Space station impact experiments

Four processes serve to illustrate potential areas of study and their implications for general problems in planetary science. First, accretional processes reflect the success of collisional aggregation over collisional destruction during the early history of the solar system. Second, both catastrophic and less severe effects of impacts on planetary bodies survivng from the time of the early solar system may be expressed by asteroid/planetary spin rates, spin orientations, asteroid size distributions, and perhaps the origin of the Moon. Third, the surfaces of planetary bodies directly record the effects of impacts in the form of craters; these records have wide-ranging implications. Fourth, regoliths evolution of asteroidal surfaces is a consequence of cumulative impacts, but the absence of a significant gravity term may profoundly affect the retention of shocked fractions and agglutinate build-up, thereby biasing the correct interpretations of spectral reflectance data. An impact facility on the Space Station would provide the controlled conditions necessary to explore such processes either through direct simulation of conditions or indirect simulation of certain parameters

“You can help people”: Adolescents’ Views on Engaging Young People in Longitudinal Research

We sought to discover adolescents’ thoughts about participation in longitudinal research and identify recruitment and retention strategies that were meaningful to them. We conducted seven focus groups with 10–15-year-olds in two large rural centers in New South Wales, Australia, and all focus groups were digitally recorded, transcribed, and analyzed. Adolescents discussed factors salient to their involvement in focus groups, as well as factors that may influence involvement in a longitudinal study. At the outset of the focus groups, adolescents had a positive view of “research,” but were reluctant to engage in research that involved biologic samples. Effective recruitment of adolescents requires an appreciation of motivators, and time and resources to extend potential participants’ understanding.Supported by Sydney Medical School Foundation

Text messaging is a useful reminder tool

Introduction Longitudinal studies of adolescents must be ‘adolescent-friendly’, to collect data and to encourage maintenance in the study cohort. Text messaging may offer a feasible means to do both. Methods Adolescents in the Adolescent Rural Cohort, Hormones and Health, Education, Environments and Relationships (ARCHER) study (n=342) are sent automated text messages every 3 months, prompting biological specimen collection. Results A total of 99.2% of participants (or their parents) owned a mobile phone, of which 89.1% of participants responded to text messages and 97.3% of intended urine samples were collected. The average time to provide a urine sample after prompting correlated with time to reply to Short Message Service (SMS). Conclusions This study shows SMS can be used effectively in longitudinal research involving adolescents and is feasible and useful as a reminder tool for regular biological specimen collection.Australian National Health and Medical Research Counci

Remote sensing and geologic studies of the orientale basin region

Both visual and near-infrared spectral observations are combined with multispectral imaging to study the Orientale interior and exterior, the Cruger region, Grimaldi Region, the Schiller-Schickard Region, and the Humorum Region of the Moon. It was concluded that anorthosites occur in the Inner Rook Mountains of Orientale, the inner ring of Grimaldi, and the main ring of Humorum. Imaging spectroscopy shows that the entire eastern Inner Rook Mountains are composed of anorthosites. Orientale ejecta are strikingly like the surface materials in the region where Apollo 16 landed. This similarity indicates similar mineralogy, i.e., noritic anorthosite. Thus, Orientile ejecta is more mafic than the Inner Rook Mountains. This situation is also true for the Nectaris, Humorum, and Gramaldi basins. Isolated areas of the Orientale region show the presence of gabbroic rocks, but, in general, Orientale ejecta are noritic anorthosites, which contain much more low-Ca pyroxene than high-Ca pyroxene. Ancient (pre-Orientale) mare volcanism apparently occurred in several areas of the western limb

Spatial characteristics of species distributions as drivers in conservation prioritization

Peer reviewe

Intersectionality: Social Marginalisation and Self-Reported Health Status in Young People.

