Studi Karakteristik Lahan Parkir di Rumah Sakit Mitra Keluarga Cibubur

Masalah parkir kendaraan bermotor di Rumah Sakit Mitra Keluarga Cibubur saat ini, berhubungan erat dengan kebutuhan ruang parkir, sehingga dampak yang timbul akibat parkir kendaraan bermotor yang tidak teratur akan mengganggu kegiatan lainnya.Gambaran permasalahan parkir didapat melalui survai yang bertujuan untuk memaparkan data dari objek penelitian dan menganalisanya secara sistematis sehingga dapat mengetahui secara tepat permasalahan yang ada dalam menyelesaikan permasalahan tersebut, kemudian dilakukan pengolahan data menggunakan Microsoft Excel. Dari hasil survai yang dilakukan selama 7 hari dengan waktu pengamatan 12 jam/hari diperoleh volume parkir mobil maksimum 346 kendaraan dan 262 kendaraan untuk volume parkir motor, akumulasi parkir mobil maksimum 111 kendaraan/jam dan 80 kendaraan/jam untuk akumulasi parkir motor, indeks parkir mobil maksimum pada hari Minggu sebesar 38,58% dan 30,62% untuk indeks parkir motor, durasi parkir mobil yang paling lama yaitu selama dua jam atau 36,88% dari kendaraan yang parkir dan dua jam atau 37,20% dari kendaraan yang parkir untuk durasi parkir motor, pergantian parkir (turn over parking) mobil tertinggi pada hari Minggu pergantian parkir sebanyak 1,48 kendaraan/petak. Pergantian parkir (turn over parking) motor tertinggi terjadi pada hari Minggu, dengan pergantian parkir sebanyak 1,24 kendaraan/petak. Lahan parkir yang disediakan Rumah Sakit Mitra Keluarga Cibubur belum diperlukan penambahan lahan parkir pada tahun ini. Kata kunci: volume parkir, akumulasi parkir, indeks parkir, durasi parkir dan pergantian parkir (turn over parking

Penyebaran Dan Pembauran Inovasi Gizi Melalui Kegiatan Upgk Di Pedesaan Jawa Barat

Kegiatan Usaha Perbaikan Gizi Keluarga (UPGK) di Pos Pelayanan Terpadu (Posyandu) dapat dipandang sebagai upaya pembaruan perilaku (konsumsi) yang bertujuan agar lambat laun ibu-ibbu anak Balita atas bantuan para kader memiliki kemampuan mandiri dalam memelihara dan meningkatkan derajat kesehatan dan gizi anak Balita serta keluarga mereka. Upaya ini akan mempunyai arti positif jika pada sistem sosial masyarakat bertumbuh dan berkembang proses belajar dan pembaruan perilaku yang mengarah pada tindakan masing-masing keluarga untuk hidup lebih sehat dibanding keadaan sebelumnya. Pencapaian keadaan seperti ini tidak lepas dari fungsi dan peranan para pembina serta kader yang terlibat dalam kegiatan tersebut selaku sumber dan penyalur pesan-pesan inovasi gizi. Kenyataan menunjukkan bahwa pelaksanaan program belum mencapai sasaran sebagaimana yang diharapkan. Dalam tulisan ini dikemukakan beberapa faktor penyebab ketidakberhasilan pencapaian sasaran program UPGK, khususnya di Kabupaten Subang, Jawa Barat, dimana identifikasi masalah dilakukan. kemampuan ekonomi keluarga dan tingkat pendidikan ibu anak Balita yang relatif rendah menjadi kendala utama yang mempengaruhi kadar pengetahuan gizi mereka. Para kader dihadapkan pada masalah kurang mengikuti penataran, cakupan wilayah kerja yang terlalu luas, ketidakjelasan keterikatan mereka dalam kegiatan, dan sistem imbalan, suasana yang kurang memadai di Posyandu sebagai tempat penyuluhan gizi bagi ibu-ibu peserta kegiatan UPGK, keterbatasan kesempatan, dana dan sarana untuk kegiatan kunjungan rumah. Petugas gizi selaku pembina kegiatan di Posyandu menghadapi keterbatasan sarana transportasi, disamping tugas rutin yang cukup banyak menyita perhatian dan waktu

Studi Awal Estimasi Dosis Internal 177lu-dota Trastuzumab pada Manusia Berbasis Uji Biodistribusi pada Mencit

