20,171 research outputs found

    Home monitoring of foot skin temperatures to prevent ulceration

    Get PDF
    OBJECTIVE - To evaluate the effectiveness of at-home infrared temperature monitoring as a preventative tool in individuals at high risk for diabetes-related lower-extremity ulceration and amputation. RESEARCH DESIGN AND METHODS - Eighty-five patients who fit diabetic foot risk category 2 or 3 (neuropathy and foot deformity or previous history of ulceration or partial foot amputation) were randomized into a standard therapy group (n = 41) or an enhanced therapy group (n = 44). Standard therapy consisted of therapeutic footwear, diabetic foot education, and regular foot evaluation by a podiatrist. Enhanced therapy included the addition of a handheld infrared skin thermometer to measure temperatures on the sole of the foot in the morning and evening. Elevated temperatures (>4°F compared with the opposite foot) were considered to be "at risk" of ulceration due to inflammation at the site of measurement. When foot temperatures were elevated, subjects were instructed to reduce their activity and contact the study nurse. Study subjects were followed for 6 months. RESULTS - The enhanced therapy group had significantly fewer diabetic foot complications (enhanced therapy group 2% vs. standard therapy group 20%, P = 0.01, odds ratio 10.3, 95% CI 1.2-85.3). There were seven ulcers and two Charcot fractures among standard therapy patients and one ulcer in the enhanced therapy group. CONCLUSIONS - These results suggest that at-home patient self-monitoring with daily foot temperatures may be an effective adjunctive tool to prevent foot complications in individuals at high risk for lower-extremity ulceration and amputation

    Analytical Rebridging Monte Carlo: Application to cis/trans Isomerization in Proline-Containing, Cyclic Peptides

    Get PDF
    We present a new method, the analytical rebridging scheme, for Monte Carlo simulation of proline-containing, cyclic peptides. The cis/trans isomerization is accommodated by allowing for two states of the amide bond. We apply our method to five peptides that have been previously characterized by NMR methods. Our simulations achieve effective equilibration and agree well with experimental data in all cases. We discuss the importance of effective equilibration and the role of bond flexibility and solvent effects on the predicted equilibrium properties.Comment: 29 pages, 8 PostScript figures, LaTeX source. to appear in J. Chem. Phys., 199

    Interpretation of the angular dependence of the de Haas-van Alphen effect in MgB_2

    Full text link
    We present detailed results for the amplitude and field dependence of the de Haas-van Alphen (dHvA) signal arising from the electron-like π\pi sheet of Fermi surface in MgB_2. Our data and analysis show that the dip in dHvA amplitude when the field is close to the basal plane is caused by a beat between two very similar dHvA frequencies and not a spin-zero effect as previously assumed. Our results imply that the Stoner enhancement factors in MgB_2 are small on both the Sigma and Pi sheets.Comment: 4 pages with figures. Submitted to PR

    A SOCIAL COGNITIVE THEORY PERSPECTIVE ON INDIVIDUAL REACTIONS TO COMPUTING TECHNOLOGY

    Get PDF
    Understanding individual reactions to computing technology is a central concern of information systems research. This research seeks to understand these reactions from the perspective of Social Cognitive Theory (Bandura 1977, 1978, 1982, 1986), a widely accepted theory of behavior in Social Psychology and Industrial/Organizational Psychology. The theory holds that behavior, environment, and cognitive and other individual factors are engaged in an ongoing reciprocal interaction. Two cognitive factors in particular are given prominence in the theory: (1) outcome expectations, or beliefs about the consequences of behavior and (2) self-efficacy, beliefs about one\u27s ability to successfully execute particular behaviors. A model of individual reactions to computing technology based on this theory was tested on a sample of 940 Canadian knowledge workers. Eleven of the fourteen hypotheses were supported by the analysis. Key findings were that self-efficacy, outcome expectations, affect and anxiety all had a direct influence on computer use. In addition, outcome expectations and self-efficacy were found to indirectly influence computer use through affect and anxiety. Tile behavior and influence of others in the individuals\u27 reference groups was found to exert a small influence on selfefficacy and outcome expectations

    Experimental phase diagram of moving vortices

    Full text link
    In the mixed state of type II superconductors, vortices penetrate the sample and form a correlated system due to the screening of supercurrents around them. Interestingly, we can study this correlated system as a function of density and driving force. The density, for instance, is controlled by the magnetic field, B, whereas a current density j acts as a driving force F=jxB on all vortices. The free motion of vortices is inhibited by the presence of an underlying potential, which tends to pin the vortices. Hence, to minimize the pinning strength we studied a superconducting glass in which the depinning current is 10 to 1000 times smaller than in previous studies, which enables us to map out the complete phase diagram in this new regime. The diagram is obtained as a function of B, driving current and temperature and led a remarkable set of new results, which includes a huge peak effect, an additional reentrant depinning phase and a driving force induced pinning phase.Comment: 4 page

    An Annotated Bibliography: Published Articles (1861-1998) About the Wild Mammals of South Dakota

    Get PDF
    Our goal in compiling this bibliography was to locate every published article with a connection to any wild South Dakota mammal. However, we understood from the start that this goal would be unattainable. Consequently, this collection can provide only a point of origin to readers interested in obtaining published studies (popular and scientific) about the wild mammals of South Dakota
    corecore