BACKGROUND:The aim of this study was to measure young people's health status and explore associations between health status and belonging to one or more socio-culturally marginalised group. METHODS:part of the Access 3 project, this cross-sectional survey of young people aged 12-24 years living in New South Wales, Australia, oversampled young people from one or more of the following groups: Aboriginal and or Torres Strait Islander; living in rural and remote areas; homeless; refugee; and/or, sexuality and/or gender diverse. This paper reports on findings pertaining to health status, presence of chronic health conditions, psychological distress, and wellbeing measures. RESULTS:1416 participants completed the survey; 897 (63.3%) belonged to at least one marginalised group; 574 (40.5%) to one, 281 (19.8%) to two and 42 (3.0%) to three or four groups. Belonging to more marginalised groups was significantly associated with having more chronic health conditions (p = 0.001), a greater likelihood of high psychological distress (p = 0.001) and of illness or injury related absence from school or work (p < 0.05). CONCLUSIONS:increasing marginalisation is associated with decreasing health status. Using an intersectional lens can to be a useful way to understand disadvantage for young people belonging to multiple marginalised groups

Access 3 project protocol: Young people and health system navigation in the digital age: A multifaceted, mixed methods study

© 2017 Article author(s). Background: The integration of digital technology into everyday lives of young people has become widespread. It is not known whether and how technology influences barriers and facilitators to healthcare, and whether and how young people navigate between face-to-face and virtual healthcare. To provide new knowledge essential to policy and practice, we designed a study that would explore health system access and navigation in the digital age. The study objectives are to: (1) describe experiences of young people accessing and navigating the health system in New South Wales (NSW), Australia; (2) identify barriers and facilitators to healthcare for young people and how these vary between groups; (3) describe health system inefficiencies, particularly for young people who are marginalised; (4) provide policy-relevant knowledge translation of the research data. Methods and analysis: This mixed methods study has four parts, including: (1) a cross-sectional survey of young people (12-24 years) residing in NSW, Australia; (2) a longitudinal, qualitative study of a subsample of marginalised young people (defined as young people who: identify as Aboriginal and/or Torres Strait Islander; are experiencing homelessness; identify as sexuality and/or gender diverse; are of refugee or vulnerable migrant background; and/or live in rural or remote NSW); (3) interviews with professionals; (4) a knowledge translation forum. Ethics and dissemination: Ethics approvals were sought and granted. Data collection commenced in March 2016 and will continue until June 2017. This study will gather practice and policy-relevant intelligence about contemporary experiences of young people and health services, with a unique focus on five different groups of marginalised young people, documenting their experiences over time. Access 3 will explore navigation around all levels of the health system, determine whether digital technology is integrated into this, and if so how, and will translate findings into policy-relevant recommendations

Journeying from “I” to “we”: assembling hybrid caring collectives of geography doctoral scholars

This is an Accepted Manuscript of an article published by Taylor & Francis in "Journal of Geography in Higher Education" on 15 June 2017, available at: https://www.tandfonline.com/doi/full/10.1080/03098265.2017.133529

Limited sampling estimates of epigallocatechin gallate exposures in cirrhotic and noncirrhotic patients with hepatitis C after single oral doses of green tea extract.

BACKGROUND: Epigallocatechin-3-gallate (EGCG) has antiangiogenic, antioxidant, and antifibrotic properties that may have therapeutic potential for the treatment of cirrhosis induced by hepatitis C virus (HCV). However, cirrhosis might affect EGCG disposition and augment its reported dose-dependent hepatotoxic potential. OBJECTIVE: The safety, tolerability, and disposition of a single oral dose of EGCG in cirrhotic patients with HCV were examined in an exploratory fashion. METHODS: Eleven patients with hepatitis C and detectable viremia were enrolled. Four had Child-Pugh (CP) class A cirrhosis, 4 had Child-Pugh class B cirrhosis, and 3 were noncirrhotic. After a single oral dose of green tea extract 400 mg containing 94% pure EGCG, blood for EGCG levels and safety parameters was ascertained at 2, 4, and 10 hours. RESULTS: C(max) and AUC to EGCG overlapped among the 3 groups, which suggests that the disposition of EGCG was not significantly altered in these patients with cirrhosis. CONCLUSIONS: A single 400-mg oral dose of EGCG was safe and well tolerated by all of the patients in the study. These results provide guidance for the continued investigation of the long-term safety and antitumor potential of EGCG in cirrhotic patients with HCV