46 research outputs found

    Opportunity Recognition: Perceptions of Highly Successful Entrpreneurs

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    This study examined  multiple dimensions  of opportunity recognition  (OR) among a group  of exceptionally successful entrepreneurs and a control group of more randomly selected entrepreneurs.  There were few  differences  between the two groups.  Results  indicated that OR stemmed from prior experience, focusing on markets and customers, and responses to specific problems along with several other sources. Furthermore, OR appeared to he a multiple-step process far more frequently than a "eureka" experience. These results support much of the conventional wisdom about OR and indicate that multiple approaches to OR can lead  to success

    Examining the Role of Social Network Size and the Structural Holes

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    This study examines the importance of social network size and structural holes within the network to the entrepreneurial opportunity recognition process

    Entrepreneurial Orientation as the Determinant of Entrepreneurial Marketing Behaviors

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    Although entrepreneurial marketing (EM) behaviors are widely reported, there is little discussion on what determines the level of a firm’s behaviors. This study contributes to the knowledge in the fields of entrepreneurship and entrepreneurial marketing by proposing EO, entrepreneurial orientation, as an antecedent of EM behaviors and arguing that EO acts as a multidimensional construct when affecting EM behaviors. The relationships between EO and EM behaviors are empirically investigated using multi-group confirmatory factor analysis and structural equation modeling techniques. Results from the analyses support the hypothesis that EM behaviors are driven by EO. Firms with a higher level of EO engaged in EM behaviors more than firms with a lower level of EO. At the dimension level, innovativeness, proactiveness, and risk-taking are found to independently affect EM behaviors. With innovativeness having the strongest impact, this study concludes that innovativeness is the leading essence of EM behaviors. The results support a new consensus among entrepreneurship research scholars who suggest a direction toward multidimensional EO.

    Alternative approaches to the legal, institutional and financial aspects of developing an inter-island electrical transmission cable system

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    This study (I) delineates three comprehensive alternative scenarios for the development, financing, construction, ownership, regulation and operation of an inter-island electric energy transmission cable systemDepartment of Planning and Economic Development, State of Hawai

    Phylogenetic Hypotheses for the Monocotyledons Constructed from rbcL Sequence Data

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    DNA sequences for the plastid locus that encodes the large subunit of ribulose 1,5-bisphosphate carboxylase/oxygenase (rbcL) were determined for 18 species of monocotyledons in 15 families. These data were analyzed together with sequences for 60 other monocot species in a total of 52 families by the maximum likelihood method producing one, presumably optimal, topology. An additional 26 species were added (104 total monocot species) and analyzed by the parsimony method with an outgroup of 18 dicot species producing 109 trees of 3,932 steps. The rbcL data show at least moderate support for seven lineages corresponding to the following orders, superorders, or combinations: Arecanae; Asparagales (excluding Hypoxidaceae) plus Iridaceae; Cyclanthanae plus Pandananae; Dioscoreales; Orchidales; Typhales; and Zingiberanae. Six clades corresponding to families or genera are well supported, including: Agavaceae, Asphodelaceae, Bromeliaceae, Hypoxidaceae, Poaceae, and Tradescantia. The two, earliest diverging multispecies clades in our rbcL phylogenies, Alismatanae and Aranae, are only weakly supported, and Bromelianae, Commelinanae, and Lilianae are paraphyletic. In all analyses Acorus calamus is phylogenetically isolated as the sister species to the remaining species of monocotyledons

    Phylogenetics of Seed Plants: An Analysis of Nucleotide Sequences from the Plastid Gene rbcL

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    We present the results of two exploratory parsimony analyses of DNA sequences from 475 and 499 species of seed plants, respectively, representing all major taxonomic groups. The data are exclusively from the chloroplast gene rbcL, which codes for the large subunit of ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO or RuBPCase). We used two different state-transformation assumptions resulting in two sets of cladograms: (i) equal-weighting for the 499-taxon analysis; and (ii) a procedure that differentially weights transversions over transitions within characters and codon positions among characters for the 475-taxon analysis. The degree of congruence between these results and other molecular, as well as morphological, cladistic studies indicates that rbcL sequence variation contains historical evidence appropriate for phylogenetic analysis at this taxonomic level of sampling. Because the topologies presented are necessarily approximate and cannot be evaluated adequately for internal support, these results should be assessed from the perspective of their predictive value and used to direct future studies, both molecular and morphological. In both analyses, the three genera of Gnetales are placed together as the sister group of the flowering plants, and the anomalous aquatic Ceratophyllum (Ceratophyllaceae) is sister to all other flowering plants. Several major lineages identified correspond well with at least some recent taxonomic schemes for angiosperms, particularly those of Dahlgren and Thorne. The basalmost clades within the angiosperms are orders of the apparently polyphyletic subclass Magnoliidae sensu Cronquist. The most conspicuous feature of the topology is that the major division is not monocot versus dicot, but rather one correlated with general pollen type: uniaperturate versus triaperturate. The Dilleniidae and Hamamelidae are the only subclasses that are grossly polyphyletic; an examination of the latter is presented as an example of the use of these broad analyses to focus more restricted studies. A broadly circumscribed Rosidae is paraphyletic to Asteridae and Dilleniidae. Subclass Caryophyllidae is monophyletic and derived from within Rosidae in the 475-taxon analysis but is sister to a group composed of broadly delineated Asteridae and Rosidae in the 499-taxon study

    Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

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    Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio
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