2,953 research outputs found

    Tortious Toxics

    Get PDF
    In this Article we offer one small idea with potentially large implications. We propose the recognition arid development of a special tort for toxic exposures, where the exposures have not yet led to a physical illness such as cancer. We argue, in brief, that this new tort would, in one simple step, accomplish three things: it would address many of the problems with the courts\u27 current handling of toxic torts; it would consolidate the many overlapping causes of action now pressed in toxic tort cases into one single claim; and it would give expression to the real injury motivating these cases - a dignitary and autonomy-based harm, not a physical one

    Promoting information literacy through a student video contest

    Get PDF
    This presentation discusses the concept of user-generated content and fansourcing/crowdsourcing, using a video contest, to encourage student participation in the area of information literacy and library instruction. The activity can be a strategy to position the library within campus life and offers an opportunity for constructivist learning

    An Evidence-Based Investigation on The Offending Behaviors of Website Defacers

    Get PDF
    The rapid development of the internet has far outpaced our ability to protect the internet. As new technologies have developed, so have new ways to exploit these technologies to use them for criminal purposes. This is extremely true of the core of the internet, websites. While the number of websites both personal and business focused have skyrocketed, so too have the number of cyber-attacks against these sites. These cyber-attacks are known as website defacements and can cause costly losses and damage the reputation of their internet victims. In such an attack the website defacer gains unauthorized access to the website and changes the appearance of the website, rendering it inoperable for extended periods of time. Prior research on website defacers has provided a preliminary understanding of the motivation and attack preferences of website defacers but given the relative newness of this line of research there are many avenues to deepen our understanding beyond description of these brazen cybercriminals. This dissertation addresses two such areas in need of further study by examining the criminal careers of website defacers and how they respond to potential changes in capable guardianship. As our review of the literature shows, over half of the studies in this literature utilize a data source that was shown to be faulty in measuring the motivational factors of website defacement. Thus, this dissertation used detailed data created by tracking the individual offending patterns of website defacers and utilizing open-source intelligence methods to gather information about each defacer’s characteristics in the sample, rather than the previously mentioned data source. This three-paper dissertation contains a scoping review of the website defacement literature, the first of its kind, to reveal the existing scholarly gaps in this field of research. This dissertation’s second paper uses my previously published paper using this data that revealed important findings on the criminal trajectories of website defacers. The dissertation closes with the first study to examine the effect of holidays on website defacement attack frequencies. These papers serve to outline the direction of future research, aid law enforcement agencies, and bolster our understanding of these cybercriminals’ activities

    The Effect of High Maternal Milk Production During Pregnancy on Neonatal Health and Metabolism

    Get PDF
    The efficiency of the dairy industry relies heavily on the production of healthy calves. However, dairy operations experience high rates of calf mortality due to digestive and respiratory issues. One factor that could predispose calves to disease is the effects of maternal programming caused by high maternal milk production during pregnancy. We hypothesized that calves born to high producing dams will exhibit increased oxidative stress as well as increased circulating triglyceride and total cholesterol concentrations. Cows (n = 17) that produced ≥ 14,865 kg of milk during their lactations were classified as high producers. Alternately, cows (n = 18) that produced ≤ 10,069 kg of milk during their lactation were classified as low producers. At parturition, blood samples from the corresponding calves were collected within 24 hrs of birth (n = 5 to 13 per group per gender). Calves born to low and high producing dams will be referred to as LOW and HIGH respectively. Total serum triglycerides (TG) and total cholesterol (TC) were analyzed at the University of Missouri Veterinary Diagnostic Laboratory. Oxidative stress was measured using a plasma protein carbonyl assay (Sigma-Aldrich, St. Louis, MO). Data were analyzed in SAS using maternal milk production as a covariate. Differences were considered statistically significant when P ≤ 0.05 and a tendency when P \u3e 0.05 ≤ 0.10. No effect of maternal milk production by gender was observed for circulating TC concentrations or plasma protein carbonyl concentrations when comparing LOW calves with HIGH calves for the gender by treatment interaction (P ≥ 0.42). However, LOW female calves had greater circulating TG concentrations (34.23 ± 1.65 mg/dL) when compared with LOW male calves (18.24 ± 2.37 mg/dL; P \u3c 0.01), HIGH male (21.98 ± 2.06 mg/dL; P = 0.08) and HIGH female calves (19.57 ± 3.36 mg/dL; P = 0.06). In newborn calves, the small intestine has a vital role in facilitating passive transfer as well as nutrient absorption. If disrupted, this could impact calf health and metabolism. In conclusion, efficiency of TG absorption appears to be gender dependent. Additionally, these data suggest that LOW female calves are absorbing more lipid from colostrum than HIGH female calves which could aid in maintaining energy balance. A future study will evaluate histological changes in the gastrointestinal tract of calf neonates born to HIGH and LOW producing dams to better understand changes to lipid absorption and passive transfer

