612 research outputs found

    Shape Coexistence in Pb186: Beyond-mean-field description by configuration mixing of symmetry restored wave functions

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    We study shape coexistence in Pb186 using configuration mixing of angular-momentum and particle-number projected self-consistent mean-field states. The same Skyrme interaction SLy6 is used everywhere in connection with a density-dependent zero-range pairing force. The model predicts coexisting spherical, prolate and oblate 0+ states at low energy.Comment: 5 pages REVTEX4, 4 eps figures, accepted by Phys. Lett. B. Revised version with some polishing of the text without changing its conten

    First Ever Observations of Mineral Dust in Wintertime over Warsaw, Poland

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    The long-range transport of desert dust over the area of the temperate climate zone is associated with the influx of hot air masses due to the location of the sources of this aerosol in the tropical climate zone. Between 24–26 February 2021, such an aerosol outbreak took place and reached Central Europe. The mean temperature of +11.7 °C was recorded during the event. A comparison of this value to the 20-year (2000–2020) average February temperature for Warsaw (−0.2 °C) indicates the uniqueness of the meteorological conditions. It was the first wintertime inflow of Saharan dust over Warsaw, the presence of which was confirmed by lidar and sun-photometer measurements. The properties of the desert dust layers were obtained; the mean values of the particle depolarization for the fully developed mineral dust layer were 13 ± 3% and 22 ± 4% for 355 and 532 nm, respectively. The aerosol optical thickness was high with average values >0.36 for all wavelengths smaller than 500 nm. The three-modal, aerosol size distribution was dominated by coarse-mode particles, with a visible contribution of accumulation-mode particles. It suggests the possible presence of other aerosol types

    Bone marrow and chelatable iron in patients with protein energy malnutrition

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    Objectives: To examine the iron status of malnourished children by comparing bone marrow iron deposits in children with protein energy malnutrition with those in well-nourished controls, and measuring chelatable urinary iron excretion in children with kwashiorkor. Design: Bone marrow iron was assessed histologicaHy in postmortem specimens from children with kwashiorkor or marasmus, and from controls. Twenty-four-hour urinary iron was measured in children with severe kwashiorkor, half of whom received 10 mg/kg of intramuscular desferrioxamine (DFO) on admission.  Setting: Red Cross War Memorial Children's Hospital, Cape Town. Subjects: Thirteen children with kwashiorkor, 6 with marasmus and 16 well-nourished children underwent bone marrow examination. Urinary iron excretion was assayed in 17 children with kwashiorkor. Results: Stainable iron was present in the bone marrow of half the children with kwashiorkor but in only 1 child in each of the other groups. The median iron excretion was 945.5 ”g/24 hours in the DFO group compared with 28.5 ”g/24 hours in the non-DFO group. Conclusions: There is an apparent excess of iron which may predispose to bacterial infections and free radicalmediated injury in children with kwashiorkor. S AFr Med J 1996; 86: 1410-141

    DNA methylation dynamics during early plant life.

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    Ligand-induced monoubiquitination of BIK1 regulates plant immunity

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    The detection of microorganism-associated ligands by plant cells activates a signalling cascade in which the kinase BIK1 is monoubiquinated, released from the FLS2-BAK1 complex, and internalized by endocytosis. Recognition of microbe-associated molecular patterns (MAMPs) by pattern recognition receptors (PRRs) triggers the first line of inducible defence against invading pathogens(1-3). Receptor-like cytoplasmic kinases (RLCKs) are convergent regulators that associate with multiple PRRs in plants(4). The mechanisms that underlie the activation of RLCKs are unclear. Here we show that when MAMPs are detected, the RLCK BOTRYTIS-INDUCED KINASE 1 (BIK1) is monoubiquitinated following phosphorylation, then released from the flagellin receptor FLAGELLIN SENSING 2 (FLS2)-BRASSINOSTEROID INSENSITIVE 1-ASSOCIATED KINASE 1 (BAK1) complex, and internalized dynamically into endocytic compartments. The Arabidopsis E3 ubiquitin ligases RING-H2 FINGER A3A (RHA3A) and RHA3B mediate the monoubiquitination of BIK1, which is essential for the subsequent release of BIK1 from the FLS2-BAK1 complex and activation of immune signalling. Ligand-induced monoubiquitination and endosomal puncta of BIK1 exhibit spatial and temporal dynamics that are distinct from those of the PRR FLS2. Our study reveals the intertwined regulation of PRR-RLCK complex activation by protein phosphorylation and ubiquitination, and shows that ligand-induced monoubiquitination contributes to the release of BIK1 family RLCKs from the PRR complex and activation of PRR signalling
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