APPROACHES TO MEASURING CONSUMER BENEFITS FROM FOOD SAFETY

Food safety, consumer benefits, cost/benefit analysis, Food Consumption/Nutrition/Food Safety, Food Security and Poverty,

Assessing residence times of hyporheic ground water in two alluvial flood plains of the Southern Alps using water temperature and tracers

International audienceWater temperature can be used as a tracer for the interaction between river water and groundwater, interpreting time shifts in temperature signals as retarded travel times. The water temperature fluctuates on different time scales, the most pronounced of which are the seasonal and diurnal ones. While seasonal fluctuations can be found in any type of shallow groundwater, high-frequency components are more typical for freshly infiltrated river water, or hyporheic groundwater, and are thus better suited for evaluating the travel time of the youngest groundwater component in alluvial aquifer systems. We present temperature time series collected at two sites in the alpine floodplain aquifers of the Brenno river in Southern Switzerland. At the first site, we determine apparent travel times of temperature for both the seasonal and high-frequency components of the temperature signals in several wells. The seasonal signal appears to travel more slowly, indicating a mixture of older and younger groundwater components, which is confirmed by sulphate measurements. The travel times of the high-frequency component qualitatively agree with the groundwater age derived from radon concentrations, which exclusively reflects young water components. Directly after minor floods, the amplitude of temperature fluctuations in an observation well nearby the river is the highest. Within a week, the riverbed is being clogged, leading to stronger attenuation of the temperature fluctuations in the observation well. At the second site, very fast infiltration to depths of 1.9 m under the riverbed could be inferred from the time shift of the diurnal temperature signal

Assessing hyporheic zone dynamics in two alluvial flood plains of the Southern Alps using water temperature and tracers

International audienceWater temperature can be used as a tracer for the interaction between river water and groundwater, interpreting time shifts in temperature signals as retarded travel times. The water temperature fluctuates on different time scales, the most pronounced of which are the seasonal and diurnal ones. While seasonal fluctuations can be found in any type of shallow groundwater, high-frequency components are more typical for freshly infiltrated river water, or hyporheic groundwater, and are thus better suited for evaluating the travel time of the youngest groundwater component in alluvial aquifer systems. We present temperature time series collected at two sites in the alpine floodplain aquifers of the river Brenno in Southern Switzerland. At the first site, we determine apparent travel times of temperature for both the seasonal and high-frequency components of the temperature signals in several wells. The seasonal signal appears to travel more slowly, indicating a mixture of older and younger groundwater components, which is confirmed by sulphate measurements. The travel times of the high-frequency component qualitatively agree with the groundwater age derived from radon concentrations, which exclusively reflects young water components. Directly after minor floods, the amplitude of temperature fluctuations in an observation well nearby the river is the highest. Within a week, the riverbed is being clogged, leading to stronger attenuation of the temperature fluctuations in the observation well. At the second site, very fast infiltration to depths of 1.9m under the riverbed could be inferred from the time shift of the diurnal temperature signal

Untersuchung der Flusswasserinfiltration in voralpinen Schottern mittels Zeitreihenanalyse

Kurzfassung: Grundwasserfassungen in der Nähe von Flüssen können durch die Infiltration von Flusswasser beeinflusst werden. Aus Sicht des Trinkwasserschutzes interessiert vor allem, welcher Anteil des geförderten Wassers aus dem Fluss stammt und wie lange das Flussinfiltrat im Grundwasserleiter verbleibt, bevor es gefördert wird. Hierzu können Markierversuche durchgeführt werden, die jedoch bei größeren Flüssen mit einem erheblichen Stoffeintrag verbunden sind. Als Alternative zu Markierversuchen stellen wir Methoden vor, um aus Zeitreihen der elektrischen Leitfähigkeit und der Temperatur quantitative Aussagen zu Mischungsverhältnissen und Aufenthaltszeiten abzuleiten. Wir empfehlen ein mehrstufiges Vorgehen bestehend aus: (1) einer qualitativen Analyse, (2) der spektralen Ermittlung des saisonalen Temperatur- und Leitfähigkeitsverlaufs, (3) einer Kreuzkorrelationsanalyse und (4) der nicht-parametrischen Dekonvolution der Zeitreihen. Wir wenden diese Methoden an drei Standorten im Grundwasserstrom des Thurtales im schweizerischen Mittelland an. An Standorten ohne gute Flussanbindung oder mit exfiltrierenden Verhältnissen können die aufwändigen Zeitreihenanalysen nicht angewendet werden, die Messreihen zeigen jedoch die entsprechenden Verhältnisse an. An Standorten mit dauerhafter Flussinfiltration kann aus den Zeitreihen die Durchbruchskurve eines Markierversuches rekonstruiert werden, ohne einen künstlichen Markierstoff in den Fluss geben zu müsse

