12 research outputs found

    Emerging concepts in biomarker discovery; The US-Japan workshop on immunological molecular markers in oncology

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    Supported by the Office of International Affairs, National Cancer Institute (NCI), the "US-Japan Workshop on Immunological Biomarkers in Oncology" was held in March 2009. The workshop was related to a task force launched by the International Society for the Biological Therapy of Cancer (iSBTc) and the United States Food and Drug Administration (FDA) to identify strategies for biomarker discovery and validation in the field of biotherapy. The effort will culminate on October 28th 2009 in the "iSBTc-FDA-NCI Workshop on Prognostic and Predictive Immunologic Biomarkers in Cancer", which will be held in Washington DC in association with the Annual Meeting. The purposes of the US-Japan workshop were a) to discuss novel approaches to enhance the discovery of predictive and/or prognostic markers in cancer immunotherapy; b) to define the state of the science in biomarker discovery and validation. The participation of Japanese and US scientists provided the opportunity to identify shared or discordant themes across the distinct immune genetic background and the diverse prevalence of disease between the two Nations

    Aligning business process reengineering in implementing global supply chain systems by the SCOR model

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    International audienceAs supply chains continue to replace individual companies as the management arena for value-adding from the beginning of the twenty first century, understanding the supply chain management practices in a globalization context becomes increasingly important. The Supply Chain Operations Reference (SCOR) Model, which was developed by the experts and practitioners of the Supply Chain Council, is a major framework for supply chain planning which features supply chain management practices and business process reengineering. Despite being an integrative guide with many merits, it only provides a ‘top-down' approach which requires the comparative analyses of post- and pro- performance indices as a basis of business process modification. This study discusses the limitations of current SCOR analysis and provides a mapping technique— Causes/Effects, the SCOR Standard, and Mutual Solution (CESM)—for gap mapping, problem prioritization, and business process modification in a supply chain setting. As such it is one of the early empirical studies combining BPR and SCM disciplines. The research results can facilitate the implementation processes of multinational supply chain projects by identifying the gaps and linking them to the channel entities
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