Evaluation of MHOST analysis capabilities for a plate element

Results of the evaluation of the static, buckling, and free vibration analyses capabilities of MHOST for the plate elements are presented. Two large scale, general purpose finite element codes (MARC and MSC/NASTRAN) are used to validate MHOST. Comparisons of MHOST results with those from MARC and MSC/NASTRAN show good agreement and indicate that MHOST can be used with confidence to perform the aforementioned analyses using the plate element

Estimating the phylogeny and divergence times of primates using a supermatrix approach

<p>Abstract</p> <p>Background</p> <p>The primates are among the most broadly studied mammalian orders, with the published literature containing extensive analyses of their behavior, physiology, genetics and ecology. The importance of this group in medical and biological research is well appreciated, and explains the numerous molecular phylogenies that have been proposed for most primate families and genera. Composite estimates for the entire order have been infrequently attempted, with the last phylogenetic reconstruction spanning the full range of primate evolutionary relationships having been conducted over a decade ago.</p> <p>Results</p> <p>To estimate the structure and tempo of primate evolutionary history, we employed Bayesian phylogenetic methods to analyze data supermatrices comprising 7 mitochondrial genes (6,138 nucleotides) from 219 species across 67 genera and 3 nuclear genes (2,157 nucleotides) from 26 genera. Many taxa were only partially represented, with an average of 3.95 and 5.43 mitochondrial genes per species and per genus, respectively, and 2.23 nuclear genes per genus. Our analyses of mitochondrial DNA place Tarsiiformes as the sister group of Strepsirrhini. Within Haplorrhini, we find support for the primary divergence of Pitheciidae in Platyrrhini, and our results suggest a sister grouping of African and non-African colobines within Colobinae and of Cercopithecini and Papionini within Cercopthecinae. Date estimates for nodes within each family and genus are presented, with estimates for key splits including: Strepsirrhini-Haplorrhini 64 million years ago (MYA), Lemuriformes-Lorisiformes 52 MYA, Platyrrhini-Catarrhini 43 MYA and Cercopithecoidea-Hominoidea 29 MYA.</p> <p>Conclusion</p> <p>We present an up-to-date, comprehensive estimate of the structure and tempo of primate evolutionary history. Although considerable gaps remain in our knowledge of the primate phylogeny, increased data sampling, particularly from nuclear loci, will be able to provide further resolution.</p

An integrated multiple criteria decision making approach for resource allocation in higher education

Resource allocation is one of the major decision problems arising in higher education. Resources must be allocated optimally in such a way that the performance of universities can be improved. This paper applies an integrated multiple criteria decision making approach to the resource allocation problem. In the approach, the Analytic Hierarchy Process (AHP) is first used to determine the priority or relative importance of proposed projects with respect to the goals of the universities. Then, the Goal Programming (GP) model incorporating the constraints of AHP priority, system, and resource is formulated for selecting the best set of projects without exceeding the limited available resources. The projects include 'hardware' (tangible university's infrastructures), and 'software' (intangible effects that can be beneficial to the university, its members, and its students). In this paper, two commercial packages are used: Expert Choice for determining the AHP priority ranking of the projects, and LINDO for solving the GP model. Copyright © 2007 Inderscience Enterprises Ltd

Gaseous Pollutants Emission from Diesel Vehicles in Hong Kong

The current study presents the detailed investigation of diesel vehicles emissions utilizing chassis dynamometer test in Hong Kong. Gaseous pollutants from diesel vehicle exhaust, including nitrogen oxides (NOx), total hydrocarbon (THC) and carbon monoxide (CO), are chosen to be the targets of this study. These pollutants were monitored real-time during different testing cycles and the data collected were used to calculate the fuel-based emission factor of each pollutant. Results showed that emission standard and driving conditions are the two main factors governing the trend of emission of these pollutants. Outliers observed in these trends are probably caused by the difference in level of maintenance of the vehicles, which is another important factor affecting the emission of pollutants

Rebuild by Design Phase 1 Evaluation Report

Rebuild by Design (RBD) was formally launched on June 20, 2013, to ensure that the rebuilding after Hurricane Sandy incorporated designs that built in resilience. RBD was launched with strong public leadership, philanthropic support and professional interest within the design community. The early enthusiasm for RBD came as much from curiosity about RBD's vision and ambition as from the substantial size of the implementation awards from the Community Development Block Grant Disaster Recovery (CDBG-DR) funds that Congress appropriated to the U.S. Department of Housing and Urban Development for Hurricane Sandy Recovery.As part of its ongoing commitment to learn from the work it supports, the Rockefeller Foundation provided funding for the Urban Institute to evaluate the design competition component of Phase 1 of RBD, including its innovative aspects, partnerships and community engagement

Tl’azt’en Learning Circle: Information Technology, Health and Cultural Preservation

