14,518 research outputs found
On the Birth of Isolas
Isolas are isolated, closed curves of solution branches of nonlinear problems. They have been observed to occur in the buckling of elastic shells, the equilibrium states of chemical reactors and other problems. In this paper we present a theory to describe analytically the structure of a class of isolas. Specifically, we consider isolas that shrink to a point as a parameter Ï„ of the problem, approaches a critical value Ï„_0. The point is referred to as an isola center. Equations that characterize the isola centers are given. Then solutions are constructed in a neighborhood of the isola centers by perturbation expansions in a small
parameter ε that is proportional to (τ-τo), with a appropriately determined. The theory is applied to a
chemical reactor problem
Gallium Arsenide preparation and QE Lifetime Studies using the ALICE Photocathode Preparation Facility
In recent years, Gallium Arsenide (GaAs) type photocathodes have become
widely used as electron sources in modern Energy Recovery Linac based light
sources such as the Accelerators and Lasers in Combined Experiments (ALICE) at
Daresbury Laboratory and as polarised electron source for the proposed
International Linear Collider (ILC). Once activated to a Low Electron Affinity
(LEA) state and illuminated by a laser, these materials can be used as a
high-brightness source of both polarised and un-polarised electrons. This paper
presents an effective multi-stage preparation procedure including heat
cleaning, atomic hydrogen cleaning and the activation process for a GaAs
photocathode. The stability of quantum efficiency (QE) and lifetime of
activated to LEA state GaAs photocathode have been studied in the ALICE
load-lock photocathode preparation facility which has a base pressure in the
order of 10^-11 mbar. These studies are supported by further experimental
evidence from surface science techniques such as X-ray Photoelectron
Spectroscopy (XPS) to demonstrate the processes at the atomic level.Comment: Presented at First International Particle Accelerator Conference,
IPAC'10, Kyoto, Japan, from 23 to 28 May 201
Space biology initiative program definition review. Trade study 4: Design modularity and commonality
The relative cost impacts (up or down) of developing Space Biology hardware using design modularity and commonality is studied. Recommendations for how the hardware development should be accomplished to meet optimum design modularity requirements for Life Science investigation hardware will be provided. In addition, the relative cost impacts of implementing commonality of hardware for all Space Biology hardware are defined. Cost analysis and supporting recommendations for levels of modularity and commonality are presented. A mathematical or statistical cost analysis method with the capability to support development of production design modularity and commonality impacts to parametric cost analysis is provided
Space biology initiative program definition review. Trade study 3: Hardware miniaturization versus cost
The optimum hardware miniaturization level with the lowest cost impact for space biology hardware was determined. Space biology hardware and/or components/subassemblies/assemblies which are the most likely candidates for application of miniaturization are to be defined and relative cost impacts of such miniaturization are to be analyzed. A mathematical or statistical analysis method with the capability to support development of parametric cost analysis impacts for levels of production design miniaturization are provided
Dynamic instabilities of fracture under biaxial strain using a phase field model
We present a phase field model of the propagation of fracture under plane
strain. This model, based on simple physical considerations, is able to
accurately reproduce the different behavior of cracks (the principle of local
symmetry, the Griffith and Irwin criteria, and mode-I branching). In addition,
we test our model against recent experimental findings showing the presence of
oscillating cracks under bi-axial load. Our model again reproduces well
observed supercritical Hopf bifurcation, and is therefore the first simulation
which does so
Quantum computation with trapped ions in an optical cavity
Two-qubit logical gates are proposed on the basis of two atoms trapped in a
cavity setup. Losses in the interaction by spontaneous transitions are
efficiently suppressed by employing adiabatic transitions and the Zeno effect.
Dynamical and geometrical conditional phase gates are suggested. This method
provides fidelity and a success rate of its gates very close to unity. Hence,
it is suitable for performing quantum computation.Comment: 4 pages, 5 figures, REVTEX, second part modified, typos correcte
Use of ERTS-1 data in identification, classification, and mapping of salt-affected soils in California
There are no author-identified significant results in this report
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Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation.
Chemotherapy-induced peripheral neuropathy (CIPN) is a severe and dose-limiting side effect of cancer treatment that affects millions of cancer survivors throughout the world and current treatment options are extremely limited by their side effects. Cannabinoids are highly effective in suppressing pain symptoms of chemotherapy-induced and other peripheral neuropathies but their widespread use is limited by central nervous system (CNS)-mediated side effects. Here, we tested one compound from a series of recently developed synthetic peripherally restricted cannabinoids (PRCBs) in a rat model of cisplatin-induced peripheral neuropathy. Results show that local or systemic administration of 4-{2-[-(1E)-1[(4-propylnaphthalen-1-yl)methylidene]-1H-inden-3-yl]ethyl}morpholine (PrNMI) dose-dependently suppressed CIPN mechanical and cold allodynia. Orally administered PrNMI also dose-dependently suppressed CIPN allodynia symptoms in both male and female rats without any CNS side effects. Co-administration with selective cannabinoid receptor subtype blockers revealed that PrNMI's anti-allodynic effects are mediated by CB1 receptor (CB1R) activation. Expression of CB2Rs was reduced in dorsal root ganglia from CIPN rats, whereas expression of CB1Rs and various endocannabinoid synthesizing and metabolizing enzymes was unaffected. Daily PrNMI treatment of CIPN rats for two weeks showed a lack of appreciable tolerance to PrNMI's anti-allodynic effects. In an operant task which reflects cerebral processing of pain, PrNMI also dose-dependently suppressed CIPN pain behaviors. Our results demonstrate that PRCBs exemplified by PrNMI may represent a viable option for the treatment of CIPN pain symptoms
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