2,465 research outputs found
Dimensional instability of aluminum alloys for extreme low temperature cycling applications /GGV material instability problem/
Dimensional instability of aluminum alloys during cryogenic thermal cyclin
Age of second language acquisition affects nonverbal conflict processing in children : an fMRI study
Background: In their daily communication, bilinguals switch between two languages, a process that involves the selection of a target language and minimization of interference from a nontarget language. Previous studies have uncovered the neural structure in bilinguals and the activation patterns associated with performing verbal conflict tasks. One question that remains, however is whether this extra verbal switching affects brain function during nonverbal conflict tasks.
Methods: In this study, we have used fMRI to investigate the impact of bilingualism in children performing two nonverbal tasks involving stimulus-stimulus and stimulus-response conflicts. Three groups of 8-11-year-old children - bilinguals from birth (2L1), second language learners (L2L), and a control group of monolinguals (1L1) - were scanned while performing a color Simon and a numerical Stroop task. Reaction times and accuracy were logged.
Results: Compared to monolingual controls, bilingual children showed higher behavioral congruency effect of these tasks, which is matched by the recruitment of brain regions that are generally used in general cognitive control, language processing or to solve language conflict situations in bilinguals (caudate nucleus, posterior cingulate gyrus, STG, precuneus). Further, the activation of these areas was found to be higher in 2L1 compared to L2L.
Conclusion: The coupling of longer reaction times to the recruitment of extra language-related brain areas supports the hypothesis that when dealing with language conflicts the specialization of bilinguals hampers the way they can process with nonverbal conflicts, at least at early stages in life
Approaching the adiabatic timescale with machine-learning
The control and manipulation of quantum systems without excitation is
challenging, due to the complexities in fully modeling such systems accurately
and the difficulties in controlling these inherently fragile systems
experimentally. For example, while protocols to decompress Bose-Einstein
condensates (BEC) faster than the adiabatic timescale (without excitation or
loss) have been well developed theoretically, experimental implementations of
these protocols have yet to reach speeds faster than the adiabatic timescale.
In this work, we experimentally demonstrate an alternative approach based on a
machine learning algorithm which makes progress towards this goal. The
algorithm is given control of the coupled decompression and transport of a
metastable helium condensate, with its performance determined after each
experimental iteration by measuring the excitations of the resultant BEC. After
each iteration the algorithm adjusts its internal model of the system to create
an improved control output for the next iteration. Given sufficient control
over the decompression, the algorithm converges to a novel solution that sets
the current speed record in relation to the adiabatic timescale, beating out
other experimental realizations based on theoretical approaches. This method
presents a feasible approach for implementing fast state preparations or
transformations in other quantum systems, without requiring a solution to a
theoretical model of the system. Implications for fundamental physics and
cooling are discussed.Comment: 7 pages main text, 2 pages supporting informatio
Aligning physical elements with persons' attitude: an approach using Rasch measurement theory
Affective engineering uses mathematical models to convert the information obtained from persons' attitude to physical elements into an ergonomic design. However, applications in the domain have not in many cases met measurement assumptions. This paper proposes a novel approach based on Rasch measurement theory to overcome the problem. The research demonstrates that if data fit the model, further variables can be added to a scale. An empirical study was designed to determine the range of compliance where consumers could obtain an impression of a moisturizer cream when touching some product containers. Persons, variables and stimulus objects were parameterised independently on a linear continuum. The results showed that a calibrated scale preserves comparability although incorporating further variables
Park\u27s Tribolium Competition Experiments: A Non-equilibrium Species Coexistence Hypothesis
1. In this journal 35 years ago, P. H. Leslie, T. Park and D. B. Mertz reported competitive exclusion data for two Tribolium species. It is less well-known that they also reported \u27difficult to interpret\u27 coexistence data. We suggest that the species exclusion and the species coexistence are consequences of a stable coexistence two-cycle in the presence of two stable competitive exclusion equilibria. 2. A stage-structured insect population model for two interacting species forecasts that as interspecific interaction is increased there occurs a sequence of dynamic changes (bifurcations) in which the classic Lotka-Volterra-type scenario with two stable competitive exclusion equilibria is altered abruptly to a novel scenario with three locally stable entities; namely, two competitive exclusion equilibria and a stable coexistence cycle. This scenario is novel in that it predicts the competitive coexistence of two nearly identical species on a single limiting resource and does so under circumstances of increased interspecific competition. This prediction is in contradiction to classical tenets of competition theory
Lattice effects observed in chaotic dynamics of experimental populations
