Making the implicit explicit: raising pragmatic awareness in trainee interpreters, using semi-authentic spontaneous discourse samples

Following the recent interest in the teaching of pragmatics and the recognition of its importance for both cross-cultural communication and new speakers of an additional language, the authors carried out an action research project to evaluate the effectiveness of a new approach to the teaching of pragmatics. This involved the use of semiauthentic discourse samples of New Zealand English to raise the pragmatic awareness of trainee interpreters in an undergraduate course taught by the first author. The researchers analysed qualitative data from learner blogs, written during instruction as part of the course requirements, for evidence that the learners noticed paralinguistic features used for pragmatic effect in conversations they overheard or took part in outside the classroom. The class teacher also kept a reflective journal recording her observations on learner progress and the usefulness of the materials. The researchers found there was a growth in the number of learners noticing pragmatic features during tuition, suggesting that the semiauthentic samples were effective as learning tools. Use of these samples also facilitated the noticing and discussion of cross-cultural differences and enabled more learner-centered methodology to be used

Local well-posedness for the nonlinear Schr\"odinger equation in the intersection of modulation spaces Mp,qs(Rd)∩M∞,1(Rd)M_{p, q}^s(\mathbb{R}^d) \cap M_{\infty, 1}(\mathbb{R}^d)

We introduce a Littlewood-Paley characterization of modulation spaces and use it to give an alternative proof of the algebra property, somehow implicitly contained in Sugimoto (2011), of the intersection $M^s_{p,q}(\mathbb{R}^d) \cap M_{\infty, 1}(\mathbb{R}^d)$ for $d \in \mathbb{N}$, $p, q \in [1, \infty]$ and $s \geq 0$. We employ this algebra property to show the local well-posedness of the Cauchy problem for the cubic nonlinear Schr\"odinger equation in the above intersection. This improves Theorem 1.1 by B\'enyi and Okoudjou (2009), where only the case $q = 1$ is considered, and closes a gap in the literature. If $q > 1$ and $s > d \left(1 - \frac{1}{q}\right)$ or if $q = 1$ and $s \geq 0$ then $M^s_{p,q}(\mathbb{R}^d) \hookrightarrow M_{\infty, 1}(\mathbb{R}^d)$ and the above intersection is superfluous. For this case we also reobtain a H\"older-type inequality for modulation spaces.Comment: 14 page

Business Case Control in Project Portfolios - An Empirical Investigation of Performance Consequences and Moderating Effects

© 1988-2012 IEEE. Practitioners place strong emphasis on business cases with the expectation that using business cases to inform and drive investment decisions will assist in creating value from those investments. Maximizing the value generated by project investments is a central aim of the project portfolio management, and the business case provides the underlying rationale for the evaluation of the value created in each project. However, research regarding the use of business cases at a project portfolio level is scarce, and there is a little guidance for portfolio managers on when and how to control the business cases. We identify three elements of a business case control at the portfolio level - the initial review, the ongoing monitoring during the project execution, and the postproject tracking until the business case is realized - and investigate the relationship between business case control and project portfolio success. Furthermore, we analyze enablers and contingencies for the application of the business case control. Based on a cross-industry sample of 183 firms, we find that the business case control is positively related to the project portfolio success. Accountability for business case realization and corresponding incentive systems increase this positive effect. Finally, we show that the portfolio complexity also positively moderates the relationship

The Role of Innovation Portfolio Management in the Nexus between Deliberate and Emergent Innovation Strategies

Planning and implementing innovation strategies are typically considered to be top-down processes and innovation portfolio management plays a decisive role in this context by aligning the project portfolio to the firm’s strategy. However, in strategic management research it is well accepted that strategies are not solely deliberate but can also be emergent. Thus, between top-down innovation strategy formulation and its implementation, responding dialectic elements are required to sense emerging strategic impetuses and cope with changing environmental conditions. This paper addresses the role of portfolio management in the nexus between strategy formulation and implementation. Using a sample of 182 medium and large firms with two informants, we show that portfolio management not only fosters the implementation of intended innovation strategies through vertical integration but also discloses strategic opportunities by unveiling emerging patterns. The findings show that portfolio management contributes to innovation portfolio success by supporting both the implementation of deliberate and emergent strategies through vertical integration and strategic disclosure. The effects are complementary in that both activities increase the positive effects of the other. Furthermore we find that strategic control (i.e. premise control, implementation control, and strategic surveillance) on a portfolio level indirectly contributes to success mediated by vertical integration and strategic disclosure. Finally, we show that the influence of vertical integration on innovation portfolio success is reduced under high environmental turbulence

Acute toxicity and behavioral changes of Caspian kutum (Rutilus frisii Kutum Kamensky, 1991) and Caspian roach (Rutilus rutilus caspicus Jakowlew, 1870) exposed to the fungicide hinosan

Pesticides are used in agriculture to control pest and protect human health and animals. Excessive use of pesticides caused risk for human health and threated non-target organisms, polluted water, soil and air. Hinosan is a component of organophosphate pesticide which is used as a fungicide in agricultural fields. In the study, lethal concentration (LC50) of Hinosan was calculated for Rutilus frisii kutum and Rutilus rutilus caspicus with a mean weight of 3 ± 1 g [mean ± SD]. The experiment were carried out in static condition and based on instructions of O.E.C.D in four days under controlled water physicochemical factors with pH = 7 to 8.5, dissolved oxygen = 200 mg L-1 (CaCO3) and temperature = 20 ± 1°C. Fishes were acclimatized in 70x40x30 cm aquarium for 10 days. Five treated aquariums with concentration ranges 1, 2, 4, 8, 16 ppm of hinosan (Technical 95 Edifenphos) with one control group (no toxic concentration), were performed. Data were analysed using the probit analysis. LC1, LC10, LC30, LC50, LC70, LC90 and LC99 were calculated in 24, 48, 72 and 96 h. Our results indicate that LC50 96 h hinosan for R. frisii Kutum and R. rutilus caspicus were obtained 3.61 and 2.88 ppm, respectively. These findings suggest that hinosan is medium toxicity for these two species. Clinical symptoms including irregular protrusion of the eyes and irregular swimming were observed.Key words: Organophosphore, hinosan, Rutilus frisii kutum, Rutilus rutilus caspicus, LC50, pollution

