3,725 research outputs found
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Thaan Vuzha Nilam Tharisu: the land without a farmer becomes barren
This report forms a part of the international research project on policy and sustainable agriculture, Policies that Work for Sustainable Agriculture and Regenerated Rural Economies. The report details the findings of one of the constituent studies, undertaken by an Indian NGO, the Society for People's Education and Economic Change (SPEECH). The Importance of this project is that it concentrated on rainfed rather than irrigated agriculture - i.e. the sharp end of rural development in India, and that the focus was very much on the micro-level, looking at policy as seen from the ground. One of the recurring themes throughout the research was the importance of appreciating people as individuals, and in this spirit some of the personal qualities of the research team are shared. The research covers events in sites in the Virudhunagar district of Tamilnadu: Tiruchuli Panchayat Union and the Villur chain of tanks. This is an essentially rural area, where the need for sustainable forms of agriculture and rural livelihoods is clear. The political landscape is fractured and complex (§2.3), and the officials with the responsibility of implementing policy face significant obstacles and disincentives in doing so in response to the needs of local communities
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A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X.
BackgroundActivated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is embryonic or perinatal lethal.ObjectiveWe sought to generate a viable mouse model of FX deficiency.MethodsWe used a socket-targeting construct to generate F10-knockout mice by eliminating F10 exon 8 (knockout allele termed F10(tm1Ccmt), abbreviated as '-'; wild-type '+'), and a plug-targeting construct to generate mice expressing a FX variant with normal antigen levels but low levels of FX activity [4-9% normal in humans carrying the defect, Pro343-->Ser, termed FX Friuli (mutant allele termed F10(tm2Ccmt), abbreviated as F)].ResultsF10 knockout mice exhibited embryonic or perinatal lethality. In contrast, homozygous Friuli mice [F10 (F/F)] had FX activity levels of approximately 5.5% (sufficient to rescue both embryonic and perinatal lethality), but developed age-dependent iron deposition and cardiac fibrosis. Interestingly, F10 (-/F) mice with FX activity levels of 1-3% also showed complete rescue of lethality. Further study of this model provides evidence supporting a role of maternal FX transfer in the embryonic survival.ConclusionsWe demonstrate that, while complete absence of FX is incompatible with murine survival, minimal FX activity as low as 1-3% is sufficient to rescue the lethal phenotype. This viable low-FX mouse model will facilitate the development of FX-directed therapies as well as investigation of the FX role in embryonic development
Tele-operated high speed anthropomorphic dextrous hands with object shape and texture identification
This paper reports on the development of two number of robotic hands have been developed which focus on tele-operated high speed anthropomorphic dextrous robotic hands. The aim of developing these hands was to achieve a system that seamlessly interfaced between humans and robots. To provide sensory feedback, to a remote operator tactile sensors were developed to be mounted on the robotic hands. Two systems were developed, the first, being a skin sensor capable of shape reconstruction placed on the palm of the hand to feed back the shape of objects grasped and the second is a highly sensitive tactile array for surface texture identification
All work and no pay: consequences of unpaid work experience in the creative industries
This research note evaluates the benefits and pitfalls of unpaid work as an entry route into employment in the creative industries and investigates the consequences of this practice for those who already work in the sector. Based on a qualitative study of perspectives of stakeholders in unpaid work, this article argues that the social capital thesis, often used as a rationale for unpaid work, inadequately explains the practice of unpaid work experience, primarily because it does not take cognisance of the consequences of this practice for other people working in the sector. The study also highlights methodological issues that need to be considered in the future. As well as the importance of a plurality of stakeholder perspectives, the study emphasizes the need to consider the perspectives of those who are excluded from unpaid work and those who are potentially displaced by it
Phase Fluctuations near the Chiral Critical Point
The Helmholtz free energy density is parametrized as a function of
temperature and baryon density near the chiral critical point of QCD. The
parametrization incorporates the expected critical exponents and amplitudes. An
expansion away from equilibrium states is achieved with Landau theory. This is
used to calculate the probability that the system is found at a density other
than the equilibrium one. Such fluctuations are predicted to be very large in
heavy ion collisions.Comment: 7 pages, 8 figures, Winter Workshop on Nuclear Dynamics 201
Declination dependence of the cosmic-ray flux at extreme energies
We study the large-scale distribution of the arrival directions of the
highest energy cosmic rays observed by various experiments. Despite clearly
insufficient statistics, we find a deficit of cosmic rays at energies higher
than 10^{20} eV from a large part of the sky around the celestial North Pole.
We speculate on possible explanations of this feature.Comment: 5 pages, 4 figures; v2: 11 pages, 4 figures, title changed (to avoid
confusion with the Southern hemisphere), analysis extended, more data
included, results unchanged; to be published in JCA
Higher order eigenpair perturbations
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76914/1/AIAA-11149-583.pd
Hydrotalcite-derived copper-based oxygen carrier materials for efficient chemical-looping combustion of solid fuels with CO2 capture
Chemical-looping combustion (CLC) is a promising technology that utilizes metal oxides as oxygen carriers for the combustion of fossil fuels to CO2 and H2O, with CO2 readily sequestrated after the condensation of steam. Thermally stable and reactive metal oxides are desirable as oxygen carrier materials for the CLC processes. Here, we report the performance of Cu-based mixed oxides derived from hydrotalcite (also known as layered double hydroxides) precursors as oxygen carriers for the combustion of solid fuels. Two types of CLC processes were demonstrated, including chemical looping oxygen uncoupling (CLOU) and in situ gasification (iG-CLC) in the presence of steam. The Cu-based oxygen carriers showed high performance for the combustion of two solid fuels (a lignite and a bituminous coal), maintaining high thermal stability, fast reaction kinetics, and reversible oxygen release and storage over multiple redox cycles. Slight deactivation and sintering of the oxygen carrier occurred after redox cycles at an very high operation temperature of 985 °C. We expect that our material design strategy will inspire the development of better oxygen carrier materials for a variety of chemical looping processes for the clean conversion of fossil fuels with efficient CO2 capture
‘Talent-spotting’ or ‘social magic’? Inequality, cultural sorting and constructions of the ideal graduate in elite professions
Graduate outcomes – including rates of employment and earnings – are marked by persistent
inequalities related to social class, as well as gender, ethnicity and institution. Despite national
policy agendas related to social mobility and ‘fair access to the professions’, high-status occupations
are disproportionately composed of those from socially privileged backgrounds, and evidence
suggests that in recent decades many professions have become less socially representative.
This article makes an original contribution to sociological studies of inequalities in graduate
transitions and elite reproduction through a distinct focus on the ‘pre-hiring’ practices of graduate
employers. It does this through a critical analysis of the graduate recruitment material of two
popular graduate employers. It shows how, despite espousing commitments to diversity and
inclusion, constructions of the ‘ideal’ graduate privilege individuals who can mobilise and embody
certain valued capitals. Using Bourdieusian concepts of ‘social magic’ and ‘institutional habitus’, the
article argues that more attention must be paid to how graduate employers’ practices constitute
tacit processes of social exclusion and thus militate against the achievement of more equitable
graduate outcomes and fair access to the ‘top jobs
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