525 research outputs found
Simulating lattice gauge theory on a quantum computer
The utility of quantum computers for simulating lattice gauge theories is
currently limited by the noisiness of the physical hardware. Various quantum
error mitigation strategies exist to reduce the statistical and systematic
uncertainties in quantum simulations via improved algorithms and analysis
strategies. We perform quantum simulations of gauge
theory with matter to study the efficacy and interplay of different error
mitigation methods: readout error mitigation, randomized compiling, rescaling,
and dynamical decoupling. We compute Minkowski correlation functions in this
confining gauge theory and extract the mass of the lightest spin-1 state from
fits to their time dependence. Quantum error mitigation extends the range of
times over which our correlation function calculations are accurate by a factor
of six and is therefore essential for obtaining reliable masses.Comment: 20 Pages, 18 Figure
Lymphatic vessels help mend broken hearts
Experiments on zebrafish show that the regeneration of the heart after an injury is supported by lymphatic vessels
Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure
BACKGROUND: Glaucoma is a blinding disease usually associated with high intraocular pressure (IOP). In some families, abnormal anterior segment development contributes to glaucoma. The genes causing anterior segment dysgenesis and glaucoma in most of these families are not identified and the affected developmental processes are poorly understood. Bone morphogenetic proteins (BMPs) participate in various developmental processes. We tested the importance of Bmp4 gene dosage for ocular development and developmental glaucoma. RESULTS: Bmp4(+/-) mice have anterior segment abnormalities including malformed, absent or blocked trabecular meshwork and Schlemm's canal drainage structures. Mice with severe drainage structure abnormalities, over 80% or more of their angle's extent, have elevated IOP. The penetrance and severity of abnormalities is strongly influenced by genetic background, being most severe on the C57BL/6J background and absent on some other backgrounds. On the C57BL/6J background there is also persistence of the hyaloid vasculature, diminished numbers of inner retinal cells, and absence of the optic nerve. CONCLUSIONS: We demonstrate that heterozygous deficiency of BMP4 results in anterior segment dysgenesis and elevated IOP. The abnormalities are similar to those in human patients with developmental glaucoma. Thus, BMP4 is a strong candidate to contribute to Axenfeld-Rieger anomaly and other developmental conditions associated with human glaucoma. BMP4 also participates in posterior segment development and wild-type levels are usually critical for optic nerve development on the C57BL/6J background. Bmp4(+/-) mice are useful for studying various components of ocular development, and may allow identification of strain specific modifiers affecting a variety of ocular phenotypes
Fish community composition and habitat use in the Eg-Uur River System,
Abstract Mongolian rivers and their fi sh communities have suffered severe impacts from anthropogenic activities. However, the remoteness of some systems has allowed for the conservation of unique fi sh faunas, including robust populations of Hucho taimen. Conservation of H. taimen requires understanding the composition and ecology of other fi shes in the community. Using multiple sampling techniques, direct observation, and existing literature, we assessed the composition, relative abundance, and ecological attributes of fi shes in the Eg-Uur watershed (Selenge basin). We collected 6 of 12 species known in the watershed. Phoxinus cf. phoxinus and Lota lota were the most and least abundant species, respectively. We failed to detect H. taimen, indicating low abundance or unknown habitat requirements for juveniles. We compared the effectiveness of different sampling techniques (with electrofi shing producing the highest species richness), constructed length-weight relationships for four species, and identifi ed ecological attributes (i.e., trophic guild, preferred habitat) for resident fi shes
Fish community composition and habitat use in the Eg-Uur River System,
Abstract Mongolian rivers and their fi sh communities have suffered severe impacts from anthropogenic activities. However, the remoteness of some systems has allowed for the conservation of unique fi sh faunas, including robust populations of Hucho taimen. Conservation of H. taimen requires understanding the composition and ecology of other fi shes in the community. Using multiple sampling techniques, direct observation, and existing literature, we assessed the composition, relative abundance, and ecological attributes of fi shes in the Eg-Uur watershed (Selenge basin). We collected 6 of 12 species known in the watershed. Phoxinus cf. phoxinus and Lota lota were the most and least abundant species, respectively. We failed to detect H. taimen, indicating low abundance or unknown habitat requirements for juveniles. We compared the effectiveness of different sampling techniques (with electrofi shing producing the highest species richness), constructed length-weight relationships for four species, and identifi ed ecological attributes (i.e., trophic guild, preferred habitat) for resident fi shes
The Universe Was Reionized Twice
We show the universe was reionized twice, first at z~15-16 and second at z~6.