A complementary method for detecting qi vacuity

<p>Abstract</p> <p>Background</p> <p>Qi vacuity (QV) is defined by traditional Chinese medicine as a loss of energy in the human body. An objective method for detecting QV was not available until recently, however. The automatic reflective diagnosis system (ARDK) is a device that detects human bioenergy through measuring skin conductance at 24 special acupoints on the wrists and ankles.</p> <p>Methods</p> <p>This study used the ARDK to measure skin conductance on 193 patients with QV and 89 sex- and age-matched healthy controls to investigate whether the device is useful in detecting QV. Patients diagnosed with QV have three or more of five symptoms or signs; symptom severity is measured on 5 levels and scored from 0 to 4 points. We compared the difference in the mean ARDK values between patients with QV and healthy controls, and further used linear regression analysis to investigate the correlation between the mean ARDK values and QV scores in patients diagnosed with QV.</p> <p>Results</p> <p>The mean ARDK values in patients with QV (30.2 ± 16.8 μA) are significantly lower than those of healthy controls (37.7 ± 10.8 μA; <it>P </it>< 0.001). A negative correlation was found between the mean ARDK values and QV scores (<it>r </it>coefficient = -0.61; <it>P </it>< 0.001). After adjusting for age, the decreased mean ARDK values in patients with QV showed a significant correlation with the QV scores.</p> <p>Conclusion</p> <p>These results suggest that the mean ARDK values reflect the severity of QV in patients diagnosed with the disorder. They also suggest that the bioenergy level of the human body can be measured by skin conductance. ARDK is a safe and effective complementary method for detecting and diagnosing QV.</p

Clinical profile of parkinsonism and Parkinson's disease in Lagos, Southwestern Nigeria

<p>Abstract</p> <p>Background</p> <p>Current data on the pattern of parkinsonism and Parkinson's disease in Nigerians are sparse.</p> <p>This database was designed to document the clinical profile of PD in Nigerians, and compare this to prior observations.</p> <p>Methods</p> <p>A database of patients presenting to the Neurology out-patients clinic of the Lagos University Teaching Hospital was established in October 1996. Demographic and clinical data at presentation (disease stage using Hoehn and Yahr scale; 'off' state severity on the Unified Parkinson's disease Rating Scale) were documented for patients diagnosed with parkinsonism between October 1996 and December 2006. Cases were classified as Parkinson's disease or secondary parkinsonism (in the presence of criteria suggestive of a secondary aetiology).</p> <p>Results</p> <p>The hospital frequency of parkinsonism (over a 2-year period, and relative to other neurologic disorders) was 1.47% (i.e. 20/1360). Of the 124 patients with parkinsonism, 98 (79.0%) had PD, while 26 (21.0%) had secondary parkinsonism. Mean age (SD) at onset of PD (61.5 (10.0) years) was slightly higher than for secondary parkinsonism (57.5 (14.0) years) (P = 0.10). There was a male preponderance in PD (3.3 to 1) and secondary parkinsonism (2.7 to 1), while a positive family history of parkinsonism was present in only 1.02% (1/98) of PD. There was a modestly significant difference in age at onset (SD) of PD in men (60.3 (10.4)) compared to women (65.2 (7.9)) (T = 2.08; P = 0.04). The frequency of young onset PD (≤ 50 years) was 16.3% (16/98). The mean time interval from onset of motor symptoms to diagnosis of PD was 24.6 ± 26.1 months with majority presenting at a median 12 months from onset. On the H&Y scale, severity of PD at presentation was a median 2.0 (range 1 to 4). PD disease subtype was tremor-dominant in 31 (31.6%), mixed 54 (55.1%) and akinetic-rigid 14 (14.3%). Hypertension was present as a co-morbidity in 20 (20.4%), and diabetes in 6 (6.12%).</p> <p>Conclusions</p> <p>The clinical profile of PD in Nigerians is similar to that in other populations, but is characterized by delayed presentation as has been reported in other developing countries. Young-onset disease occurs but may be less commonly encountered, and frequency of a positive family history is lower than in western populations.</p

