5 research outputs found

    Das Phänomen Hoffenheim : eine Analyse von Konzept und Leistungsvoraussetzungen des Modells 1899 Hoffenheim

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    In der vorliegenden Arbeit soll mittels einer Analyse das Konzept von 1899 Hoffenheim beleuchtet und darüber hinaus aufgezeigt werden, welche Leistungsvoraussetzungen eine Mannschaft für das Spiel in der Ersten Bundesliga derzeit mitbringen muss. Zur Darstellung der Zusammenhänge wurde überwiegend die Fachliteratur aus den Bereichen Sportwissenschaft und Sportökonomie verwendet. Eine weitere wichtige Quelle stellte das Online-Archiv der Fachzeitschrift Sponsors dar, da dort aktuelle Themen zeitnah aufgearbeitet sind. Des weiteren stammen viele Berichte aus Archiven renommierter deutscher Zeitungen wie „Der Spiegel“ oder „Die Welt“. Um der Aktualität eines solchen Themas gerecht zu werden, wurden weite Teile der vorliegenden Arbeit auf der Basis von zuverlässigen Internetquellen formuliert. Institutionen wie der DFB nutzen die Möglichkeiten der Digitalisierung und bieten somit wichtige Quellen nicht mehr als Print-Medien, sondern als pdf-Versionen über das Internet an. Diese Dokumente sind im Literaturverzeichnis unter der jeweiligen Institution aufgeführt

    A Comparison of Major Arable Production Systems: An Agronomic, Environmental and Ecological Evaluation

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    One of the primary challenges of our time is develop sustainable farming systems that can feed the world with minimal environmental impact. Some studies argue that organic farming systems are best because these have minimal impact on the environment and are positive for biodiversity. Others argue that no-tillage systems are better because such systems save energy and preserve soil structure and quality. A third group argues that conventional farming systems are best because yield per hectare is highest. However, so far, systematic comparisons of major arable production systems are rare and often it is difficult to compare the advantages and disadvantages of farming systems in a systematic way due to differences in soil/site characteristics and management. Here we present data of the Swiss Farming Systems and Tillage Experiment (FAST), a long term experiment where the main European arable production systems (organic and conventional farming, reduced tillage and no tillage, each system with different cover crop treatments) are being compared using a factorial replicated design. A multidisciplinary team of researchers from various disciplines and organizations analysed this experiment. We show the advantages and disadvantages of the various production systems and present data on plant yield, life cycle analysis, global warming potential, soil quality, plant root microbiomes and above and below ground biodiversity. Our results demonstrate that: i) plant yield was highest in the conventional systems, ii) soil biodiversity and above ground diversity tended to be higher in organic production systems, iii) soil erosion was lowest in the absence of tillage and in organic production systems, iv) the positive effects of cover crops were highest in organic production systems and increased with reduced land use intensity, v) the global warming potential of organic farming systems was lower compared to conventional systems, and vi) root and plant microbiome varied between the farming systems with the occurrence of indicator species that were specific for individual farming practices. In a next step we compared the results of this experiment with observations from a large farmers network (60 fields) in Switzerland (see abstract by Büchi et al.) where organic, conventional and conservation agriculture were compared. The results of our trial (e.g. yield and environmental performance of the different farming systems) were largely in agreement with those observed in the farmers network. Overall, our results indicate that no farming system is best and the choice of the “best” production system depends on economic, ecological and environmental priorities

    Identification of infants with increased type 1 diabetes genetic risk for enrollment into Primary Prevention Trials-GPPAD-02 study design and first results

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    Primary prevention of type 1 diabetes (T1D) requires intervention in genetically at-risk infants. The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) has established a screening program, GPPAD-02, that identifies infants with a genetic high risk of T1D, enrolls these into primary prevention trials, and follows the children for beta-cell autoantibodies and diabetes. Genetic testing is offered either at delivery, together with the regular newborn testing, or at a newborn health care visits before the age of 5 months in regions of Germany (Bavaria, Saxony, Lower Saxony), UK (Oxford), Poland (Warsaw), Belgium (Leuven), and Sweden (Region Skåne). Seven clinical centers will screen around 330 000 infants. Using a genetic score based on 46 T1D susceptibility single-nucleotide polymorphisms (SNPs) or three SNPS and a first-degree family history for T1D, infants with a high (>10%) genetic risk for developing multiple beta-cell autoantibodies by the age of 6 years are identified. Screening from October 2017 to December 2018 was performed in 50 669 infants. The prevalence of high genetic risk for T1D in these infants was 1.1%. Infants with high genetic risk for T1D are followed up and offered to participate in a randomized controlled trial aiming to prevent beta-cell autoimmunity and T1D by tolerance induction with oral insulin. The GPPAD-02 study provides a unique path to primary prevention of beta-cell autoimmunity in the general population. The eventual benefit to the community, if successful, will be a reduction in the number of children developing beta-cell autoimmunity and T1D.status: publishe
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