroscopic observations of z > 7 galaxies with Gemini/Gemini Near Infra-Red Spectrograph (GNIRS) and Very Large Telescope (VLT)/XSHOOTER, which targeted a total of eight objects, we present here our results from a deeper and larger VLT/FOcal Reducer and Spectrograph (FORS2) spectroscopic sample of Wide Field Camera 3 selected z > 7 candidate galaxies. With our FORS2 setup we cover the 737–1070 nm wavelength range, enabling a search for Lyman α in the redshift range spanning 5.06–7.80. We target 22 z-band dropouts and find no evidence of Lyman α emission, with the exception of a tentative detection (<5σ, which is our adopted criterion for a secure detection) for one object. The upper limits on Lyman α flux and the broad-band magnitudes are used to constrain the rest-frame equivalent widths for this line emission. We analyse our FORS2 observations in combination with our previous GNIRS and XSHOOTER observations, and suggest that a simple model where the fraction of high rest-frame equivalent width emitters follows the trend seen at z = 3-6.5 is inconsistent with our non-detections at z ∼ 7.8 at the 96 per cent confidence level. This may indicate that a significant neutral H I fraction in the intergalactic medium suppresses Lyman α, with an estimated neutral fraction χHI∼0.5, in agreement with other estimates