In Vivo Tracking of Human Neural Stem Cells with 19F Magnetic Resonance Imaging

(c)The Author

Cerebral activations related to ballistic, stepwise interrupted and gradually modulated movements in parkinson patients

Patients with Parkinson's disease (PD) experience impaired initiation and inhibition of movements such as difficulty to start/stop walking. At single-joint level this is accompanied by reduced inhibition of antagonist muscle activity. While normal basal ganglia (BG) contributions to motor control include selecting appropriate muscles by inhibiting others, it is unclear how PD-related changes in BG function cause impaired movement initiation and inhibition at single-joint level. To further elucidate these changes we studied 4 right-hand movement tasks with fMRI, by dissociating activations related to abrupt movement initiation, inhibition and gradual movement modulation. Initiation and inhibition were inferred from ballistic and stepwise interrupted movement, respectively, while smooth wrist circumduction enabled the assessment of gradually modulated movement. Task-related activations were compared between PD patients (N = 12) and healthy subjects (N = 18). In healthy subjects, movement initiation was characterized by antero-ventral striatum, substantia nigra (SN) and premotor activations while inhibition was dominated by subthalamic nucleus (STN) and pallidal activations, in line with the known role of these areas in simple movement. Gradual movement mainly involved antero-dorsal putamen and pallidum. Compared to healthy subjects, patients showed reduced striatal/SN and increased pallidal activation for initiation, whereas for inhibition STN activation was reduced and striatal-thalamo-cortical activation increased. For gradual movement patients showed reduced pallidal and increased thalamo-cortical activation. We conclude that PD-related changes during movement initiation fit the (rather static) model of alterations in direct and indirect BG pathways. Reduced STN activation and regional cortical increased activation in PD during inhibition and gradual movement modulation are better explained by a dynamic model that also takes into account enhanced responsiveness to external stimuli in this disease and the effects of hyper-fluctuating cortical inputs to the striatum and STN in particular

Commissioning of the vacuum system of the KATRIN Main Spectrometer

The KATRIN experiment will probe the neutrino mass by measuring the beta-electron energy spectrum near the endpoint of tritium beta-decay. An integral energy analysis will be performed by an electro-static spectrometer (Main Spectrometer), an ultra-high vacuum vessel with a length of 23.2 m, a volume of 1240 m^3, and a complex inner electrode system with about 120000 individual parts. The strong magnetic field that guides the beta-electrons is provided by super-conducting solenoids at both ends of the spectrometer. Its influence on turbo-molecular pumps and vacuum gauges had to be considered. A system consisting of 6 turbo-molecular pumps and 3 km of non-evaporable getter strips has been deployed and was tested during the commissioning of the spectrometer. In this paper the configuration, the commissioning with bake-out at 300{\deg}C, and the performance of this system are presented in detail. The vacuum system has to maintain a pressure in the 10^{-11} mbar range. It is demonstrated that the performance of the system is already close to these stringent functional requirements for the KATRIN experiment, which will start at the end of 2016.Comment: submitted for publication in JINST, 39 pages, 15 figure