AFFTC overview of orbiter-reentry flight-test results

The Air Force Flight Test Center (AFFTC) has been participating in the flight testing of the Space Shuttle since 1976. An independent assessment of the reentry and landing capabilities of the Orbiter was conducted with respect to Department of Defense (DOD) missions. This activity is on-going and reports have been published after each flight. AFFTC participation in this conference is not directly related to the DOD assessment activity, however, and the views presented by myself and other AFFTC authors discuss the technical aspects of testing and the technology emanating from these tests

Alessandro Valignano and the Restructuring of the Jesuit Mission in Japan, 1579-1582

When Alessandro Valignano arrived in Japan in 1579, the Society of Jesus had been working in the country for thirty years. However, despite impressive numbers and considerable influence with the feudal lords, the mission was struggling. The few Jesuit workers were exhausted and growing increasingly frustrated by the leadership of Francisco Cabral, who refused to cater to Japanese sensibilities or respect the Japanese people. When Valignano arrived, he saw the harm Cabral was doing and forcibly changed the direction of the mission, pursuing policies of Jesuit accommodation to Japanese culture and respect for the Japanese converts who were training to become priests. These policies were based in respect for Japan’s culture and love for its people. Under three years of Valignano’s leadership the fortunes of the Jesuit mission changed and the Society’s work in Japan began to flourish once again. Indeed, Valignano set the course for the next thirty years of the Japanese mission

A model for a space shuttle safing and failure-detection expert

The safing and failure-detection expert (SAFE) is a prototype for a malfunction detection, diagnosis, and safing system for the atmospheric revitalization subsystem (ARS) in the Space Shuttle orbiter. SAFE, whose knowledge was extracted from expert-provided heuristics and documented procedures, automatically manages all phases of failure handling: detection, diagnosis, testing procedures, and recovery instructions. The SAFE architecture allows it to handle correctly sensor failures and multiple malfunctions. Since SAFE is highly interactive, it was used as a test bed for the evaluation of various advanced human-computer interface (HCI) techniques. The use of such expert systems in the next generation of space vehicles would increase their reliability and autonomy to levels not achievable before

Isomorph-Free Branch and Bound Search for Finite State Controllers

The recent proliferation of smart-phones and other wearable devices has lead to a surge of new mobile applications. Partially observable Markov decision processes provide a natural framework to design applications that continuously make decisions based on noisy sensor measurements. However, given the limited battery life, there is a need to minimize the amount of online computation. This can be achieved by compiling a policy into a finite state controller since there is no need for belief monitoring or online search. In this paper, we propose a new branch and bound technique to search for a good controller. In contrast to many existing algorithms for controllers, our search technique is not subject to local optima. We also show how to reduce the amount of search by avoiding the enumeration of isomorphic controllers and by taking advantage of suitable upper and lower bounds. The approach is demonstrated on several benchmark problems as well as a smart-phone application to assist persons with Alzheimer's to wayfind

Utilizing osteocyte derived factors to enhance cell viability and osteogenic matrix deposition within IPN hydrogels

Many bone defects arising due to traumatic injury, disease, or surgery are unable to regenerate, requiring intervention. More than four million graft procedures are performed each year to treat these defects making bone the second most commonly transplanted tissue worldwide. However, these types of graft suffer from a limited supply, a second surgical site, donor site morbidity, and pain. Due to the unmet clinical need for new materials to promote skeletal repair, this study aimed to produce novel biomimetic materials to enhance stem/stromal cell osteogenesis and bone repair by recapitulating aspects of the biophysical and biochemical cues found within the bone microenvironment. Utilizing a collagen type I-alginate interpenetrating polymer network we fabricated a material which mirrors the mechanical and structural properties of unmineralized bone, consisting of a porous fibrous matrix with a young's modulus of 64 kPa, both of which have been shown to enhance mesenchymal stromal/stem cell (MSC) osteogenesis. Moreover, by combining this material with biochemical paracrine factors released by statically cultured and mechanically stimulated osteocytes, we further mirrored the biochemical environment of the bone niche, enhancing stromal/stem cell viability, differentiation, and matrix deposition. Therefore, this biomimetic material represents a novel approach to promote skeletal repair