627 research outputs found
INDIGENOUS LAND TENURE AND LAND USE IN ALASKA: COMMUNITY IMPACTS OF THE ALASKA NATIVE CLAIMS SETTLEMENT ACT
Through the utilization of qualitative methods such as archival analysis, semi-structured interviewing, comparative and extended case studies, and observation, this paper closely examines two related Alaska Native communities. Our purpose is to document the impact of the Alaska Native Claims Settlement Act of 1971 (ANCSA) on land tenure, land use, and community structure. In all, 41 interviews were conducted, focusing on the following issues: (1) the role of the tribal government in relation to the regional and village corporate structure; (2) the recent changes in traditional land uses; and (3) how group decisions are made regarding land management and distribution of resources. By locating ANCSA within a broader context of economic, political, and cultural globalization that seeks to substitute traditional collective rights in land with individual tenure in a "free market" economy, the findings of this research may carefully and cautiously be applied beyond North America to other indigenous-state struggles regarding control of land and resources.United States. -- [Alaska Native Claims Settlement Act], Indians of North America -- Legal status, laws, etc. -- Alaska, Land tenure -- Law and legislation -- Alaska, Indians of North America -- Alaska -- Claims, Indians of North America -- Land tenure -- Alaska, Indians of North America -- Alaska -- Government relations -- History, Land Economics/Use,
Maneuver Estimation Model for Geostationary Orbit Determination
As an increasing number of geostationary satellites fill a limited number of orbital slots, collocation of satellites leads to a risk of close approach or misidentification. The ability to detect maneuvers made by these satellites using optical observations can help to prevent these problems. Such a model has already been created and tested using data from the Air Force Maui Optical and Supercomputing site. The goal of this research was to create a more robust model which would reduce the amount of data needed to make accurate maneuver estimations. The Clohessy-Wiltshire equations were used to model the relative motion of a geostationary satellite about its intended location, and a nonlinear least squares algorithm was developed to estimate the satellite trajectories
Appendix B: Ohio Attorney General Facial Recognition Task Force Proposal on Monitoring, Auditing, Enforcement and Transparency
Policy controls that govern agency activity generally contain at least two components: (1) a substantive policy; and (2) a governance structure for ensuring implementation of and compliance with that policy. Effective controls require both. This proposal focuses on the second component, the governance structure. Specifically, it addresses routine monitoring, annual audits, enforcement of the AG’s policies that govern the facial recognition system, and public transparency. Established facial recognition policies, including those that the Task Force has looked to as models, recognize the importance of establishing such a governance structure.
We have reviewed existing federal and state policy templates documents in order to identify and integrate best practices. Based on this review, we believe that Ohio’s Facial Recognition Policy should address routine monitoring, periodic audits, enforcement, and public transparency. A policy that successfully integrated each of these elements would reflect best practices and could serve as a model for other states and localities
Strength and Mobility Measures in Division I Female Volleyball Student Athletes Across Different Positions
Shoulder internal and external rotation and hand grip measures are commonly used to evaluate upper extremity mobility and strength in college athletes. However, positional differences and their impact on these scores are rarely considered, therefore further research is needed in sports such as volleyball where information on these potential trends is lacking. PURPOSE: The purpose of this study was to identify possible differences between strength and mobility measures in female volleyball student-athletes whose responsibilities include hitting (predominantly overhead roles) versus those who are primarily passers and diggers (non-overhead roles). METHODS: Thirteen Division I volleyball student-athletes who volunteered to participate in this study were divided into two groups - hitters (H; age = 19.6 ± 1.5 y, height = 180.7 ± 6.7 cm) and passers (P; age = 19.3 ± 1.2 y, height = 172.0 ± 10.0 cm). Players were tested on their shoulder range of motion (ROM) for internal rotation (IR), external rotation (ER), and flexion using a goniometer. Total ROM was identified as a sum of IR and ER. Hand grip strength was measured in the dominant hand using a hand grip dynamometer. All testing was completed by certified healthcare professionals prior to preseason following clearance by the team physician. Descriptive statistics were calculated as mean ± standard deviations. RESULTS: H had higher total ROM than P in both the right arm (158.6 ± 65.8° vs 144.1 ± 65.8°) and left arm (165.0 ± 67.8° vs 155.7 ± 69.7°). H had higher flexion than P in the right, dominant arm (176.9 ± 7.9° vs 171.5 ± 18.7°), but similar flexion in the left, nondominant arm (180.1 ± 5.6° vs 180.7 ± 3.4°). H and P both had higher than average values for shoulder ROM compared to published normative data. Hand grip strength was also higher in H compared to P (31.6 ± 6.2 kg vs 26.1 ± 2.5 kg). CONCLUSIONS: H displayed greater total ROM in both arms, a higher flexion ROM in their dominant arm than P as well as greater strength in their dominant arm. This emphasizes the importance of mobility and strength in their positional demands, and the need for shoulder stability. This information provides strength and conditioning coaches preliminary information on possible foci for training and areas where further research is still needed
Lower Extremity Strength and Mobility in Division I Male Basketball Players Across Vertical Jump Performance
Vertical jump (VJ) performance is a commonly used assessment to measure explosive muscular power in collegiate strength and power athletes such as basketball players. However, research on the relationship between VJ performance and measures of lower extremity (LE) strength and mobility is inconsistent. PURPOSE: The purpose of this study was to analyze hip and ankle strength and mobility measures among collegiate male basketball players by comparing those with higher and lower VJ performance. METHODS: During pre-season screening, ten Division I male basketball players were assessed to determine VJ height by completing a countermovement VJ test. Players were divided into two groups based on VJ performance which were comprised of the top 5 performers (T; 20.8 ± 2.0 years, 186.4 ± 7.4 cm, 79.6 ± 8.6 kg; VJ: 70.4 ± 6.9 cm) and the bottom 5 performers (B; 20.0 ± 1.6 years, 197.4 ± 9.9 cm, 94.2.6 ± 19.7 kg; VJ: 56.9 ± 2.5 cm). Hip range of motion (ROM) was measured with a goniometer, and total hip ROM was calculated as the sum of internal and external rotation for each limb. Ankle dorsiflexion was assessed using a clinometer instrument. Hip abduction (ABD) and adduction (ADD) strength was measured using a dynamometer, and calculated relative to body weight. Players also self-reported LE injuries in the prior 12 months. Descriptive statistics were calculated as mean ± standard deviation. RESULTS: Compared to B, T had lower left leg hip ROM (69.4 ± 6.6° vs 72.6 ± 7.5°). T had higher right leg hip ROM (73.4 ± 5.0° vs 70.0 ± 11.9°) and left/right ankle ROM (36.8 ± 4.1° vs 33.2 ± 3.0° and 35.4 ± 2.4° vs 32.8 ± 4.0°, respectively). T had higher relative right/left leg ABD strength (43.5 ± 6.3 vs 37.5 ± 10.9 % and 37.8 ± 7.1 vs 36.8 ± 11.8 %, respectively), and right/left leg ADD strength (44.0 ± 21.4 vs 40.9 ± 6.1 % and 41.2 ± 10.5 vs 39.5 ± 12.3 %, respectively). However, only 20% of the T group compared to 60% of the B group reported experiencing a recent LE injury. CONCLUSION: Although the T group had higher right leg hip ROM, ankle ROM, and greater hip strength these were just trends, making it difficult to draw any inferences about the association between hip and ankle strength and mobility measures on VJ performance. It is also possible that the greater presence of recent LE injury in the B group may have impacted the findings of this study
Interaction between IRF6 and TGFA Genes Contribute to the Risk of Nonsyndromic Cleft Lip/Palate
