Towards Learning ‘Self’ and Emotional Knowledge in Social and Cultural Human-Agent Interactions

Original article can be found at: http://www.igi-global.com/articles/details.asp?ID=35052 Copyright IGI. Posted by permission of the publisher.This article presents research towards the development of a virtual learning environment (VLE) inhabited by intelligent virtual agents (IVAs) and modeling a scenario of inter-cultural interactions. The ultimate aim of this VLE is to allow users to reflect upon and learn about intercultural communication and collaboration. Rather than predefining the interactions among the virtual agents and scripting the possible interactions afforded by this environment, we pursue a bottomup approach whereby inter-cultural communication emerges from interactions with and among autonomous agents and the user(s). The intelligent virtual agents that are inhabiting this environment are expected to be able to broaden their knowledge about the world and other agents, which may be of different cultural backgrounds, through interactions. This work is part of a collaborative effort within a European research project called eCIRCUS. Specifically, this article focuses on our continuing research concerned with emotional knowledge learning in autobiographic social agents.Peer reviewe

A new framework for consensus for discrete-time directed networks of multi-agents with distributed delays

Copyright @ 2012 Taylor & FrancisIn this article, the distributed consensus problem is considered for discrete-time delayed networks of dynamic agents with fixed topologies, where the networks under investigation are directed and the time-delays involved are distributed time delays including a single or multiple time delay(s) as special cases. By using the invariance principle of delay difference systems, a new unified framework is established to deal with the consensus for the discrete-time delayed multi-agent system. It is shown that the addressed discrete-time network with arbitrary distributed time delays reaches consensus provided that it is strongly connected. A numerical example is presented to illustrate the proposed methods.This work was supported in part by City University of Hong Kong under Grant 7008114, the Royal Society of the UK, the National Natural Science Foundation of China under Grants 60774073 and 61074129, and the Natural Science Foundation of Jiangsu Province of China under Grant BK2010313

Robust variance-constrained H∞ control for stochastic systems with multiplicative noises

This is the post print version of the article. The official published version can be obtained from the link below - Copyright 2007 Elsevier Ltd.In this paper, the robust variance-constrained H∞ control problem is considered for uncertain stochastic systems with multiplicative noises. The norm-bounded parametric uncertainties enter into both the system and output matrices. The purpose of the problem is to design a state feedback controller such that, for all admissible parameter uncertainties, (1) the closed-loop system is exponentially mean-square quadratically stable; (2) the individual steady-state variance satisfies given upper bound constraints; and (3) the prescribed noise attenuation level is guaranteed in an H∞ sense with respect to the additive noise disturbances. A general framework is established to solve the addressed multiobjective problem by using a linear matrix inequality (LMI) approach, where the required stability, the H∞ characterization and variance constraints are all easily enforced. Within such a framework, two additional optimization problems are formulated: one is to optimize the H∞ performance, and the other is to minimize the weighted sum of the system state variances. A numerical example is provided to illustrate the effectiveness of the proposed design algorithm.This work was supported in part by the Engineering and Physical Sciences Research Council (EPSRC) of the UK under Grant GR/S27658/01, the Nuffield Foundation of the UK under Grant NAL/00630/G, and the Alexander von Humboldt Foundation of Germany

Flare Star Observations with a Single-Photon Counting Imaging Detector

At Los Alamos National Laboratory we are developing a new imaging sensor which combines high spatial and high temporal resolution over a large area format, while maintaining single-photon counting sensitivity and substaining a high count rate. The detector is called a microchannel plate with crossed delay line readout, or MCP/CDL. This detector is ideally suited to the observation of weak transient events, such as stellar flares from red dwarf flare stars in our Galaxy. At present we are initiating an experiment with the MCP/CDL detector which will utilize a 30-cm aperture f/7 telescope to characterize U-band, B-band, and U-band emission from such low- luminosity flare stars, and to search for weak optical transients associated with other astrophysical sources

Flare star observations with a single-photon counting imaging detector

At Los Alamos National Laboratory we are developing a new imaging sensor which combines high spatial and high temporal resolution over a large area format, while maintaining single-photon counting sensitivity and substaining a high count rate. The detector is called a microchannel plate with crossed delay line readout, or MCP/CDL. This detector is ideally suited to the observation of weak transient events, such as stellar flares from red dwarf flare stars in our Galaxy. At present we are initiating an experiment with the MCP/CDL detector which will utilize a 30-cm aperture f/7 telescope to characterize U-band, B-band, and U-band emission from such low- luminosity flare stars, and to search for weak optical transients associated with other astrophysical sources

Exhaled nitric oxide measurements with dynamic flow restriction in children aged 4-8 yrs

Fractional exhaled nitric oxide concentration (FENO) depends on exhalation flow; however, children often are unable to perform controlled flow procedures. Therefore, a device was developed for off-line FENO sampling, with dynamic flow restriction (DFR). The authors compared off-line w

Cell–cell Interaction Underlies Formation of Fluid in the Male Reproductive Tract of the Rat