    Arctic and Antarctic Analogs for Planetary Surface Traverses

    Get PDF
    The proposed paper summarizes the workshop presentations and discusses several of the key findings or lessons including: (1) A recognition that NASA s current approach for long duration planetary surface operations has fundamental differences from any of the operational approaches described by the invited speakers. These approaches drive the crew size and skill mix to accomplish basic objectives and, in turn, drive the logistical pyramid needed to support these operations. NASA will review the operational approaches of the organizations represented to understand the differentiating factors. NASA will then decide if it should alter its current approach to surface exploration. (2) There are potential parallels between key characteristics of the systems used for exploration in these environments, such as heated volume as an analog for pressurized volume or energy usage for various activities. NASA will look at these characteristics to identify which could help with preliminary planning and gather raw data from the presenters to model these characteristics. (3) New technologies are being applied and design approaches are being tailored to take advantage of these technologies on both side. Interactions between these two communities has begun or is expanding to understand how these new technologies are being leveraged: NASA habitation designers are exchanging ideas and approaches with the Antarctic station designers; Antarctic suppor

    The preservation of some East African freshwater fish

    Get PDF
    Quality changes during storage were investigated for several commercially important East African freshwater fish. Lates, Bagrus, Protopterus, Tilapia esculenta and T. nilotica were examined during storage in ice and at ambient temperature (250•C). After 24 hours at ambient temperature Lates and Bagrus were completely spoilt but Protopterus was still edible. In iced storage most fish were acceptable for at least 20 days. Organoleptic examination showed that T. nilotica was acceptable after 22 days storage in ice and that gutting was only marginally beneficial. Changes in physical appearance, which could form the basis of a fish inspection system, were recorded during storage. Possible chemical quality control indices were also investigated. It was found that total volatile bases and hypoxanthine are unlikely to be useful quality indices for the species studied with the possible exception of Lates. The bacterial counts of the flesh and skin of T. esculenta and T. niloticus were found to be low (a maximum of 10 organisms per sq cm of skin or per g of flesh) after 22 days storage in ice

    Online Mental Health Information Behaviours of Emerging Adults: A Web Usability and User Experience Study

    Get PDF
    This study aims to employ usability study technologies to learn how emerging adults interact online with mental health information

    Tumor-targeting Salmonella typhimurium A1-R inhibits human prostate cancer experimental bone metastasis in mouse models.

    Get PDF
    Bone metastasis is a frequent occurrence in prostate cancer patients and often is lethal. Zoledronic acid (ZOL) is often used for bone metastasis with limited efficacy. More effective models and treatment methods are required to improve the outcome of prostate cancer patients. In the present study, the effects of tumor-targeting Salmonella typhimurium A1-R were analyzed in vitro and in vivo on prostate cancer cells and experimental bone metastasis. Both ZOL and S. typhimurium A1-R inhibited the growth of PC-3 cells expressing red fluorescent protien in vitro. To investigate the efficacy of S. typhimurium A1-R on prostate cancer experimental bone metastasis, we established models of both early and advanced stage bone metastasis. The mice were treated with ZOL, S. typhimurium A1-R, and combination therapy of both ZOL and S. typhimurium A1-R. ZOL and S. typhimurium A1-R inhibited the growth of solitary bone metastases. S. typhimurium A1-R treatment significantly decreased bone metastasis and delayed the appearance of PC-3 bone metastases of multiple mouse models. Additionally, S. typhimurium A1-R treatment significantly improved the overall survival of the mice with multiple bone metastases. The results of the present study indicate that S. typhimurium A1-R is useful to prevent and inhibit prostate cancer bone metastasis and has potential for future clinical use in the adjuvant setting

    Magnetorotationally driven Supernovae as the origin of early galaxy rr-process elements?

    Full text link
    We examine magnetorotationally driven supernovae as sources of rr-process elements in the early Galaxy. On the basis of thermodynamic histories of tracer particles from a three-dimensional magnetohydrodynamical core-collapse supernova model with approximated neutrino transport, we perform nucleosynthesis calculations with and without considering the effects of neutrino absorption reactions on the electron fraction (YeY_{e}) during post-processing. We find that the peak distribution of YeY_{e} in the ejecta is shifted from ∼0.15\sim0.15 to ∼0.17\sim0.17 and broadened toward higher YeY_{e} due to neutrino absorption. Nevertheless, in both cases the second and third peaks of the solar rr-process element distribution can be well reproduced. The rare progenitor configuration that was used here, characterized by a high rotation rate and a large magnetic field necessary for the formation of bipolar jets, could naturally provide a site for the strong rr-process in agreement with observations of the early galactic chemical evolution.Comment: 5 pages, 4 figure

    An Overview of Uncovered and Suspected Large-Scale Structures behind the Milky Way

    Get PDF
    Various dynamically important extragalactic large-scale structures in the local Universe lie behind the Milky Way. Most of these structures (predicted and unexpected) have only recently been made ``visible'' through dedicated deep surveys at various wavelengths. The wide range of observational searches (optical, near infrared, far infrared, radio and X-ray) for galaxies in the Zone of Avoidance (ZOA) will be reviewed and the uncovered and suspected large-scale structures summarised. Particular emphasis is given to the Great Attractor region where the existence of yet another cluster is suspected (Woudt 1998). Predictions from reconstructions of the density field in the ZOA are discussed and compared with observational evidence. Although no major structures are predicted out to about v < 10000 km/s for which no observational evidence exists, the comparison between reconstructed density fields and the observed galaxy distribution remain important as they allow derivations of the density and biasing parameters.Comment: To appear in PASA 16. Proceedings of workshop "HI in the Local Universe, II", held in Melbourne, Sept. 1998. 9 pages, LaTeX2e, 1 encapsulated PS figur
    • …
    corecore