Predictors of recovery rate among undernourished HIV-positive adults treated with ready-to-use therapeutic food at Debre Markos Comprehensive Specialized Hospital: A retrospective cohort study

Background Nutritional support is becoming more widely acknowledged as a crucial component of the key package of care for HIV/AIDS patients. This nutritional support is exceptionally important for patients in sub-Saharan Africa, including Ethiopia, where HIV/AIDS is very prevalent. However, there is a lack of evidence on the recovery rate and predictors at the study site and at large in Ethiopia. Therefore, this study will give some insight into the recovery rate and its predictors among under-nourished HIV-positive adults treated with Ready to Use Therapeutic Food (RUTF) attending at Debre Markos referral hospital. Moreover, the findings of this study will be used by both governmental and non-governmental organizations to allocate more resources to mitigate the nutritional problems for people living with HIV. Methods An institution-based retrospective cohort study was conducted among 453 under-nourished HIV positive adults treated with RUTF at Debre Markos referral Hospital from the 1st of July, 2015 to the 31st of December, 2017. The study participants were selected using a simple random sampling technique. Data were extracted from patient charts using a standardized data extraction checklist. Data were entered into Epi-Data Version 4.2 and analyzed using Stata Version 14. The Kaplan-Meier survival curve was used to estimate the time to recovery. Log-rank test was used to compare the recovery time between different baseline categorical variables. The bivariable and multivariable Cox-proportional hazard regression models were fitted for potential predictors of recovery time. Adjusted hazard Ratios (AHRs) with 95% CIs were used to measure the strength of association and test statistical significance. Results A total of 453 undernourished HIV-positive adults were included in the final analysis. About 201, 44.4% (95%CI: 38.9, 49.0%) patients participating in the RUTF program were recovered based on predetermined exit criteria with incidence of 10.65 (95% CI: 9.28, 12.23) per 100 person-month observations. Being moderately undernourished (AHR: 11.0, 95% CI: 5.3, 23.1), WHO clinical stage (I or II) (AHR:1.8, 95% CI: 1.2, 2.6), and working functional status at baseline (AHR = 2.34, 95%CI: 1.01,5.45) were predictors of recovery time. Conclusion This study concluded that the overall nutritional recovery rate was below the acceptable minimum requirement which at least 75% of patients should recovered. Mild to moderate undernutrition at baseline, WHO clinical stage I or II at enrolment, and working functional status were found to be predictors of recovery time in HIV/AIDS patients treated with the RUTF. As a result, special attention should be paid to severely malnourished patients, WHO clinical stages III or higher, and patients who are bedridden or ambulatory during treatment

The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients

Background and Objectives. Detection of PML-RAR alpha transcripts by RT-PCR is now established as a rapid and sensitive method for diagnosis of acute promyelocytic leukemia (APL), Although the majority of patients in longterm clinical remission are negative by consecutive reverse transcription polymerase chain reaction (RT-PCR) assays, negative tests are still observed in patients who ultimately relapse. Conversion from negative to positive PCR has been observed after consolidation and found to be a much stronger predictor of relapse. This study reports on 47 APL patients to determine the correlation between minimal residual disease (MRD) status and clinical outcome in our cohort of patients. Design and Methods. The presence of PML-RAR alpha t transcripts was investigated in 47 APL patients (37 adults and 10 children) using a semi-nested reverse transcriptase-polymerase chain reaction to evaluate the prognostic value of RT-PCR tests. Results. All patients achieved complete clinical remission (CCR) following induction treatment with all-trans retinoic acid (ATRA) and chemotherapy (CHT) or ATRA alone. Patients were followed up between 2 and 117.6 months (median: 37 months). Relapses occurred in 11 patients (9 adults and 2 children) between 11.4 and 19 months after diagnosis (median: 15.1 months) while 36 patients (28 adults and 8 children) remained in CCR, Seventy-five percent of patients carried the PML-RARa long isoform (bcr 1/2) which also predominated among the relapsed cases (9 of 11) but did not associate with any adverse outcome (p = 0.37), For the purpose of this analysis, minimal residual disease tests were clustered into four time-intervals: 0-2 months, 3-5 months, 5-9 months and 10-24 months. Interpretation and Conclusions. Children showed persisting disease for longer than adults during the first 2 months of treatment, At 2 months, 10 (50%) of 20 patients who remained in CCR and 4 (80%) of 5 patients who subsequently relapsed were positive. Patients who remained in CCR had repeatedly negative results beyond 5.5 months from diagnosis. A positive MRD test preceded relapse in 3 of 4 tested patients. The ability of a negative test to predict CCR (predictive negative value, PNV) was greater after 6 months (> 83%), while the ability of a positive test to predict relapse (predictive positive value, PPV) was most valuable only beyond 10 months (100%). This study (i) highlights the prognostic value of RT-PCR monitoring after treatment of APL patients but only from the end of treatment, (ii) shows an association between conversion to a positive test and relapse and (iii) suggests that PCR assessments should be carried out at 3-month intervals to provide a more accurate prediction of hematologic relapses but only after the end of treatment, (C) 2001, Ferrata Storti Foundatio