594 research outputs found
You Can\u27t Have Your Trust and Defeat It Too: Why Mandatory Arbitration Provisions in Trusts Are Enforceable, and Why State Courts Are Getting It Wrong
This note addresses a recent decision by the Texas State Court of Appeals concerning the enforceability of mandatory arbitration provisions found in testamentary instruments, and specifically, inter vivos trusts. After analyzing the legal background of arbitration, the use of contract principles to analyze both arbitration and trust agreements, and statutory enactments making trust arbitration provisions enforceable, this note will discuss the nuanced relationship between contract principles of construction, arbitration agreements, and trust instruments, and specifically the relationship between trust agreements and contracts. In analyzing these relationships, this note will also address the differences between the statute at issue in Rachal v. Reitz and the Arizona arbitration statute at issue in Schoneberger v. Delze, the landmark case addressing the enforceability of trust arbitration provisions. Additionally, the relationship between contract law, trust instruments, and the role of settlors\u27 intent will be briefly discussed. Finally, this note will argue that mandatory arbitration provisions found in valid trust instruments should be enforced when they would effectuate the settlor\u27s unambiguous intent
You Can\u27t Have Your Trust and Defeat It Too: Why Mandatory Arbitration Provisions in Trusts Are Enforceable, and Why State Courts Are Getting It Wrong
This note addresses a recent decision by the Texas State Court of Appeals concerning the enforceability of mandatory arbitration provisions found in testamentary instruments, and specifically, inter vivos trusts. After analyzing the legal background of arbitration, the use of contract principles to analyze both arbitration and trust agreements, and statutory enactments making trust arbitration provisions enforceable, this note will discuss the nuanced relationship between contract principles of construction, arbitration agreements, and trust instruments, and specifically the relationship between trust agreements and contracts. In analyzing these relationships, this note will also address the differences between the statute at issue in Rachal v. Reitz and the Arizona arbitration statute at issue in Schoneberger v. Delze, the landmark case addressing the enforceability of trust arbitration provisions. Additionally, the relationship between contract law, trust instruments, and the role of settlors\u27 intent will be briefly discussed. Finally, this note will argue that mandatory arbitration provisions found in valid trust instruments should be enforced when they would effectuate the settlor\u27s unambiguous intent
Quadratic Scaling Bosonic Path Integral Molecular Dynamics
We present an algorithm for bosonic path integral molecular dynamics
simulations, which reduces the computational complexity with the number of
particles from cubic to quadratic. Path integral molecular dynamics simulations
of large bosonic systems are challenging, since a straightforward
implementation scales exponentially with the number of particles. We recently
developed a recursive algorithm that reduced the computational complexity from
exponential to cubic. It allowed performing the first path integral molecular
dynamics simulations of ~100 bosons, but the cubic scaling hindered
applications to much larger systems. Here, we report an improved algorithm that
scales only quadratically with system size. Simulations with our new method are
orders of magnitude faster, with a speedup that scales as , where and
are the number of beads (imaginary time slices) and particles,
respectively. In practice, this eliminates most of the cost of including
bosonic exchange effects in path integral molecular dynamics simulations. We
use the algorithm to simulate thousands of interacting bosons using path
integral molecular dynamics for the first time, spending days of computation on
simulations that would have otherwise taken decades to complete
Rokhlin Dimension for Flows
This research was supported by GIF Grant 1137/2011, SFB 878 Groups, Geometry and Actions and ERC Grant No. 267079. Part of the research was conducted at the Fields institute during the 2014 thematic program on abstract harmonic analysis, Banach and operator algebras, and at the Mittag–Leffler institute during the 2016 program on Classification of Operator Algebras: Complexity, Rigidity, and Dynamics.Peer reviewedPostprin
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The peripheral blood transcriptome in septic cardiomyopathy: an observational, pilot study.