Previous evidence from tooth agenesis studies suggested IRF6 and TGFA interact. Since tooth agenesis is commonly found in individuals with cleft lip/palate (CL/P), we used four large cohorts to evaluate if IRF6 and TGFA interaction contributes to CL/P. Markers within and flanking IRF6 and TGFA genes were tested using Taqman or SYBR green chemistries for case-control analyses in 1,000 Brazilian individuals. We looked for evidence of gene-gene interaction between IRF6 and TGFA by testing if markers associated with CL/P were overtransmitted together in the case-control Brazilian dataset and in the additional family datasets. Genotypes for an additional 142 case-parent trios from South America drawn from the Latin American Collaborative Study of Congenital Malformations (ECLAMC), 154 cases from Latvia, and 8,717 individuals from several cohorts were available for replication of tests for interaction. Tgfa and Irf6 expression at critical stages during palatogenesis was analyzed in wild type and Irf6 knockout mice. Markers in and near IRF6 and TGFA were associated with CL/P in the Brazilian cohort (p<10-6). IRF6 was also associated with cleft palate (CP) with impaction of permanent teeth (p<10-6). Statistical evidence of interaction between IRF6 and TGFA was found in all data sets (p = 0.013 for Brazilians; p = 0.046 for ECLAMC; p = 10-6 for Latvians, and p = 0.003 for the 8,717 individuals). Tgfa was not expressed in the palatal tissues of Irf6 knockout mice. IRF6 and TGFA contribute to subsets of CL/P with specific dental anomalies. Moreover, this potential IRF6-TGFA interaction may account for as much as 1% to 10% of CL/P cases. The Irf6-knockout model further supports the evidence of IRF6-TGFA interaction found in humans. © 2012 Letra et al
Intratumoral Gold Nanoparticle-Enhanced CT Imaging: An in Vivo Investigation of Biodistribution and Retention
This study aims to evaluate the in vivo distribution of Gold Nanoparticles (GNPs) at different time points after intratumoral (IT) injection, exploiting their properties as contrast agents for Computed Tomography (CT). GNPs approximately 40 nm in diameter were synthesized with a surface plasmon peak at ~530 nm, capped with Bovine Serum Albumin (BSA) to improve colloidal stability, and characterized with standard methods. CT phantom imaging was performed to quantify X-ray attenuation as a function of GNP concentration and surface functionalization and to determine the appropriate particle dose for in vivo studies. Concentrated GNPs were intratumorally (IT) injected into Lewis Lung Carcinoma (LLC) solid tumors grown on the right flank of 6-week old female C57BL/6 mice. Ten days post-injection, follow up CT imaging was performed to assess the distribution and retention of the particles in the tumor. Using the CT attenuation quantification, images for each timepoint were segmented, and 3D volumes rendered, to conduct biodistribution analyses. The successful retention and permanence of the GNPs into the solid tumor after ten days suggests the significance of GNPs as a potential theranostic agent
Predicting Left Ventricular Assist Device Outcomes Utilizing the Stanford Integrated Psychosocial Assessment for Transplant Measure
Objective: Durable mechanical circulatory support is a proven therapy to extend survival for patients with end-stage heart failure (HF). The International Society for Heart and Lung Transplantation guidelines recommend a detailed psychosocial assessment when selecting candidates for durable mechanical circulatory support. Currently, there are no formally validated psychosocial evaluation tools for left ventricular assist device (LVAD) candidacy. The Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT) uses a multidisciplinary algorithm to evaluate the impact of pre-transplant risk factors on post-transplant outcomes. Emerging literature suggests that the SIPAT might be useful for assessing psychosocial risk factors for LVAD outcomes.
Methods: A total of 268 consecutive patients (median age 66 years, 84.6% male) with terminal HF were evaluated before LVAD implantation with a SIPAT assessment. Key outcomes included readmission and mortality rates at 30 days and two years.
Results: After screening, 234 subjects met the inclusion criteria and were analyzed. The Patient Readiness subscale of the SIPAT was statistically significant in predicting two-year mortality (B = .167, P \u3c .001; Nagelkerke r2 = .106). Scores on the SIPAT did not correlate to 30-day readmission, 30-day mortality, or two-year readmission rates.
Discussion: In this study, only the Patient Readiness score was associated with mortality at two-years post-implantation. This research elucidates the potential longer-term impact of psychosocial factors on LVAD outcomes and the SIPAT’s utility in evaluating LVAD candidacy
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