Such an outcome appears inevitable, when normalizing to two well determined
observational measurements, namely, the epoch of the final cosmological
reionization at z~6 and the density fluctuations at z~6, which in turn are
tight ly constrained by Lyman alpha forest observations at z~3. These two
observations most importantly fix the product of star formation efficiency and
ionizing photon escape fraction from galaxies at high redshift. To the extent
that the relative star formation efficiencies in gaseous minihalos with H2
cooling and large halos with atomic cooling at high redshift are still unknown,
the primary source for the first reionization could be Pop III stars either in
minihalos or in large halos. We show that gas in minihalos can be cooled
efficiently by H2 molecules and star formation can continue to take place
largely unimpeded throughout the first reionization period, thanks to two new
mechanisms for generating a high X-ray background during the Pop III era, put
forth here. Moreover, an important process for producing a large number of H2
molecules in relic HII regions of Pop III galaxies, first pointed out by
Ricotti, Gnedin, & Shull, is quantified here. It is shown that the Lyman-Werner
background may never build up during the Pop III era. The long cosmological
reionization and reheating history is complex. We discuss a wide range of
implications and possible tests for this new reionization picture. In
particular, Thomson scattering optical depth is increased to 0.10 +- 0.03,
compared to 0.027 for the case of only one rapid reionization at z=6. Upcoming
Microwave Anisotropy Probe observation of the polarization of the cosmic
microwave background should be able to distinguish between these two scenarios.Comment: submitted to ApJ, 69 pages, substantial revision made and conclusions
strengthene
The kinetics of lactate production and removal during whole-body exercise
<p>Abstract</p> <p>Background</p> <p>Based on a literature review, the current study aimed to construct mathematical models of lactate production and removal in both muscles and blood during steady state and at varying intensities during whole-body exercise. In order to experimentally test the models in dynamic situations, a cross-country skier performed laboratory tests while treadmill roller skiing, from where work rate, aerobic power and blood lactate concentration were measured. A two-compartment simulation model for blood lactate production and removal was constructed.</p> <p>Results</p> <p>The simulated and experimental data differed less than 0.5 mmol/L both during steady state and varying sub-maximal intensities. However, the simulation model for lactate removal after high exercise intensities seems to require further examination.</p> <p>Conclusions</p> <p>Overall, the simulation models of lactate production and removal provide useful insight into the parameters that affect blood lactate response, and specifically how blood lactate concentration during practical training and testing in dynamical situations should be interpreted.</p
Signatures of Topological Defects
We argue that due to various restrictions cosmic strings and monopole-string
networks are not likely to produce the observed flux of ultra-high energy
cosmic rays (UHECR). Among the topological defects studied so far, the most
promising UHECR sources are necklaces and monopolonia. Other viable sources
which are similar to topological defects are relic superheavy particles. All
these sources have an excess of pions (and thus photons) over nucleons at
production. We demonstrate that in the case of necklaces the diffuse proton
flux can be larger than photon flux, due to absorption of the latter on
radiobackground, while monopolonia and relic particles are concentrated in the
Galactic halo, and the photon flux dominates. Another signature of the latter
sources is anisotropy imposed by asymmetric position of the sun in the Galactic
halo. In all cases considered so far, including necklaces, photons must be
present in ultra-high energy radiation observed from topological defects, and
experimental discrimination between photon-induced and proton-induced extensive
air showers can give a clue to the origin of ultra-high energy cosmic rays.Comment: version accepted for publication in Phys. Rev. D. No changes in the
conclusions and in figure
Willing and able: action-state orientation and the relation between procedural justice and employee cooperation
Existing justice theory explains why fair procedures motivate employees to adopt cooperative goals, but it fails to explain how employees strive towards these goals. We study self-regulatory abilities that underlie goal striving; abilities that should thus affect employees’ display of cooperative behavior in response to procedural justice. Building on action control theory, we argue that employees who display effective self-regulatory strategies (action oriented employees) display relatively strong cooperative behavioral responses to fair procedures. A multisource field study and a laboratory experiment support this prediction. A subsequent experiment addresses the process underlying this effect by explicitly showing that action orientation facilitates attainment of the cooperative goals that people adopt in response to fair procedures, thus facilitating the display of actual cooperative behavior. This goal striving approach better integrates research on the relationship between procedural justice and employee cooperation in the self-regulation and the work motivation literature. It also offers organizations a new perspective on making procedural justice effective in stimulating employee cooperation by suggesting factors that help employees reach their adopted goals
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