Animals and many plants are counted in discrete units. The collection of possible values (state space) of population numbers is thus a nonnegative integer lattice. Despite this fact, many mathematical population models assume a continuum of system states. The complex dynamics, such as chaos, often displayed by such continuous-state models have stimulated much ecological research; yet discretestate models with bounded population size can display only cyclic behavior. Motivated by data from a population experiment, we compared the predictions of discrete-state and continuous-state population models. Neither the discrete- nor continuous-state models completely account for the data. Rather, the observed dynamics are explained by a stochastic blending of the chaotic dynamics predicted by the continuous-state model and the cyclic dynamics predicted by the discretestate models. We suggest that such lattice effects could be an important component of natural population fluctuations. The discovery that simple deterministic population models can display complex aperiodi
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The use of large animals to facilitate the process of MSC going from laboratory to patient—‘bench to bedside’
Abstract: Large animal models have been widely used to facilitate the translation of mesenchymal stem cells (MSC) from the laboratory to patient. MSC, with their multi-potent capacity, have been proposed to have therapeutic benefits in a number of pathological conditions. Laboratory studies allow the investigation of cellular and molecular interactions, while small animal models allow initial ‘proof of concept’ experiments. Large animals (dogs, pigs, sheep, goats and horses) are more similar physiologically and structurally to man. These models have allowed clinically relevant assessments of safety, efficacy and dosing of different MSC sources prior to clinical trials. In this review, we recapitulate the use of large animal models to facilitate the use of MSC to treat myocardial infarction—an example of one large animal model being considered the ‘gold standard’ for research and osteoarthritis—an example of the complexities of using different large animal models in a multifactorial disease. These examples show how large animals can provide a research platform that can be used to evaluate the value of cell-based therapies and facilitate the process of ‘bench to bedside’
Recommended from our members
The use of large animals to facilitate the process of MSC going from laboratory to patient—‘bench to bedside’
Abstract: Large animal models have been widely used to facilitate the translation of mesenchymal stem cells (MSC) from the laboratory to patient. MSC, with their multi-potent capacity, have been proposed to have therapeutic benefits in a number of pathological conditions. Laboratory studies allow the investigation of cellular and molecular interactions, while small animal models allow initial ‘proof of concept’ experiments. Large animals (dogs, pigs, sheep, goats and horses) are more similar physiologically and structurally to man. These models have allowed clinically relevant assessments of safety, efficacy and dosing of different MSC sources prior to clinical trials. In this review, we recapitulate the use of large animal models to facilitate the use of MSC to treat myocardial infarction—an example of one large animal model being considered the ‘gold standard’ for research and osteoarthritis—an example of the complexities of using different large animal models in a multifactorial disease. These examples show how large animals can provide a research platform that can be used to evaluate the value of cell-based therapies and facilitate the process of ‘bench to bedside’
Modeling Risk for Child Abuse and Harsh Parenting in Families with Depressed and Substance-Abusing Parents
Children with substance abusing parents are at considerable risk for child maltreatment. The current study applied an actor–partner interdependence model to examine how father only (n=52) and dual couple (n=33) substance use disorder, as well as their depressive symptomology influenced parents’ own (actor effects) and the partner\u27s (partner effects) overreactivity in disciplinary interactions with their children, as well as their risk for child maltreatment. Parents completed the Center for Epidemiologic Studies Depression Scale (CES-D; Radloff, 1977), the overreactivity subscale from the Parenting Scale (Arnold, O’Leary, Wolff, & Acker, 1993), and the Brief Child Abuse Potential Inventory (Ondersma, Chaffin, Mullins, & LeBreton, 2005). Results of multigroup structural equation models revealed that a parent\u27s own report of depressive symptoms predicted their risk for child maltreatment in both father SUD and dual SUD couples. Similarly, a parent\u27s report of their own depressive symptoms predicted their overreactivity in disciplinary encounters both in father SUD and dual SUD couples. In all models, partners’ depressive symptoms did not predict their partner\u27s risk for child maltreatment or overreactivity. Findings underscore the importance of a parent\u27s own level of depressive symptoms in their risk for child maltreatment and for engaging in overreactivity during disciplinary episodes
Influence of Lorentz violation on Dirac quasinormal modes in the Schwarzschild black hole spacetime
Using the third-order WKB approximation and monodromy methods, we investigate
the influence of Lorentz violating coefficient (associated with a special
axial-vector field) on Dirac quasinormal modes in the Schwarzschild
black hole spacetime. At fundamental overtone, the real part decreases linearly
as the parameter increases. But the variation of the imaginary part with
becomes more complex. For the larger multiple moment , the magnitude of
imaginary part increases with the increase of , which means that presence of
Lorentz violation makes Dirac field damps more rapidly. At high overtones, it
is found that the real part of high-damped quasinormal frequency does not tend
to zero, which is quite a different from the symptotic Dirac quasinormal modes
without Lorentz violation.Comment: 10 pages, 4 figur
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