A Community Learning Centre (CLC) is an innovative model of delivering health care and health information based firmly on the idea of community engagement. It has two interrelated components: 1) a community-based facility with Internet-linked computers accessible to all community members; and 2) community developed web-based resources relevant to community defined needs and priorities. This article describes a pilot CLC implementation in a remote British Columbia First Nations community. A CLC supports the acquisition of health information as well as research and technology skills by facilitating access to, and uptake of, relevant resources developed by and for community members

Polo-like kinase is required for Golgi and bilobe biogenesis in Trypanosoma brucei

A bilobed structure marked by TbCentrin2 regulates Golgi duplication in the protozoan parasite Trypanosoma brucei. This structure must itself duplicate during the cell cycle for Golgi inheritance to proceed normally. We show here that duplication of the bilobed structure is dependent on the single polo-like kinase (PLK) homologue in T. brucei (TbPLK). Depletion of TbPLK leads to malformed bilobed structures, which is consistent with an inhibition of duplication and an increase in the number of dispersed Golgi structures with associated endoplasmic reticulum exit sites. These data suggest that the bilobe may act as a scaffold for the controlled assembly of the duplicating Golgi

Negotiating the Boundaries of (In)Visibility: Asian American Men and Asian/ American Masculinity on Screen.

First and foremost an audience reception study, Negotiating the Boundaries of (In)Visibility illustrates the dialogic relationship of racial discourse in the media and Asian American male identity in the United States. It combines in-depth interviews with textual, discursive, and industry analyses. I showcase how economic, political and technological changes in America and the media industry intersect with cultural shifts in narratives and representations. Defining the boundaries of their identity and culture, interviewees discuss the lack of an Asian American narrative in American popular culture. Rather, Asian Americans contend with larger stereotypes of “Asian,” considered to be a loaded term accompanied by a long history of ethnic homogenization and racial and cultural stereotypes. This dissertation locates particular sites of identification—social surroundings, news media, entertainment media—and how narratives of Asian, American, and Asian American are negotiated, contested, or made visible. In remembering news stories from the mid-2000s, interviewees show how diffuse the concept of “Asia” is in forming identities as racial subjects in America. Analyzing news texts and the rhetoric used to describe these news events, I suggest that the anxiety over China’s economic rise and the accompanying resurgence of “yellow peril” discourse perpetuates the homogenizing definition of “Asian American,” and how national discourse about a foreign threat can shape race relations within. These anxieties are countered by the rise of multicultural ensemble casts and Asian American male leads on primetime television shows. This juxtaposition shapes the complicated space in which Asian American men actively resist, negotiate, and accept racial stereotypes and problematic representations. Providing textual analyses of Lost and Heroes, I suggest that the seemingly progressive multiculturalism presented in entertainment texts perpetuates feelings of subordination and marginalization among racial viewers. Finally, I provide a close reading of television shows’ transmedia narratives their treatment of race. In particular, I suggest the ways in which racial difference becomes more visible as texts appeal to more mainstream audiences. In doing so, I begin a discussion of how multi-platform storytelling may offer new opportunities for articulating race and gender beyond television.Ph.D.CommunicationUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/86392/1/helenho_1.pd

An overview of the rare parotid gland cancer

Cancer of the parotid gland is relatively rare, but carries poor prognosis owing to its prevailing distant metastases. In addition to the disease's basic epidemiology and pathology, we review some current discoveries of its tumorigenesis molecular mechanism. Based on published salivary gland cancer clinical trial data, non-surgical antitumor efficacies amongst a range of chemotherapy, radiation, and concurrent therapy regimens are compared. We also present the current development status of novel radiation therapy and targeted therapeutics, focusing on intensity-modulated radiation therapy (IMRT), and epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF) blockages, which are showing promise for improving parotid gland cancer management

Measuring performance of virtual learning environment system in higher education

Purpose – The purpose of this paper is to measure the performance of commercial virtual learning environment (VLE) systems, which helps the decision makers to select the appropriate system for their institutions. Design/methodology/approach – This paper develops an integrated multiple criteria decision making approach, which combines the analytic hierarchy process (AHP) and quality function deployment (QFD), to evaluate and select the best system. The evaluating criteria are derived from the requirements of those who use the system. A case study is provided to demonstrate how the integrated approach works. Findings – The major advantage of the integrated approach is that the evaluating criteria are of interest to the stakeholders. This ensures that the selected system will achieve the requirements and satisfy the stakeholders most. Another advantage is that the approach can guarantee the benchmarking to be consistent and reliable. From the case study, it is proved that the performance of a VLE system being used at the university is the best. Therefore, the university should continue to run the system in order to support and facilitate both teaching and learning. Originality/value – It is believed that there is no study that measures the performance of VLE systems, and thus decision makers may have difficulties in system evaluation and selection for their institutions