The epithelia lining the epididymides of many species consists of several cell types. We have provided evidence that the basal cells are essential to the integrated functions of the epithelium. Basal cells, but not principal cells, and other cells in the epididymis express TRPC3 and COX-1. We have isolated basal cells from intact rat epididymis using antibody-coated Dynabeads and subjected them to whole-cell patch-clamp measurement of nonselective cation channel activity, a feature of TRPC3 protein, and Fluo-3 fluorescence measurement of intracellular Ca2+ concentration. The results show that a nonselective cation current blockable by La3+ (0.1 mM), Gd3+ (0.1 mM), or SKF96365 (20 μM) could be activated by lysylbradykinin (200 nM). In cells loaded with Fluo-3, addition of lysylbradykinin (100 nM) caused a sustained increase of intracellular Ca2+. This effect was blocked by Gd3+ (0.1 mM) or SKF96365 (20 μM) and was not observed in Fluo-3–loaded principal cells. Stimulation of basal cell/principal cell cocultures with lysylbradykinin (200 nM) evoked in principal cells a current with CFTR-Cl− channel characteristics. Isolated principal cells in the absence of basal cells did not respond to lysylbradykinin but responded to PGE2 (100 nM) with activation of a CFTR-like current. Basal cells, but not principal cells, released prostaglandin E2 when stimulated with lysylbradykinin (100 nM). The release was blocked by SKF96365 (20 μM) and BAPTA-AM (0.05 or 0.1 mM). Confluent cell monolayers harvested from a mixture of disaggregated principal cells and basal cells responded to lysylbradykinin (100 nM) and PGE2 (500 nM) with an increase in electrogenic anion secretion. The former response was dependent on prostaglandin synthesis as piroxicam blocked the response. However, cell cultures obtained from principal cells alone responded to PGE2 but not to bradykinin. These results support the notion that basal cells regulate principal cells through a Ca2+ and COX signaling pathway

Robust H∞ control for a class of nonlinear discrete time-delay stochastic systems with missing measurements

This is the post print version of the article. The official published version can be obtained from the link - Copyright 2009 Elsevier LtdThis paper is concerned with the problem of robust H∞ output feedback control for a class of uncertain discrete-time delayed nonlinear stochastic systems with missing measurements. The parameter uncertainties enter into all the system matrices, the time-varying delay is unknown with given low and upper bounds, the nonlinearities satisfy the sector conditions, and the missing measurements are described by a binary switching sequence that obeys a conditional probability distribution. The problem addressed is the design of an output feedback controller such that, for all admissible uncertainties, the resulting closed-loop system is exponentially stable in the mean square for the zero disturbance input and also achieves a prescribed H∞ performance level. By using the Lyapunov method and stochastic analysis techniques, sufficient conditions are first derived to guarantee the existence of the desired controllers, and then the controller parameters are characterized in terms of linear matrix inequalities (LMIs). A numerical example is exploited to show the usefulness of the results obtained.This paper was not presented at any IFAC meeting. This paper was recommended for publication in revised form by Associate Editor Dragan Nešic under the direction of Editor Hassan K. Khalil. This work was supported in part by the Engineering and Physical Sciences Research Council (EPSRC) of the U.K. under Grant GR/S27658/01, the City University of Hong Kong under Grant 7001992, the Royal Society of the U.K. under an International Joint Project, the Natural Science Foundation of Jiangsu Province of China under Grant BK2007075, the National Natural Science Foundation of China under Grant 60774073, and the Alexander von Humboldt Foundation of Germany

Oseltamivir- and Amantadine-Resistant Influenza Viruses A (H1N1)

Surveillance of amantadine and oseltamivir resistance among influenza viruses was begun in Hong Kong in 2006. In 2008, while both A/Brisbane/59/2007-like and A/Hong Kong/2652/2006-like viruses (H1N1) were cocirculating, we detected amantadine and oseltamivir resistance among A/Hong Kong/2652/2006-like viruses (H1N1), caused by genetic reassortment or spontaneous mutation

The effects of the bacterial interaction with visible-light responsive titania photocatalyst on the bactericidal performance

Bactericidal activity of traditional titanium dioxide (TiO2) photocatalyst is effective only upon irradiation by ultraviolet light, which restricts the potential applications of TiO2 for use in our living environments. Recently carbon-containing TiO2 was found to be photoactive at visible-light illumination that affords the potential to overcome this problem; although, the bactericidal activity of these photocatalysts is relatively lower than conventional disinfectants. Evidenced from scanning electron microscopy and confocal Raman spectral mapping analysis, we found the interaction with bacteria was significantly enhanced in these anatase/rutile mixed-phase carbon-containing TiO2. Bacteria-killing experiments indicate that a significantly higher proportion of all tested pathogens including Staphylococcus aureus, Shigella flexneri and Acinetobacter baumannii, were eliminated by the new nanoparticle with higher bacterial interaction property. These findings suggest the created materials with high bacterial interaction ability might be a useful strategy to improve the antimicrobial activity of visible-light-activated TiO2