MRI changes in psoriatic dactylitisextent of pathology, relationship to tenderness and correlation with clinical indices

Objectives. To quantify the extent of inflammation in psoriatic dactylitis and to examine the relationship between clinical and magnetic resonance imaging (MRI) data in both tender and non-tender dactylitis. Methods. Seventeen patients with psoriatic dactylitis underwent clinical assessment for 6 months after change of treatment, usually to methotrexate. Measures of dactylitis included the Leeds Dactylitis Index, the assessment tool used in the Infliximab in Psoriatic Arthritis Clinical Trial (IMPACT), a simple count of tender dactlylitic digits and a count of all dactylitic digits, both tender and non-tender. MRI scans of the affected hand or foot were performed before and after treatment using a 1.5T Siemens scanner pre- and post-contrast. Results. All patients improved clinically, as did their respective dactylitis scores and MRI images. The findings on MRI in both dactylitic and non-dactylitic digits were profound and widespread. The difference between tender and non-tender dactylitis was quantitative rather than qualitative. Synovitis and soft-tissue oedema were the most frequent abnormalities being present in 69 of tender dactylitic digits but bone oedema and flexor tenosynovitis were also frequently seen. Soft-tissue oedema was circumferential and enhancing and not limited to association with the flexor or extensor tendons. None of the clinical indices of dactylitis showed a close relationship to the extent of MRI abnormalities. Conclusions. MRI images demonstrate widespread abnormalities in digits of people with psoriatic arthritis. Tender dactylitic digits have more abnormalities than other digits but the relationship between clinical and MRI scores is not strong

Erodibility of hill peat

peer-reviewedThe project was funded by the European Union Structural Funds EAGGF distributed under the Department of Agriculture and Food Stimulus Fund.The energy necessary to entrain soil in water depends on the soil strength. Once entrained, the settling velocity of the eroded soil in water is of fundamental importance to the processes of sediment transport and deposition. In this paper, stream power theory and transport concepts coupled with the equation of continuity were used to derive a transport-limited peat concentration. The ratio of the log of the actual sediment concentration in surface run-off to the log of the transport-limited sediment concentration was the index of erosion used. The value of this index is a measure of the sensitivity of peat to erosion by sheet flow. Four peats were subjected to a range of overland flow rates under two slopes in a laboratory flume. The peats represented peat farmed in a sustainable manner (Leenane), overgrazed peat (Maam), peat undergoing erosion (Newport) and peat which had undergone weathering following exposure by a landslip (Croagh Patrick). Both in situ and surface damaged slabs were studied. The results indicate that shearing and remoulding of a wet peat surface (e.g., by animal treading) and weathering of exposed drained peat surfaces predispose peat to erosion. Defoliation by overgrazing is considered to be of secondary importance.Department of Agriculture, Food and the MarineEuropean Union Structural Funds EAGG

Adolescents' and parents' views of Child and Adolescent Mental Health Services (CAMHS) in Ireland

Aim: To explore adolescents’ and parents’ experiences of CAMHS in relation to accessibility, approachability, and appropriateness. Methods: Using a descriptive qualitative design, a combination of focus group and single interviews were conducted with adolescents (n=15) and parents (n=32) from three mental health clinics. Data were transcribed verbatim and analysed using thematic analysis. Results: Accessing mental health services was a challenging experience due to knowledge deficit, lack of information and limited availability of specialist services. Participants desired more information, involvement in decision-making, single and shared consultations, flexible scheduling of appointments, continuity with clinicians, school support and parent support groups. Participants seem to be generally satisfied, however adolescents felt less involved in decision making than they would have liked. Frequent staff changes was problematic as it disrupted continuity of care and hindered the formation of a trusting relationship. Implications for practice: Parents and adolescents expressed similar views of the positive and negative aspects of mental health services. Their need for more information-sharing and involvement in decision-making underline the importance of collaborative practice. Clinician continuity contributed to trusting therapeutic relationships and was valued. These are key principles that with attention, could lead to quality service provision for adolescents and families

Aspects of management options for pasture-based dairy production stocked at two cows per hectare

End of project reportWhite clover in association with Rhizobium bacteria have the capacity to fix or convent atmospheric N into plant available N. This can make a considerable contribution to sward productivity. One of the objectives of this experiment was to determine the upper carrying capacity of grass-white clover swards receiving 90 kg fertilizer N/ha. A second objective was to examine the impact of grass-clover swards on mineral-N in the soil and losses of nitrate-N from soil to drainage water during the winter. This experiment was conducted at Solohead Research Farm. There were three treatments: (i) A grass-only treatment (FN) stocked at 2.0 cows per ha in 2003 and 2.2 cows per ha during 2004, 2005 and 2006. This treatment received an average of 226 kg per ha of fertilizer N per year during these years. (ii) A grass-clover treatment (WC) stocked at the same rates as FN and received an average of 90 kg per ha of fertilizer N per year during the experiment. (iii) A grass-only treatment (CC) that was gradually converted over to grass-clover during the experiment and stocked at 2.0 cows per ha throughout the experiment. Fertilizer N input was gradually lowered from 150 kg per ha in 2003 to a target of 90 kg per ha in 2005 and 2006

The construction of an instrument for the evaluation of student teachers.

Thesis (Ed.M.)--Boston Universit

The Main Problem in Satellite Theory Revisited

Abstract. Using the elimination of the parallax followed by the Delaunay normalization, we present a procedure for calculating a normal form of the main problem (J2 perturbation only) in satellite theory. This procedure is outlined in such a way that an object-oriented automatic symbolic manipulator based on a hierarchy of algebras can perform this computation. The Hamiltonian after the Delaunay normalization is presented to order six explicitly in closed form, that is, in which there is no expansion in the eccentricity. The corresponding generating function and transformation of coordinates, too lengthy to present here to the same order; the generator is given through order four

Orbit propagation with Lie transfer maps in the perturbed Kepler problem

The Lie transfer map method may be applied to orbit propagation problems in celestial mechanics. This method, described in another paper, is a perturbation method applicable to Hamiltonian systems. In this paper, it is used to calculate orbits for zonal perturbations to the Kepler (two-body) problem, in both expansion in the eccentricity and closed form. In contrast with a normal form method like that of Deprit, the Lie transformations here are used to effect a propagation of phase space in time, and not to transform one Hamiltonian into another