STUDI AWAL ESTIMASI DOSIS INTERNAL 177Lu-DOTA TRASTUZUMAB PADA MANUSIA BERBASIS UJI BIODISTRIBUSI PADA MENCIT. Radiofarmaka baru untuk pengobatan penyakit kanker payudara tipe HER-2, 177Lu-DOTA Trastuzumab, telah berhasil diproduksi oleh Pusat Teknologi Radioisotop dan Radiofarmaka (PTRR) BATAN. Demi keamanan produk dan keselamatan pasien, radiofarmaka baru tersebut perlu dilengkapi dengan data studi dosis internal yang dilakukan setelah uji praklinis pada hewan coba selesai. Oleh karena itu, studi ini bertujuan untuk melakukan estimasi dosis pada pasien yang dihitung berdasarkan data uji biodistribusi pada mencit. Studi Uji biodistribusi dilakukan pada 25 ekor mencit dan diamati biodistribusinya pada organ-organ, diantaranya otak, Perut, usus, jantung , ginjal, hati, paru-paru, otot, tulang, limpa dan kandung kemih. Pengamatan cacahan organ dilakukan pada jam ke 1, 2, 3, 4, 24, 48 pasca injeksi radiofarmaka 177Lu DOTA-Trastuzumab sebesar 100mCi. Hasil yang diperoleh dari uji biodistribusi adalah % ID/gram organ tikus, kemudian dilakukan konversi perhitungan ke % ID/gram organ manusia. Untuk mengestimasi dosis ke manusia, hasil %ID/gram organ tersebut dipakai sebagai input pada software dosimetri internal OLINDA/EXM, dengan cara melakukan plotting %ID/gram versus waktu, yang akan menghasilkan residence time di masing-masing organ. Setelah residence time diperoleh, dosis internal radiasi pada masing-masing organ dan seluruh tubuh dapat diketahui. Hasil studi menunjukkan bahwa tiga organ yang memiliki dosis internal tertinggi 177Lu DOTA Trastuzumab adalah : paru-paru, hati dan ovarium dengan dosis masing-masing 0,063; 0,046 dan 0,025 mSv/MBq. Disimpulkan bahwa hasil estimasi dosis internal radiasi total yang diperoleh manusia pada penyuntikan radiofarmaka 177Lu-DOTA Trastuzumab adalah 0.21 mSv/MBq

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

Isolation-Amplification of ENV-TM Subunit Genes of Jembrana Disease Virus by a Single Step RT-PCR and Its Direct Cloning in PCR2.1-TOPO Plasmid

Artikel dalam bentuk PD

International Impact of COVID-19 on the Diagnosis of Heart Disease

Background: The coronavirus disease 2019 (COVID-19) pandemic has adversely affected diagnosis and treatment of noncommunicable diseases. Its effects on delivery of diagnostic care for cardiovascular disease, which remains the leading cause of death worldwide, have not been quantified. Objectives: The study sought to assess COVID-19's impact on global cardiovascular diagnostic procedural volumes and safety practices. Methods: The International Atomic Energy Agency conducted a worldwide survey assessing alterations in cardiovascular procedure volumes and safety practices resulting from COVID-19. Noninvasive and invasive cardiac testing volumes were obtained from participating sites for March and April 2020 and compared with those from March 2019. Availability of personal protective equipment and pandemic-related testing practice changes were ascertained. Results: Surveys were submitted from 909 inpatient and outpatient centers performing cardiac diagnostic procedures, in 108 countries. Procedure volumes decreased 42% from March 2019 to March 2020, and 64% from March 2019 to April 2020. Transthoracic echocardiography decreased by 59%, transesophageal echocardiography 76%, and stress tests 78%, which varied between stress modalities. Coronary angiography (invasive or computed tomography) decreased 55% (p &lt; 0.001 for each procedure). In multivariable regression, significantly greater reduction in procedures occurred for centers in countries with lower gross domestic product. Location in a low-income and lower–middle-income country was associated with an additional 22% reduction in cardiac procedures and less availability of personal protective equipment and telehealth. Conclusions: COVID-19 was associated with a significant and abrupt reduction in cardiovascular diagnostic testing across the globe, especially affecting the world's economically challenged. Further study of cardiovascular outcomes and COVID-19–related changes in care delivery is warranted

Impact of COVID-19 on Diagnostic Cardiac Procedural Volume in Oceania: The IAEA Non-Invasive Cardiology Protocol Survey on COVID-19 (INCAPS COVID)

Objectives: The INCAPS COVID Oceania study aimed to assess the impact caused by the COVID-19 pandemic on cardiac procedure volume provided in the Oceania region. Methods: A retrospective survey was performed comparing procedure volumes within March 2019 (pre-COVID-19) with April 2020 (during first wave of COVID-19 pandemic). Sixty-three (63) health care facilities within Oceania that perform cardiac diagnostic procedures were surveyed, including a mixture of metropolitan and regional, hospital and outpatient, public and private sites, and 846 facilities outside of Oceania. The percentage change in procedure volume was measured between March 2019 and April 2020, compared by test type and by facility. Results: In Oceania, the total cardiac diagnostic procedure volume was reduced by 52.2% from March 2019 to April 2020, compared to a reduction of 75.9% seen in the rest of the world (p&lt;0.001). Within Oceania sites, this reduction varied significantly between procedure types, but not between types of health care facility. All procedure types (other than stress cardiac magnetic resonance [CMR] and positron emission tomography [PET]) saw significant reductions in volume over this time period (p&lt;0.001). In Oceania, transthoracic echocardiography (TTE) decreased by 51.6%, transoesophageal echocardiography (TOE) by 74.0%, and stress tests by 65% overall, which was more pronounced for stress electrocardiograph (ECG) (81.8%) and stress echocardiography (76.7%) compared to stress single-photon emission computerised tomography (SPECT) (44.3%). Invasive coronary angiography decreased by 36.7% in Oceania. Conclusion: A significant reduction in cardiac diagnostic procedure volume was seen across all facility types in Oceania and was likely a function of recommendations from cardiac societies and directives from government to minimise spread of COVID-19 amongst patients and staff. Longer term evaluation is important to assess for negative patient outcomes which may relate to deferral of usual models of care within cardiology