BACKGROUND:Septic cardiomyopathy (SCM) is common in sepsis and associated with increased morbidity and mortality. Left ventricular global longitudinal strain (LV GLS), measured by speckle tracking echocardiography, allows improved identification of impaired cardiac contractility. The peripheral blood transcriptome may be an important window into SCM pathophysiology. We therefore studied the peripheral blood transcriptome and LV GLS in a prospective cohort of patients with sepsis. RESULTS:In this single-center observational pilot study, we enrolled adult patients (age > 18) with sepsis within 48 h of admission to the ICU. SCM was defined as LV GLS > - 17% based on echocardiograms performed within 72 h of admission. We enrolled 27 patients, 24 of whom had high-quality RNA results; 18 (75%) of 24 had SCM. The group was 50% female and had a median (IQR) age of 59.5 (48.5-67.0) years and admission APACHE II score of 21.0 (16.0-32.3). Forty-six percent had septic shock. After filtering for low-expression and non-coding genes, 15,418 protein coding genes were expressed and 73 had significantly different expression between patients with vs. without SCM. In patients with SCM, 43 genes were upregulated and 30 were downregulated. Pathway analysis identified enrichment in type 1 interferon signaling (adjusted p < 10-5). CONCLUSIONS:In this hypothesis-generating study, SCM was associated with upregulation of genes in the type 1 interferon signaling pathway. Interferons are cytokines that stimulate the innate and adaptive immune response and are implicated in the early proinflammatory and delayed immunosuppression phases of sepsis. While type 1 interferons have not been implicated previously in SCM, interferon therapy (for viral hepatitis and Kaposi sarcoma) has been associated with reversible cardiomyopathy, perhaps suggesting a role for interferon signaling in SCM
The Index of (White) Noises and their Product Systems
(See detailed abstract in the article.) We single out the correct class of
spatial product systems (and the spatial endomorphism semigroups with which the
product systems are associated) that allows the most far reaching analogy in
their classifiaction when compared with Arveson systems. The main differences
are that mere existence of a unit is not it sufficient: The unit must be
CENTRAL. And the tensor product under which the index is additive is not
available for product systems of Hilbert modules. It must be replaced by a new
product that even for Arveson systems need not coincide with the tensor
product
Lung adenocarcinoma presenting as a solitary gingival metastasis: a case report
<p>Abstract</p> <p>Introduction</p> <p>Gingival metastases are very rare and generally occur in disseminated tumors. We report a case of solitary gingival metastasis of lung cancer.</p> <p>Case presentation</p> <p>We report the case of a 74-year-old asymptomatic Caucasian woman affected by a rapidly growing, painless gingival swelling. Histopathologic examination of the excisional biopsy showed metastasis of poorly differentiated thyroid transcription factor 1-positive adenocarcinoma. A total-body computed tomographic scan revealed a tumor of the right lung lower lobe with ipsilateral, mediastinal lymph node swelling. Moreover, bone scintigraphy revealed no bone metastases. No other metastases were found, so we planned a multi-modal therapeutic approach with a curative intent. However, the tumor proved to be intrinsically resistant and highly aggressive.</p> <p>Conclusion</p> <p>The presentation of solitary gingival metastasis is exceptional. In view of its rapid clinical evolution, our case confirms that gingival metastasis is an important prognostic factor. This behavior raises the question whether the poor prognosis for patients with tumors with oral metastases depends on its diffuse spread or on its highly malignant nature.</p
Association of left ventricular longitudinal strain with central venous oxygen saturation and serum lactate in patients with early severe sepsis and septic shock
Syftet med denna studie är att synliggöra pedagogers syn på föräldrasamverkan i förskolan. Vi har även intresserat oss på samverkan mellan pedagogerna och föräldrar med annat modersmål än svenska. Vår studie grundar sig på observationer kring bemötande av föräldrar på förskolan. Vi undersökte hur pedagogerna såg på föräldrasamverkan och hur de arbetar kring samverkan med föräldrar, för att kunna få en bredare syn i vår studie om hur samverkan fungerar på de aktuella förskolorna. Som metod använde vi kvalitativ intervju då detta lämpade sig väl för oss för att vi skulle kunna få en bredare syn om hur samverkan fungerar på de aktuella förskolorna. Intervjuer ger mer exakta svar och det underlättar för oss som intervjuar att ställa följdfrågor. Resultatet visar att samverkan med föräldrar har ökat i förskolan och blivit en stor del av verksamheten. Pedagogerna försöker engagera sig mycket i arbetet med föräldrasamverkan och letar efter möjligheter för att skapa en bra kommunikation med föräldrar som har annat modersmål än svenska. Resultaten visar även att pedagogerna menar att oavsett om föräldrarna behärskar det svenska språket eller inte så anstränger de sig för att visa föräldrarna att de är viktiga i verksamheten
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